Audrey Luo

Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis Depression is a common and debilitating psychiatric disorder that is associated with substantial morbidity and mortality. For nearly 40 years, scientists have attempted to localize depression in the b...

Excited to share that our new review, "Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis," is out now in Biological Psychiatry! We propose MS as a powerful model for studying how white matter network changes contribute to depression.

🧠I am excited to announce that our manuscript introducing a new data resource – PennLEAD (Penn Longitudinal Executive functioning in Adolescent Development) – is now available on bioRxiv. Below are some details highlighting our data resource🧵funded by NIMH R01MH113550
www.biorxiv.org/content/10.1...

Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵

Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications The landmark ongoing HEALthy Brain and Cognitive Development (HBCD) study will longitudinally chart brain development in a large sample (projected n=7,200) of infants through age 10 years with multimo...

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...

🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵

nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging

Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉

📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io

New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇

www.biorxiv.org/cgi/content/...

SYPRES (Synthesis of Psychedelic Research Studies) logo

🍄 Our new living systematic review and meta-analysis on psilocybin for depression is out. Here's what we found and the open science infrastructure we built to support it 🧪🧵
www.medrxiv.org/content/10.1...

Congrats @audreycluo.bsky.social!! Celebrating a wonderful dissertation defense that shed novel, fundamental, and convincing insights into white matter development.

Thank you reproducibilibuddy / dMRI extraordinaire!!

@audreycluo.bsky.social has had one of the most impressive graduate careers I've ever seen. Kudos!!!!

🥺thanks Parker!!

So grateful to @ted-satterthwaite.bsky.social for being the most wonderful PhD adviser and @pennlinc.bsky.social for being my lab home. My heart is full 🩷🧡💛

Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

#NGG is proud to present our next Thesis Defense given by Audrey Luo @audreycluo.bsky.social of the Satterthwaite Lab
@ted-satterthwaite.bsky.social ! Please join us in person or virtually (DM us for the link) on 8/5. Best of luck, Audrey! #PhAlmostDone 🥳

Such beautiful and careful work from @valeriejsydnor.bsky.social, as always!!

The ABCD Study 6.0 release is finally here! 🧠 Apply for data access here @theabcdstudy.bsky.social www.nbdc-datahub.org

Alert! ... for the child development world!

@fluxsociety.bsky.social @fitngin.bsky.social ‪

The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive.

Check here:
docs.hbcdstudy.org

and here:
nbdc-datahub.org

Here’s why it matters 🧠🍼

@kevin-y-sun.bsky.social‬ will be presenting his work on "Copy Number Variant Risk Scores Are Associated with Personalized Functional Brain Network Topography" Wed, June 25, 13:15 - 15:15 & Thus, June 26, 13:45 - 15:45

a cartoon of snoopy dancing with the words oh yeah written above him ALT: a cartoon of snoopy dancing with the words oh yeah written above him

#OHBM2025 is here and the champs from @pennlinc.bsky.social have brought their freshest work express from Philly to Brisbane. Thread below . . .please reach out + come say hi -- always looking to talk science + make new friends!!!

@audreycluo.bsky.social will be presenting her fab work on "Two Axes of White Matter Development" on Wed, June 25, 13:15 -15:15 & Thurs, June 26, 13:45 -15:45; Poster #1010.

Thanks @gradientsworkshop.bsky.social for a fantastic day of science and for inviting me to speak!! 🌈🧠

So excited to share that my first paper is out in BMJ Open! Thank you @ballerlab.bsky.social and the amazing team of people that made this possible! 🧠🌟

The Baller Lab is thrilled to announce that @elenaccooper.bsky.social just had her first first-author publication! “Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol” is now published on BMJ Open: bmjopen.bmj.com/content/15/5/e094733! 🧠

Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature Communications The underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon...

Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below!

doi.org/10.1038/s414...

Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...

Welcome to Save The U.S. National Science Foundation A Girl Looking at a Physics Model TAKE ACTION Save NSF is a coalition of concerned scientists and allies who are working to save funding for scientific grants through the U.S. National Science Foundation. Our mission is to support and advocate for the continuation of vital research and innovation in various scientific fields. NSF funding is critical to this work. Join us in our endeavor to ensure a sustainable future for scientific exploration and discovery.

I am so heartened to this seriously AWESOME #SaveNSF website go up today!!!!

Has a take action toolkit with:

1. Press outreach templates
2. Social media toolkit
3. Elected official outreach
4. Talking points

Check it out and share widely!!!! Likely more to come.

www.savensf.com

Excited to share that our paper is now in press at the British Journal of Psychiatry! Looking forward to presenting our work this Friday at #SOBP2025 in our symposium: "Does one size fit all? Subgroup Modeling of Brain-Behavior Relationships in Psychiatry" 🧠

#neuroskyence #neuroimaging #psychscisky

Multimodal precision MRI of the individual human brain at ultra-high fields - Scientific Data Scientific Data - Multimodal precision MRI of the individual human brain at ultra-high fields

Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲

www.nature.com/articles/s41...

osf.io/mhq3f/

@borismontreal.bsky.social @jroyer.bsky.social @themindwanders.bsky.social @jordandekraker.bsky.social

Study human brain structure and function with our new open access 7T MRI dataset

led by superstar scientist @donnagift.bsky.social ↙️