Dervis Salih

I think we might have been stood together. It was generally very well natured. But a small group of tall men pushed in late, and were pushing in front of everyone else, whether women or shorter folk. And then patronising people.

Well that was a great idea, a stage organised by @johnkennedydj.bsky.social @radiox.co.uk @themaccabees.bsky.social @allpointseastfest.bsky.social #AllPointsEast featuring Man/Woman/Chainsaw amongst others

The calm before the storm @themaccabees.bsky.social @allpointseastfest.bsky.social @radiox.co.uk #AllPointsEast #Maccabees

Excited to share my new book with you. Out now for pre-order: www.penguin.co.uk/books/458539...

Redox Dyshomeostasis Links Renal and Neuronal Dysfunction in Drosophila Models of Gaucher and Parkinson's Disease Gaucher disease (GD), the most common lysosomal storage disorder, is caused by bi-allelic mutations in the GBA1 gene. Variants in GBA1 also represent the most frequent genetic risk factor for Parkinso...

New from the Kinghorn Lab! 🧠🔬 Our latest preprint shows that in fly 🪰🧬 Gaucher’s & Parkinson’s 🧠 models, kidney dysfunction drives neurodegeneration - supporting emerging links between renal health & Parkinson's. You can read it here:
www.biorxiv.org/content/10.1...

YouTube video by Dementia Researcher Blood Biomarkers & Testing for Alzheimer’s Disease

Blood Biomarkers: Testing for Alzheimer’s Disease

Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.

Recorded at the Wessex Dementia Research Conference

youtu.be/3fLl1Mzwbsk

Work Experience Greensmith Lab 2025

Another fulfilling week for The Greensmith Lab (+ colleagues from other DNMD groups) hosting their annual Work Experience at UCL QSIoN. The Summer Students were able to get a taste of scientific life, with hands-on experience, learning key skills eg. pipetting, cell culture, immunostaining and more!

Congratulations to all colleagues that have worked hard to support the scientific community, and that have been recognised for their efforts. Senior Academic and Early Career Promotions 2024-25 | UCL Faculty of Brain Sciences @uclqsion.bsky.social www.ucl.ac.uk/brain-scienc...

a yellow sign that says we 're hiring ALT: a yellow sign that says we 're hiring

Spread the news! We are excited to expand our research team, working on cellular senescence, at the Cancer Research UK Cambridge Institute, University of Cambridge.

jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/

Cerebral small vessel disease (cSVD) can cause stroke and dementia, but has no cure. With @ukdri.ac.uk, we're supporting a clinical study at @imperialcollegeldn.bsky.social to test whether XBD173, a shelved anxiety drug, can reduce brain damage in people with cSVD.

It's cool to live in a country when the Women are better at football than the men #WEURO2025 #Lionesses #EnglandItaly

New preprint. ATF4 activation is thought to lead to longer lifespans. However, our study shows that suppression rather than activation extends lifespan in the fly. New Qs: how we can target ATF4 or its downstream targets to gain targeted longevity benefits.
www.biorxiv.org/content/10.1...

Nonuniversality of inflammaging across human populations - Nature Aging Analyzing readouts of inflammaging across four cohorts, Franck and colleagues identify strong variation and observe that inflammaging, in its known form, primarily emerges in industrialized—but not no...

Nonuniversality of inflammaging across human populations
www.nature.com/articles/s43...

"Age is just a number, attitude is everything" Fauja Singh is world's oldest marathon runner, & local and national hero and inspiration. Took up running at age of 89 against grief of losing his wife and son. Raised thousands of pounds for charity www.itv.com/news/2025-07...

Research Assistant: PALLDEM-Homecare project Research Assistant position at King’s College London. Join the PALLDEM-Homecare project to support homecare for people with dementia.

Research Assistant position at King’s College London. Join the PALLDEM-Homecare project to support homecare for people with dementia. Qualitative research skills required. Closing date: 27th July

www.dementiaresearcher.nihr.ac.uk/job/research...

