APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses
Excess lipid droplet (LD) accumulation is implicated in various diseases, including Alzheimer's disease (AD), yet the mechanisms underlying this accumโฆ
What does the APOE 'lipid droplet-ome' look like???
Check out our new paper to find out!
www.sciencedirect.com/science/arti...
Thanks to first authors @cassifriday.bsky.social and @iostephens.bsky.social
+help from Scott Gordon @morganti.bsky.social and @cohenlaboratory.bsky.social labs
03.06.2025 01:09 โ ๐ 22 ๐ 13 ๐ฌ 1 ๐ 0
Text reads "Congratulations to the 2025 Leading Edge Fellows" followed by the Leading Edge logo and www.leadingedgesymposium.org. Below are the headshots and names of the 40 new Leading Edge Fellows. They are
Cel Welch
Lianna Wat
Maria Toro Moreno
Sarah Talley
Xulu Sun
Ines Sturmlechner
Virginia Savy
Amelie Raz
Kali Pruss
Caterina Profaci
Sarah Pierce
Melissa Pamula
Kehinde Odufowora
Patricia Nano
Ariana Musa de Aquino
Nour El Houda Mimouni
Kathleen Martin
Brea Manuel
Mable Lam
Miri Krupkin
Elaine Kouame
Megan Kirchgessner
Sumin Kim
Shubhangini Kataruka
Geraldine Jowett
Andrea Jones
Leanne Iannucci
Emily Heckman
Allison Girasole
Florencia Fernandez Chiappe
Tonie Farris
Hannah Elam
Erin Doherty
Xiaoyun Ding
Maria Bustillo
Julia Brunner
Debadrita Bhattacharya
Lorena Benedetti
Ashley Anderson
Krisha Aghi
We are thrilled to announce the 2025 Leading Edge Fellows! 40 outstanding postdoctoral fellows doing pioneering research in a wide range of biological and biomedical disciplines.
Learn more about these exceptional scientists:
www.leadingedgesymposium.org/fellows
27.05.2025 16:56 โ ๐ 162 ๐ 63 ๐ฌ 6 ๐ 40
BioImageArchive < The European Bioinformatics Institute < EMBL-EBI
The BioImageArchive โ a free, publicly available online resource which stores and distributes biological images
Did you know that Bioimage Archive has a specific database for people to share AI-ready imaging datasets? I did not until @yanlanmao.bsky.social told me! Please deposit! If people regularly submitted, it would have a huge collective impact on bioimage analysis. www.ebi.ac.uk/bioimage-arc...
21.05.2025 14:53 โ ๐ 48 ๐ 25 ๐ฌ 3 ๐ 0
๐จ New WP! ๐ "Publish or Procreate: The Effect of Motherhood on Research Performance" (w/ @valentinatartari.bsky.social
๐ฉโ๐ฌ๐จโ๐ฌ We investigate how parenthood affects scientific productivity and impact โ and find that the impact is far from equal for mothers and fathers.
22.05.2025 08:03 โ ๐ 181 ๐ 91 ๐ฌ 2 ๐ 5
Congratulations to Cohen Lab alumnus @joshilaboratory.bsky.social on his first senior-author paper! Beautiful work! ๐
23.05.2025 21:08 โ ๐ 10 ๐ 0 ๐ฌ 0 ๐ 0
The abstract submission deadline for the 2nd edition of our #EMBOLipidDroplets Workshop (21-26 September 2025) is approaching.
Check out the agenda with an amazing lineup of speakers and submit your abstract before 10 June 2025!
@embo.org
@biologists.bsky.social
meetings.embo.org/event/25-lip...
14.05.2025 08:57 โ ๐ 9 ๐ 8 ๐ฌ 0 ๐ 0
Multiple recent studies, including 3 impressive natural experiments, consistently show a link between Shingles vaccines and reduced dementia. This week a nationwide S Korea study added a reduction of cardiovascular events
My summary Table. More here on dementia erictopol.substack.com/p/the-shingl...
11.05.2025 21:27 โ ๐ 942 ๐ 302 ๐ฌ 26 ๐ 37
Reminded me of my own PhD graduation in 2011. Here I am with my PhD advisor, Dr. Nelly Pante.
