Gavin McStay

What a lovely endorsement, thanks Alison!
It was a pleasure to host you and your talk was FASCINATING! I'm still thinking about mumia....

It was a great pleasure to be invited to the @mymitomission.bsky.social annual meet-up this past weekend. A wonderful community trying to make things better for #mitochondrial_disease. I took part in a panel discussion, did an interview, did some #mitochondria origami and had lots of fun 🤩

In the footsteps of giants - BBC News One of the longest sets of dinosaur footprints in the world has been discovered in a limestone quary near Bicester, in Oxfordshire, England.

Our speaker from earlier this year, @peterfalkingham.com, is part of a team that found one of the longest #dinosaur track ways in the world www.bbc.co.uk/news/resourc...

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...

Fresh selection of papers on #MitochondrialDisease from #week41! 📚 💚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
www.science.org/doi/10.1126/...

Time to talk mitochondria and test out the origami #mitochondria With @mymitomission.bsky.social Thanks to the #biochemistry students who constructed the mitochondria and ATP synthase @origamiorganelles.bsky.social

Cell-selective multiplexed bioorthogonal noncanonical amino acid tagging for nascent proteomics - Nature Chemical Biology Engineered aminoacyl-tRNA synthetase (aaRS) mutants have been developed that facilitate ultrafast bioorthogonal noncanonical amino acid tagging (BONCAT) of newly synthesized proteins in diverse bacteria, including ESKAPE pathogens. The substrate polyspecificity of the aaRS mutants enables pulse-chase BONCAT and differential tagging of temporally distinct nascent proteomes in cells.

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/... #ELMs
via @biomednews.bsky.social

includes research on: chemical biology for nascent proteomics (h/t @achemsynbio.bsky.social), designer protein materials (h/t @natmater.nature.com) & more 🧪

a stack of books with one titled palace curiosities on top ALT: a stack of books with one titled palace curiosities on top

This week we have a great selection of novel computational and analytical methods for metabolomics and lipidomics.

biomed.news/bims-metlip/...

A collaboration with @biomednews.bsky.social

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function - Nature Metabolism Saber et al. show that the lipase DDHD2 provides endogenous saturated fatty acids to support fatty acid oxidation and energy production, proteostasis and membrane trafficking balance.

#MitochondrialDisease papers from #week40! 📚 💚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

A few highlights below! 👇

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function
www.nature.com/articles/s42...

It is a real pleasure to share papers on interplay between viruses and host metabolic an redox systems, published during last two weeks:
biomed.news/bims-mevinf/...
biomed.news/bims-mevinf/...

Many thanks to Biomed.news, @gavinmcstay.bsky.social and Thomas Krichel.

I direct the free biomedical research literature discovery platform @biomednews.bsky.social. Perhaps you or your network would be interested in using it as an alternative. You can sign up to curate a report here biomed.news/open_a_report or subscribe to existing reports here biomed.news/reports

I direct the free biomedical research literature discovery platform @biomednews.bsky.social. Perhaps you or your network would be interested in using it as an alternative. You can sign up to curate a report here biomed.news/open_a_report or subscribe to existing reports here biomed.news/reports

I direct the free biomedical research literature discovery platform @biomednews.bsky.social. Perhaps you or your network would be interested in using it as an alternative. You can sign up to curate a report here biomed.news/open_a_report or subscribe to existing reports here biomed.news/reports

I direct the free biomedical research literature discovery platform @biomednews.bsky.social. Perhaps you or your network would be interested in using it as an alternative. You can sign up to curate a report here biomed.news/open_a_report or subscribe to existing reports here biomed.news/reports

Ribonucleotide incorporation into mitochondrial DNA drives inflammation - Nature Imbalanced nucleotide metabolism leads to age- and mtDNA-dependent inflammatory responses and senescence-associated secretory phenotype in senescence.

#MitochondrialDisease papers from #week39! 📚 👇
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social

A few highlights below!