The pick of the London festivals @themaccabees.bsky.social ##AllPointsEast Now with @johnkennedydj.bsky.social @radiox.co.uk stage

Dementia Researcher Community - Working with Difficult People: Strategies for Academic Settings Dementia Researcher Community - Working with Difficult People: Strategies for Academic Settings

Working with tricky colleagues? Join us at 12pm BST on Weds 16 July for tips on handling conflict in research with Dr Claire Price & Dr Anna Mallach. Live talk & chat.

communities.dementiaresearcher.nihr.ac.uk/c/events/wor...

Amazing opportunity postdocs

What is the link between rugby and dementia?

A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL

Unravelling the plasma proteome: Pioneering biomarkers for differential dementia diagnosis INTRODUCTION Diagnosing Alzheimer's disease (AD) is challenging due to overlapping symptoms with other dementias and the invasiveness of current biomarkers. This study introduces the NULISA platform...

Happy to have played a small part in testing this next generation of blood biomarker tests across different dementias: Unravelling the plasma proteome: Pioneering biomarkers for differential dementia diagnosis alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Research Assistant: AAV gene therapy project Research Assistant at University College London, Join Prof Joanne Ng’s team on a gene therapy project for Parkinson’s, using in vivo models of neurodegeneration

Research Assistant at UCL Institute of Neurology, London. Join Professor Joanne Ng’s team on a gene therapy project for Parkinson’s, using in vivo models of neurodegeneration. Closing date: 20th July

www.dementiaresearcher.nihr.ac.uk/job/research...

Saucony London 10K 2025 Help The National Brain Appeal raise money to support The National Brain Appeal

Professor Mike Hanna will be leading the UCL IoN CNMD Team in fundraining for @BrainAppeal in the Saucony London 10K race on July 13, 2025. Please donate what you can!
www.justgiving.com/page/the-nat... Please repost/share

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis - Molecular Neurodegeneration Background Mutations in PSEN1 cause familial Alzheimer’s disease with almost complete penetrance. Age at onset is highly variable between different PSEN1 mutations and even within families with the sa...

It's out!

More than just making amyloid?
What if mutations in PSEN1 also predispose inflammation.

We asked if Alzheimer's disease mutations affect cytokine signalling using stem cell derived astrocytes. molecularneurodegeneration.biomedcentral.com/articles/10.....

Five ways to reduce cholesterol, blood pressure and dementia risk in 20 minutes A professor of neurology and chief medical officer at Alzheimer's Research UK, has outlined easy ways to give your brain a boost this summer

In this interview with the @dailyrecord.co.uk, Professor @jmschott.bsky.social (@uclqsion.bsky.social) shares six top tips to boost your brain health. 🧠 ✨

First post on Bluesky—
We identify two IFN-inducible lncRNAs as endogenous MDA5 ligands forming an RNA–sensor feedback loop that sustains innate immunity.
m⁵C + ALY/REF = cytoplasmic targeting switch

Read more www.researchsquare.com/article/rs-6...

#InnateImmunity #lncRNA #MDA5 #Autoimmunity

YouTube video by UK Dementia Research Institute - UK DRI Stem Cell Models of Neurodegeneration 2025

Amazing to bring researchers from around the world together with CURE-ND for the first Stem Cell Models of Neurodegeneration (SCMND) Conference in Edinburgh earlier this year 🧠

Video round-up 📽️ youtu.be/9wMRndMVbQM?...

Conference blog 👉 www.ukdri.ac.uk/news-and-eve...

Jonathan Pryce On the Tragedy of Dementia in ‘Slow Horses’ The character of David Cartwright on Apple TV+'s Slow Horses wouldn't have the humanity he has without the brilliant input

1- In "Slow Horses," Apple TV+ series based on Mick Herron's novels, Jonathan Pryce sensitively depicts a retired spy who has developed #dementia.

He drew on his experience playing similar roles & serving as an ambassador for the UK Alzheimer’s Society.

thecontending.com/jonathan-pry...

When this WhatsApp arrives on a Sunday eve with no explanation it can only mean be thing… your US co-convener has arrived & Molecular Neurodegeneration starts tomorrow! Excited to meet this years cohort 🧬 🧫 🧪

Postdoc Research Assistant: Mechanisms of the C9ORF72 Join Dr Arpan Mehta's lab at MRC PPU, University of Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons.

Join Dr Arpan Mehta's lab at MRC PPU, Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons. Closing date: 18th July

www.dementiaresearcher.nihr.ac.uk/job/postdoc-...