10.05.2025 16:23 โ ๐ 5 ๐ 0 ๐ฌ 0 ๐ 0
So fun to hood Dr. Shannon Rhoads at the UNC Doctoral Hooding Ceremony today! I got to bust out my U British Columbia regaliaโฆ
10.05.2025 16:22 โ ๐ 32 ๐ 1 ๐ฌ 1 ๐ 0
Super cool work from the Henne Lab identifies the antioxidant enzyme APMAP at the intersection of ER stress, lipid oxidation, and lipoprotein secretion. Congratulations Blessy, Mike, and team! ๐
05.05.2025 18:36 โ ๐ 7 ๐ 0 ๐ฌ 0 ๐ 0
Reminder: The 1st FASEB #Ferroptosis Meeting is this summer! Spectacular speaker lineup + short talks selected from submitted abstracts. It is going to be awesome! Trainees, newcomers & all interested are welcome!
๐
Abstract deadline: June 1, 2025.
shorturl.at/QA6T1
03.05.2025 17:09 โ ๐ 22 ๐ 8 ๐ฌ 0 ๐ 3
On April 19, 1898, Camillo Golgi described what we now know as the #Golgi apparatus - a structure so pretty and unusual it took over fifty years for the scientific community to agree it wasnโt just an artefact.
April 19 is #GolgiDay! Mark your calendars to honour the best organelle.
16.04.2025 19:39 โ ๐ 85 ๐ 28 ๐ฌ 4 ๐ 9
Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.
10.04.2025 13:38 โ ๐ 488 ๐ 166 ๐ฌ 7 ๐ 16
Molecular Biology of the Cell (MBoC)
If you're working on innovative cell biology research, Molecular Biology of the Cell (MBoC) is the place to share it.
Iโm proud to serve on the editorial team
Submit your work today: www.molbiolcell.org
#CellBiology #MBoC #ScientificPublishing
@ascbiology.bsky.social
08.04.2025 18:25 โ ๐ 30 ๐ 10 ๐ฌ 1 ๐ 0
Yes! Please come or send folks from your lab
27.03.2025 22:52 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0
I am beyond thrilled to co-organize this FASEB #LipidDroplet conference with Mike @hennelab.bsky.social in 2026! Check out the lineup and plan to participate - you do not want to miss this one!! #lipidtime
27.03.2025 18:11 โ ๐ 34 ๐ 10 ๐ฌ 1 ๐ 0
Mark your calendars & repost! Join us for the 2026 FASEB Lipid Droplets Conference!
July 26-30, 2026 in beautiful Scottsdale, Arizona.
Best of all: The FASEB Lipid Droplet meeting is co-locating with the FASEB Phospholipid meeting. Two wonderful lipid communities brought together!
27.03.2025 13:59 โ ๐ 11 ๐ 6 ๐ฌ 0 ๐ 1
These are the specific foods that were linked with healthy aging and other outcomes. Green-favorable; Red-unfavorable
24.03.2025 16:03 โ ๐ 74 ๐ 16 ๐ฌ 12 ๐ 11
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social
24.03.2025 16:03 โ ๐ 461 ๐ 112 ๐ฌ 20 ๐ 15
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications
Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...
๐ Very happy to see this out! A real group effort from the Hyslop lab (@thecimr.bsky.social) including brilliant collaborations with
@knowleslab.bsky.social,
Vendruscolo lab, @michael-e-ward.bsky.social lab,
@deriverylab.bsky.social lab,
@profmarciniak.bsky.social lab
๐๐๐
24.03.2025 15:02 โ ๐ 41 ๐ 11 ๐ฌ 1 ๐ 2
Nice interview with my inspiring postdoc advisor Jennifer Lippincott-Schwartz
21.03.2025 14:27 โ ๐ 11 ๐ 0 ๐ฌ 0 ๐ 0
Very excited to see this study out in the world. We made what is (we think?) the first fully-humanized mouse model of a repeat expansion disorder, DRPLA, by replacing an entire copy of muring Atn1 with human ATN1 with 112 pure CAG repeats...
www.biorxiv.org/content/10.1...
20.03.2025 14:00 โ ๐ 12 ๐ 4 ๐ฌ 1 ๐ 2
Lipid Research Division Seminar Series
March 26, 2025 | 12 p.m. Eastern
Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.
We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.
Register here! www.asbmb.org/meetings-eve...
14.03.2025 17:35 โ ๐ 17 ๐ 8 ๐ฌ 0 ๐ 1
Dear #LipidDroplet friends, we are so much looking forward to the 2nd edition of our #EMBOLipidDroplets Workshop. Join us 21-26 September 2025 at beautiful Costa Brava!
Abstract submission deadline is 10 June 2025.
@embo.org
@biologists.bsky.social
meetings.embo.org/event/25-lip...
