Rik Lindeboom

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation Profiling antigens presented on MHC class I molecules on the cell surface is essential to identify candidate antigens for targeted and personalized immunotherapies. However, mass spectrometry-based im...

Preprint alert! 🚨 Presenting MHC1-TIP: a scalable, cost-effective workflow for MHC-I ligandome + proteome profiling from diverse samples, to for example uncover intratumoral heterogeneity in RCC. Spearheaded by Mayukha Bathini, and big thanks to all collaborators! biorxiv.org/content/10.1...

Are you a group leader within the research field Chemistry of Life? Would you like to strengthen your network? Then join us at the Chemistry of Life community day 2025 on 17 April @tudelfttnw.bsky.social

Register 👇
www.nwo.nl/en/meetings/...
deadline: 10 April

Grateful to have received the ZonMW Open Competition grant together with @chirlmin.bsky.social. We will combine molecular engineering, single-molecule imaging, and genomics to investigate the binding kinetics of antigens to MHC class II and T cell receptors. Exciting times ahead!

Excited to share that our single-cell proteomics workflows at @nkinl.bsky.social just got a major upgrade with the installation of the cellenONE single-cell isolation robot! This tech will help us push the boundaries of proteomics in cancer, one cell at a time.

We're proud to participate with top labs in this prestigious PhD program. There's less than a month left to apply, don't miss this opportunity!

39 miljoen voor nieuw onderzoek en medicijnontwikkeling KWF investeert 39 miljoen euro in nieuw kankeronderzoek, waarvan 11 miljoen bestemd is voor academische geneesmiddelontwikkeling.

I'm incredibly grateful to have received the Young Investigator Grant from KWF and Alpe d'HuZes! This grant will support our work on understanding how antigen presentation dynamics are regulated and how these processes occur in penile cancers.

The #Proteomics Facility at The Netherlands Cancer Institute is seeking to expand its team with a #technician! This is an exciting opportunity to contribute to cutting-edge clinical and cell biology projects using state-of-the-art proteomics technologies. Share or apply via the link below.

Exciting news for aspiring #PhD students: the NKI PhD Program 2025 will open soon for applications! We participate with multiple top labs in this prestigious program, which offers a unique opportunity for PhD candidates to engage in cutting-edge genome biology and cancer research. #Science