Arrived in beautiful, picturesque #Bressanone for #PhysicsOfBiomolecules! Excited for the talks and discussions and to present @vicidominilab.bsky.social's work on #SPAD array detectors for #FCS. We also have open positions @iitalk.bsky.social in Genoa! Feel free to reach out! @erc.europa.eu
Andrea Bucci and Laurent Le will run two workshops on building a custom #PhotonResolvedMicroscopy system and generating great #ImageScanningMicroscopy images.
Thanks @iitalk.bsky.social @erc.europa.eu @genoainstruments.bsky.social and #PNRR RNA&GeneTheraphy for support. See you at #Mifobio2025
Great, Luciano! Thanks a lot for sharing your thoughts!
Happy to share this article with my views on @elislenders.bsky.social and @vicidominilab.bsky.social work and discussing current developments in single-molecule localization combining structured excitation and detection. So many exciting perspectives in the field!
www.nature.com/articles/s41...
Very happy to be in #ThePhotonics100 list for 2026. Big thanks to everyone in @vicidominilab.bsky.social and to all collaborators for their continuous support!
@vicidominilab.bsky.social arrived in Berlin for the single molecule workshop #ws30. Looking forward to the talks and discussions! If you're interested in the use of #spad array detectors for imaging and SM localization, don't miss the poster of my colleague Francesco tonight and my talk on Friday!
Thank you very much for your support, @vicidominilab.bsky.social! Looking forward to starting the project!
🏆🆕🇪🇺 @elislenders.bsky.social, researcher of the IIT Molecular Microscopy and Spectroscopy unit @vicidominilab.bsky.social , coordinated by Giuseppe Vicidomini, has been awarded an #ERCStG by the @erc.europa.eu
opentalk.iit.it/en/the-resea...
Grateful to my colleagues at @vicidominilab.bsky.social @iitalk.bsky.social for their support in making this research possible, and to @erc.europa.eu and #MSCA for their support! 6/6
ISM-FLUX offers more than just a simple experimental setup! Discover how the doughnut-shaped illumination provides a homogeneous localization uncertainty over a large FOV and learn about the self-calibrating procedure of ISM-FLUX. Check out our paper for all the details. 5/6
We tested ISM-FLUX on DNA-origami nanorulers, and achieved a median localization uncertainty below 5 nm for single molecules. This precision effortlessly resolved 40 nm and 20 nm nanorulers. 4/6
Similar to #MINFLUX, our localization uncertainty scales with L/sqrt(N), with L the TCP diameter and N the number of photons. However, while MINFLUX requires the emitter to be within the scanned area, ISM-FLUX has a much larger localization range, making it more robust. 3/6
ISM-FLUX makes use of a #SPAD array detector. This boosts localization range and offers flexibility in the scanned target coordinate pattern (TCP). We chose a circular pattern, enabled by galvanometric scan mirrors found in most LSMs. 2/6
Excited to share our paper on ISM-FLUX, our new #MINFLUX-based technology. Achieve sub-10 nm localization uncertainty on single molecules using a straightforward #confocal-based setup with an array detector. 1/6 www.nature.com/articles/s41...
Our last paper on s²ISM (super-resolution sectioning #ImageScanningMicroscopy) just got published on Nature Photonics @natphoton.nature.com! Discover how structured detection in laser scanning microscopes enhances both resolution and optical sectioning:
www.nature.com/articles/s41...
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