Denise Fitzgerald

Myelin sheaths in the central nervous system can withstand damage and dynamically remodel Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...

I am delighted to see this work published. A big thanks to everyone, particularly the excellent supervision of @lyons-lab.bsky.social, the work of co-first author @juliavdkorput.bsky.social and wonderful collaborators in Amsterdam and Oregon.
www.science.org/doi/10.1126/...

Excellent advice

Recommendations for where to advertise Postdoc jobs for wide reach these days? Free and fee-based suggestions welcomed. Jobs based Ireland in neuroimmunology.Thanks!

Antigen specificity of clonally enriched CD8+ T cells in multiple sclerosis - Nature Immunology Sabatino and colleagues examine expanded CD8+ T cell clonotypes from a small cohort of multiple sclerosis patients. They identified several cognate peptide epitopes that derive from Epstein–Barr virus...

Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8+ T cells in #multiplesclerosis #EBV in @natimmunol.nature.com #immunology 🧪🧵1/

www.nature.com/articles/s41...

Large study finds COVID-19 shots don’t affect fertility

Among almost 60,000 women aged 18 - 45 in one Swedish county, #Covid #Vaccination did not affect the chance of getting or staying #pregnant.

I know of at least a dozen studies that have shown this, but this is by far the biggest! I spoke to @lizszabo.bsky.social

Love Your Health: | NI Science Festival

🧪 Want to discover what science really does for your health? Join the Love Your Health event on Sat 14 Feb, 1–4:30pm! Meet local scientists, try hands-on activities & explore research that matters to ALL ages. 💡👨‍👩‍👧‍👦 #NIScienceFest nisciencefestival.com/event/love-y...

We want to develop a Centre of Excellence for MS Research in Northern Ireland, and we want to hear your opinions!

Please share!

Next Meeting: 29th January 2026
You will be reimbursed for travel expenses.

For more information, contact: info@msresearchni.co.uk

#multiplesclerosis
#MSResearchNI

🎂 What a nice b-day surprise: 🏆 Congrats to Chengyu Zou on this timely and outstanding Cell Perspective on regulatory T cells.
🧬 Perfectly aligned with the Nobel spotlight on Tregs.

Source:
Zou C. et al., Cell (2026).

authors.elsevier.com/c/1mPZDL7PXu...

🔬 PhD Opportunity in Cancer Cell Biology 🔬
Are you an enthusiastic and ambitious scientist looking for a PhD project in cancer cell biology? Apply to join as a PhD student in Emma Evergren's group to help tackle fundamental questions in cancer cell biology.

Apply by 30 January
lnkd.in/eDrBp-J9

‘Giant step forward’ for Huntington’s — the scientist behind the first gene therapy Sarah Tabrizi is part of Nature’s 10, a list of people who shaped science in 2025.

We're delighted that Professor Sarah Tabrizi (@uclqsion.bsky.social) is part of Nature’s 10, a list of people who shaped science in 2025.
Her team's global trial at @ucl-hd.bsky.social showed a new Huntington’s treatment could slow progression by 75%.

In the year that Tregs get the respect they deserve - here is our contribution to help understand what regulates their homeostasis. One for lovers of cytokines and Tregs! www.pnas.org/doi/10.1073/...

Congratulations!!

YouTube video by ALL Institute Could the eye be a window to the brain in MS? Dr. Michelle Naughton, Queens University Belfast

At AIMSRN2025, our team highlighted why the eye matters in MS research. Catch up on the talks via the YouTube links below - worth a watch!

Dr Gavin McDonnell
www.youtube.com/watch?v=kUtm...

Dr. Michelle Naughton
www.youtube.com/watch?v=P-f4...

Dr Lajos Csincsik
www.youtube.com/watch?v=EE5D...

Earlier this month, we trained on the new M2OCT at the NI Clinical Research Facility-thanks to Imagine Eyes! This hi-res tech will boost eye research in MS, glaucoma, Alzheimer’s & more, led by Queen’s University Belfast. Thanks to our funders incl. Jules Thorn Trust & iREACH Health! #MSResearchNI

Last week, Prof. Imre Lengyel and Dr. Lajos Csincsik joined the Eyes on the Brain meeting hosted by Optos in Edinburgh to explore how eye imaging and AI could help detect and monitor brain and nerve conditions, including MS. Thanks to Optos for the invitation and inspiring discussions!

#MS #retina

🔬 Last month, our NI MS Research Hub team shared how the retina may help us better understand Multiple Sclerosis (MS).

We presented at the World Sight Day & Pan-Ireland Ophthalmic Meeting in Belfast — a great chance to link eye and brain health to support people with MS. 👁️🧠

#MSResearchNI #WSD2025

🎉 Huge congrats to Nira for winning Best Postdoctoral Research Talk at the Irish Society of Immunology Conference in Galway! 👏

She presented exciting work on how the brain repairs itself in MS, highlighting immune receptors that support remyelination.

#MSResearchNI @qubelfastofficial.bsky.social

Can you add me to this starter pack please?

Join the Glia community on bluesky go.bsky.app/Lyzro3M

Hugely deserved, congratulations 🎉🎉

I hope this Nobel Prize gets people talking meaningfully about our amazing immune systems and the importance of basic research to human health (and funding basic research).

I am also glad young women get to see that women can not only work at this level, but that those who do can get recognized.

Oh how sad

Really a towering figure, whose work laid the ground for stem cells, regenerative biology etc

I go to know him well over many years and he was definitely one-of a-kind...

Great summary on the back story to this year's Nobel Prize

Huge congratulations Prof Dooley - delighted to hear of this so well deserved recognition!

Phenomenal achievement

Then moving from high to low budget (common at new PI stage) coupled with lots of unforeseen costs if setting up a new lab and the 'what if I mess this up' concern can make spending decisions challenging

I've experienced both and moving from low budget to high took some adjustment. More money to spend but greater expectations and shorter time frames for delivery.

Fantastic thread on budgeting from @labliston.bsky.social . Great advice for new (and not so new!) PIs. I would add awareness of how psychology impacts spending based on moving from low budget to high budget setting and vice versa....

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Love this!