📢Last weeks #immunometabolism discoveries
@biomednews.bsky.social ⬇️⬇️⬇️

biomed.news/bims-imicid/...

Highlights:
Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.

a cartoon of a girl carrying a stack of books with the website bibliotheca.com written below her ALT: a cartoon of a girl carrying a stack of books with the website bibliotheca.com written below her

Here are the highlights for the most recent computational and analytical methods for small molecule analysis coupled to mass spectrometry.

biomed.news/bims-metlip/...

A collaboration with @biomednews.bsky.social

Hong et al, Cryo-EM structure of the prohibitin complex in open conformation https://www.pnas.org/doi/10.1073/pnas.2512430122

To honour the #MitochondrialDisease #AwarenessWeek 💚 we bring a new collection of recently-published research papers related to mitochondrial disease:
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

Cryo-EM of the prohibitin complex

Engineered prime editors with minimal genomic errors - Nature Engineered prime editor systems with reduced occurrences of unwanted insertions or deletions during genome editing are developed.

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/... #ELMs
via @biomednews.bsky.social

includes research on: engineered prime editors, dECM hydrogels, mRNA-loaded lipid nanoparticles, aspiration-assisted bioprinting (AAB) & more 🧪

Good Sunday, all. This week has seen some beautiful papers in #cancermetabolism and #mitochondrialbiology. Don't miss the curated summary, find it here:

biomed.news/bims-camemi/...

@biomednews.bsky.social #keepreading 💥 📚

"The real meditation is how you live your life."-Jon Kabat-Zinn

New spirit protein identified - Cavin1 - replacing Gravin www.genecards.org/cgi-bin/card...

Next level - doing a Bradford assay in Bradford

Here is a short article about my contribtuions to the @biochemsoc.bsky.social. They have supported me since I started my PhD 20 years ago and I am very happy to contribute to their activities www.biochemistry.org/about-us/new...

A biochemistry first for me - doing a Bradford assay with someone from Bradford #protein #biochemistry

⏱️ ONE WEEK LEFT!
Travel Grants available for the FEBS Workshop on Aging in Hematopoiesis that will take place in Crete on October 20-24, 2025!
Phenomenal speakers, beautiful location & lots of opportunities to network!

⏱️ Deadline for applications: July 31. To apply ▶️: buff.ly/C1Ar5Sx

🩸 Register today for the FEBS Workshop on Aging in Hematopoiesis that will take place in ☀️ Crete on October 20-24, 2025!

🩸 An outstanding scientific program in a beautiful location! More info: buff.ly/bSHhzR3

FEBS Press Although publication in scholarly peer-reviewed journals remains the gold standard for communication of findings in the life sciences, the gold has been debased by various impurities. Here, I discuss....

An interesting read about the publication process in life sciences in @febsletters.bsky.social

Five problems plaguing publishing in the life sciences—and one common cause - Wright - 2024 - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/...

🔉Last weeks #immunometabolism discoveries @biomednews.bsky.social 🔽🔽🔽

biomed.news/bims-imicid/...

Highlight:
Macrophage metabolic reprogramming during dietary stress influences adult body size in Drosophila

Maydell et al, ABCA7 variants impact phosphatidylcholine and mitochondria in neurons https://www.nature.com/articles/s41586-025-09520-y

Starting the #MitochondrialDisease Awareness Week with a new collection of papers from #week37! 📚 💚 🤍
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

Highlights
ABCA7 variants impact phosphatidylcholine and mitochondria in neurons

What an incredible start to the British Science Festival in Liverpool 🎉

Over the past three days science has taken over our city as we co-host the festival with University of Liverpool.

There’s still time to sign up to the free events happening this weekend.

➡️ www.ljmu.ac.uk/about-us/new...

YouTube video by Face Lab LJMU Digital avatar of King Richard III

Yesterday evening @facelabljmu.bsky.social brought to us the digital avatar of King Richard III delivering an address
detailing the conferment on his son, Edward, of the offices of Prince of Wales and Earl of #Chester youtu.be/FbH_KLMs6aY?...