Unveiling citicoline's mechanisms and clinical relevance in the treatment of neuroinflammatory disorders Mechanisms of citicoline in treating neuroinflammatory disorders.

I read that as citicholine at first 😆 which Im interested in as it's been used for neuroinflammation. It's an OTC supplement
More info here.

faseb.onlinelibrary.wiley.com/doi/10.1096/...

I could handle that in my teens. Not now 😬
Im fussy about my no sugar tea though. It has to be Assam. PG at a pinch

I used to have 2 teaspoons of sugar in my tea and a mountain of sugar on my weetabix. The trouble with sugar is you get used to it, and it doesn't taste as sweet. Now I've got rid of the empty calories, and my mouth microbiome has improved, a spoonful of sugar tastes far too sweet to handle.

Is the system letting down people who were harmed by Covid vaccines? People affected by rare blood clots say they feel they have been airbrushed out of the pandemic.

....and its stuff like this which drowns out the fact that a small minority really do suffer from long term effects post vaccine.
The result? Research is none existent (which could be used to make vaccines even safer) and NHS has no treatment pathways
www.bbc.co.uk/news/article...

A model for propagation of RNA structural memory through biomolecular condensates Nature Cell Biology - We hypothesize that stress-induced RNA structural changes, stabilized by RNA-binding proteins in biomolecular condensates, propagate via conformational catalysis in a...

Am I completely barking up the wrong tree, or is this a possible mechanism for vaccine induced ME/CFS or PCVS?

www.nature.com/articles/s41...

Virgin Olive Oil capsules 1000mg by ECO-VITS

What the....? 😮
Just buy a bottle and drizzle a little!

No pink tax, gender tax at Aldi🙌

Case report: Manual therapies promote resolution of persistent post-concussion symptoms in a 24-year-old athlete This case report illustrates the treatment outcomes of a collegiate athlete presenting with an 18-month history of post-concussion syndrome who received a series of mixed manual therapies in isolation...

I find lymphatic /glymphatic massage and craniosacral therapy really helpful.
This case study of how it helped with post concussion syndrome is fascinating

pmc.ncbi.nlm.nih.gov/articles/PMC...

Trying to work out what caused a new reaction? Did you check stacking?
Eg sorbitol causing diarrhoea.
Apples previously fine, few cherries, no probs. That small plum.. OK , but eating all 3 in a short space of time instead of 2g sorbitol you might be eating 5-10g
Histamine can stack like this too.

The biggest risk perception is doctors who form an opinion of their patient within 10 mins without doing any tests and prescribe/refuse to prescribe based on that alone 😔

Resveratrol activation of SIRT1/MFN2 can improve mitochondria function, alleviating doxorubicin-induced myocardial injury - PubMed Doxorubicin toxicity leads to abnormal mitochondrial morphology and dysfunction in cardiomyocytes and induces apoptosis by interfering with mitochondrial fusion. Resveratrol ameliorates doxorubicin-in...

Came across this recently. I know some people find Reservatrol useful, so this might be partly why.
pubmed.ncbi.nlm.nih.gov/38089747/

"The metabolics of x are really interesting " comment can often prompt HCPS to think a bit harder without the qualification card 😁

Gently flowing river through a wood bathed in soft May sunlight , with reflection of the trees on the water

On reflection , I like forest bathing 🥰

Parkinson's: Could changes in speech be an early sign? Changes in speech and voice might be the first sign of Parkinson's disease, according to an algorithm designed to facilitate early diagnosis.

Parkinsons can be detected through voice.
This is definitely the case with the people I know who became more softly spoken, eventually needing physio to help with speech in the latter stages
www.medicalnewstoday.com/articles/alg...

It seems I'm eating pretty close to what Novak Djokovic eats. Athletes benefit from anti-inflammatory diets, too.

www.gq.com.au/health/welln...

Rising health-related benefit claims not linked to NHS waiting lists The Government has announced a series of welfare reforms to get people back into work

"Benefit claimants themselves say there are many other factors preventing them from finding paid work, such as that work would make their health condition worse, it is difficult to travel and their health condition fluctuates too much" No mention of covid 🤔
www.independent.co.uk/health-and-w...

Awwh, thank you. The boys have been brilliant and adapted to my slower pace of life. Wouldn't be without them.

I mix powder with non dairy yoghurt, and drink is separate. Might work better for you if you don't want to waste the powder.

Wow. That's quite marked. Deffo something off that needs further investigation

Look at that bounceback ability 😍 I reckon this is the first sign of going from moderate to mild. You get to know what your body can do and relatively quickly return to resting HR. Be very careful if HR rises slightly with a bug. It really throws it off.

Do it next to something soft x 😬

The Fukuda step test, randomly appeared on my feed. It can be used to investigate vestibular migraine. So weird after seeing you mention it.
Some info here if you're not aware.
horizontbi.com/fukuda-stepp....

“Nattokinase as a potential therapeutic agent for preventing blood-brain barrier dysfunction in neurodegenerative disorders” Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are characterized by progressive destr…

Another reason to consider Nattokinase
www.sciencedirect.com/science/arti...

My preference is Tibetan singing bowls. Listening to them fade in and out, blocks out everything else. I use UCLA Mindfulness free App. There's a short one on the App and a longer one on one of their Podcasts (also free)

Military Pain Medicine: Sustaining the Fighting Force ABSTRACT. Active duty military service members (ADSMs) suffer disproportionately from chronic pain. In the USA, military pain physicians serve an important

I'm sure a lot of this stuff is adapted from military pain management where either pain relief isn't available or isn't appropriate (opiods) in a war zone. This article makes interesting reading and mentions stellate ganglion block for PTSD 🤔
academic.oup.com/milmed/artic...

'My peanut allergy nearly killed me - now I eat them every day' Just a few years ago, Chris Brookes-Smith could have died from eating peanuts - but taking part in a clinical trial has changed his life.

The mechanisms of this type of reduced reaction must surely have wider implications for immune dysfunction and MCAS. It works for some and not others also sounds familiar
www.bbc.co.uk/news/article...

Copper would be interesting. There's loads of reasons it might be low in chronic illnesses, such as chronic inflammation and immune dysfunction. Low copper can mimic some symptoms such as fatigue, weakness, and neurological problems. My GP said he couldn't test for it 🤷‍♀️

It sounds horrendous. I really hope you get some answers that can be treated 🤞🏻

It's a great idea but it would need volunteers to be vetted somehow. It would only need one bad apple to ferment and seed distrust

If you compare LC and other post viral illnesses to illnesses with successful research and subsequent treatments like HIV, it's a very poor cousin. Very disabling but doesn't kill=less urgency, no decent biomarker and has subsets=less targeted research, advocacy is watered down by media response...