Scientists at @pmresearch-uhn.bsky.social have developed CellNEST, a powerful AI tool that maps how cells talk to each other. By detecting complex signals between cells, it could lead to new ways to target tumours and stop disease progression.

🔗 www.uhnresearch.ca/news/pinpoin...

25.07.2025 15:16 — 👍 3    🔁 2    💬 1    📌 0

🔍 Cancer Cells Relay Messages to Coordinate the Spread

CellNEST, an AI-powered tool developed by Dr. Gregory Schwartz's team @uhn.ca, found that cancer cells relay messages in a "two-hop" fashion, fuelling the progression of #PancreaticCancer.

In Nature Methods:
www.nature.com/articles/s41...

17.06.2025 13:40 — 👍 4    🔁 3    💬 0    📌 0

Out today from the Schwartz lab! A new way to study cell-cell communication from spatial transcriptomics data. Cell Neural Networks on Spatial Transcriptomics (CellNEST) can detect both signals between individual cells and relay networks of communication. www.nature.com/articles/s41...

06.06.2025 17:32 — 👍 7    🔁 2    💬 0    📌 0

CellNEST's architecture enables finding patterns of signals, potentially detecting relay networks of communication. This work was made possible by the fantastic Fatema Zohora, Deisha Paliwal, Joshua Li, Victoria Gao, Eugenia Flores-Figueroa, and Faiyaz Notta!

06.06.2025 14:28 — 👍 0    🔁 0    💬 0    📌 0

We are proud to announce the publication of CellNEST, deep-learning detection single cell-cell or even "relay" communication on #SpatialTrascriptomics data at single-spot or #SingleCell!

Paper: nature.com/articles/s41...

Code: github.com/schwartzlab-... and github.com/schwartzlab-...

06.06.2025 14:26 — 👍 1    🔁 0    💬 1    📌 0