11.03.2025 15:17 โ ๐ 17 ๐ 11 ๐ฌ 0 ๐ 0
A few spots left and deadline extended to March 14th! Many opportunities for talks with 16 talks plus 24 flash talks selected from abstracts! Please repost!
11.03.2025 11:18 โ ๐ 13 ๐ 10 ๐ฌ 0 ๐ 0
Details & Zoom link: felixcampelo.wixsite.com/membranetraf...
Join Felix @felixmendu.bsky.social, Francesca @franbottanelli.bsky.social, Sarah Cohen @cohenlaboratory.bsky.social, David Teis @teislab.bsky.social and me for some great discussions on organelle dynamics and quality control!
10.03.2025 07:23 โ ๐ 5 ๐ 3 ๐ฌ 0 ๐ 0
she/her
PhD student at Penn with an interest in neurodegeneration
Mom, mitochondriac and confocal microscopist. Microscopy Core Manager at the Medical College of Wisconsin.
Opinions = mine
https://orcid.org/0000-0003-2140-5739
https://mcw.ilab.agilent.com/service_center/show_external/5443/electron_microscopy_facility
Cell cycle, mitosis, nuclear pores, ubiquitin, disease.
Group leader @igbmc.bsky.social, research director DR1 @cnrs.fr, Strasbourg, France.
Alumna @JagiellonskiUni.bsky.social @impvienna.bsky.social @ethz.ch
Hobby cook and occasional runner.
I love dinoflagellates and polymer physics. PhD student @QLSMcGill.
https://github.com/lucasphilipp1
NOT SPAM. But I was reported and nothing I can do. So this account will be inactive: find me on LinkedIn, the only platform working well.
At least the bots can flourish here. Sigh.
Director General/
Natural Resources Canada
PhD student in Theoretical Biophysics at University of Dundee. Studying active matter physics with applications in the behaviour and mechanics of actomyosin networks.
Asst. Prof. in Physics
LSA Collegiate fellow
University of Michigan
Previously JF at Harvard & PhD at SU
he/him
https://sites.lsa.umich.edu/shankar-lab/
How function emerges collectively in soft, active, living matter? | Physics, maths, & biology
Developmental biologist ๐๐งฌ
Postdoc @mdc-berlin.bsky.social
Previously @espciparispsl.bsky.social | PhD @sorbonne-universite.fr
Associate Professor in Bioengineering ๐ฎ๐น@ Linkรถping University ๐ธ๐ช
Bioengineering/Genomics/Development/3R/Teeth/HeavyMetal/Photography
Postdoc in @liganlab.bluesky.social at Weill Cornell Medicine interested in resilience and microglia in neurodegeneration โข Vanderbilt Neuro PhD โ22 โข Kenyon College โ17 โข 1st gen Egyptian-American
Microscopic farmer ๐ฌ๐บ
Microscopy core director @UNC Chapel Hill
Former plant developmental biologist
Associate Professor in Physiology at UT Southwestern Medical Center. I study calcium signaling, lipid metabolism and organelle membrane contact sites.
GENEWIZ from Azenta Life Sciences is a leading global multiomics service provider serving researchers worldwide through a suite of solutions including synthesis, Sanger sequencing, whole plasmid sequencing, and next generation sequencing.
RNA & Metabolism. Ancient companions for Life. RNA as spatial organizer of the Cell. IDPs, biomolecular condensates and RNA fun @HymanLab. And birds.
ebird.org/profile/MjcyMDU0Nw
inaturalist.org/people/9261834
Developmental Neurobiologist looking for opportunities to start a lab!
Scott Williams Lab | Center for Gastrointestinal Biology and Disease
UNC Chapel Hill | Durhamite
#devbio #gut-brain
Follow my journey to advance research with Cure HHT, to advocate for science policy & military families, and through the wild ride of parenting 3 wildlings.
Professor & head, Educational Leadership & Policy Studies, University of Tennessee, Knoxville. I study higher ed finance, accountability, and financial aid. Washington Monthly rankings data editor. Dad, gardener, and baker.
https://robertkelchen.com/
Assistant professor at Copenhagen Business School and postdoc at University of Zรผrich. Focus on labor, gender, benefits & policy, and economics of science and science funding. Applied & behavioral econ. PhD from @Economics_UCPH.
The official account for the Life Science Solutions division of the Nikon Healthcare Business, with a focus on biological microscopy products and services for the life science, biotech/pharma, and clinical laboratory markets.