Jon Epstein

Just published @science.org
Engineering T cells within the body, a big step forward for treating cancer and autoimmune diseases, as demonstrated in animal models. Uses the mRNA + nanoparticle platform
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

Trump Has Cut Science Funding to Its Lowest Level in Decades The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.

www.nytimes.com/interactive/...

Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—from decades of NIH funded research
www.nejm.org/doi/full/10....
@nejm.org
www.nejm.org/doi/full/10....
www.nytimes.com/2025/05/15/h...

First Patient Treated with Personalized CRISPR Therapy, Developed in Just Six Months The first on-demand CRISPR therapy for an infant with a rare metabolic disease developed by the IGI and collaborators around the world.

This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on!

innovativegenomics.org/news/first-p...

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com/2025/05/15/h...

The Lead CNN on X: "Cancer survivor warns against threats to health funding Watch the full video here: https://t.co/1uPBOFkahY https://t.co/ckKr5wUY8U" / X Cancer survivor warns against threats to health funding Watch the full video here: https://t.co/1uPBOFkahY https://t.co/ckKr5wUY8U

x.com/theleadcnn/s...

Emily Whitehead and her father on CNN with Jake Tapper speaking to the value of science. She is alive thanks to CAR T therapy developed at Penn and CHOP.

Duck confit tonight with rice and Swiss chard and a plumb sauce made from fresh plumbs, soy sauce, Mirin, garlic, scallions, cayenne and ginger, garnished with scallions. Served with a California Syrah/Grenache. 🍜🍽️

#food 🍜

Asparagus and Gruyère soufflé tonight. My idea but @maggymyers (“The Commish”) execution. Béchamel sauce with roasted asparagus, whipped egg whites and grated Gruyère with a few chopped chives. Served with a Beaujolais Nouveau.

Reposting a favorite to bsky #food:

Lobster Thermidor. Sauce made with shallots and freshly foraged Chanterelles, a touch of mustard, lobster reduction, white wine and cream. Topped with Parmesan and parsley. Served with a Sancerre Rose. 🍜

Fresh baguettes tonight, in preparation for the Eagles. Served with D’Affinois cheese, Boursin, an olive tapenade and some leftover Cabernet Sauvignon. Go Birds! 🦅🦅(And what a crazy Washington-Dallas game!)

My first bsky pasta post. Homemade linguini with artichoke hearts, roasted red peppers and green olives in a white sauce made with wine, shallots, garlic. Served with a Sancerre rose.