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Brian Shim

@brianhshim.bsky.social

PhD candidate in David Liu’s lab at Harvard and Broad Institute. Applying gene editing, targeted delivery, and protein evolution to develop new immunotherapies.

147 Followers  |  287 Following  |  1 Posts  |  Joined: 16.11.2024  |  1.3521

Latest posts by brianhshim.bsky.social on Bluesky

Excellent!

15.05.2025 19:13 — 👍 1    🔁 0    💬 0    📌 0
Preview
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...

Excited to introduce evoCAST: a platform for efficient, programmable gene integration in human cells. This work, a close collab between my PhD lab (Liu group) and @sternberglab.bsky.social, has been such a fun journey to help lead. Huge thanks to all contributors!

www.science.org/doi/10.1126/...

15.05.2025 19:06 — 👍 18    🔁 4    💬 1    📌 2
Post showing precipitous decline of share of deaths in Massachusetts from diseases for which vaccines are now available, from 70% in 1840 to low digits % by 1950-60 where it is stayed. 

Caption: There are not many places on earth where we have detailed cause-of-death data from before the era of widespread vaccination.

Massachusetts is one of those places.

From 1842-1877, 70% of all deaths were from diseases which we today have vaccines to prevent.

Post showing precipitous decline of share of deaths in Massachusetts from diseases for which vaccines are now available, from 70% in 1840 to low digits % by 1950-60 where it is stayed. Caption: There are not many places on earth where we have detailed cause-of-death data from before the era of widespread vaccination. Massachusetts is one of those places. From 1842-1877, 70% of all deaths were from diseases which we today have vaccines to prevent.

Anyone who is anti-vax is pro-death. Period. The science and data do not lie. And they don’t care about your podcast.

24.11.2024 22:52 — 👍 26580    🔁 5760    💬 560    📌 199

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