🔬Revelan factores potencialmente claves en la resistencia al daño de las células cancerosas
👩🔬Un equipo del @cbm-csic-uam.bsky.social ha identificado factores que amenazan la supervivencia celular cuando falla la vigilancia, como ocurre en los tumores
➡️ http://tiny.cc/tves001
11.09.2025 08:03 — 👍 4 🔁 5 💬 0 📌 0
@cabimer.bsky.social @unisevilla.bsky.social @cbm-csic-uam.bsky.social @crick.ac.uk
31.07.2025 16:29 — 👍 0 🔁 0 💬 0 📌 0
🧬 Checkpoint mutants undergo gradual degradation of nascent DNA at replication forks, which is prevented in the absence of Rad51, Mus81, Rad5 and Exo1
🧪 Heterologous expression of human PrimPol or overexpression of Mre11 can counteract the aberrant processing of replication forks
31.07.2025 16:28 — 👍 0 🔁 0 💬 1 📌 0
📄 We identified Rad51, Mus81 and Rad5 to be involved in the irreversible replication fork arrest observed in yeast checkpoint mutants upon DNA damage, despite they are also required for normal fork progression or restart once the damage is removed
31.07.2025 16:26 — 👍 0 🔁 0 💬 1 📌 0
S-phase checkpoint protects from aberrant replication fork processing and degradation
Abstract. Replication stress, a hallmark of cancer cells, is detected by checkpoint mechanisms that trigger a range of cellular responses. Among these, the
Excited to share my first PhD paper published in @narjournal.bsky.social! This project was led by amazing supervisor Belén Gómez González in @aguilerloop.bsky.social lab. Thanks to all colaborators of Blanco and Diffley teams. I hope you like it!
Now online here 👇🏼 academic.oup.com/nar/article/...
31.07.2025 16:25 — 👍 8 🔁 3 💬 1 📌 0
Glad to see our PACT preprint published in @naturecomms.bsky.social!
"Cooperative role of PACT and ADAR1 in preventing aberrant PKR activation by self-derived double-stranded RNA"
Another step forward in understanding innate immunity. @buissonlab.bsky.social
🔗 www.nature.com/articles/s41...
07.04.2025 17:21 — 👍 2 🔁 1 💬 0 📌 0
Interested in metals and cyanobacteria, in any order. Based @IBVF_Sevilla, Universidad de Sevilla/CSIC. Views my own.
https://www.ibvf.us-csic.es/grupos-investigacion/stress-response-and-synthetic-biology-of-photosynthetic-microorganisms/?lang=en
Nucleic Acids Research (NAR), from Oxford University Press, publishes the results of leading-edge research into physical, chemical, biochemical and biological aspects of nucleic acids and proteins involved in nucleic acid metabolism and/or interactions
Centro Andaluz de Biología Molecular y Medicina Regenerativa.
Visítanos en https://youtube.com/@CentroCabimer
Geneticist and cell biologist at the University of Southern California | DNA repair | heterochromatin | recombination | nuclear dynamics | nuclear architecture | genome stability.
International research centre devoted to curing #cancer and other diseases linked to #aging. @cerca.cat center, member of @bist.eu.
www.irbbarcelona.org
Post doc and manga lover, I will be sharing science-related stuff and manga reads.
Postdoc in M. Pagano Lab at NYU | PhD with V. Costanzo at IFOM/SEMM/UniMi | DNA replication stress & DNA repair aficionado
#DNA repair, #Chromatin, #PARP, #Fluorescence #Microscopy and more in #Rennes
Postdoc, Harvard University. #DNArepair
Postdoc at Masaryk University, Brno, Czechia | Advanced microscopy, Single-molecule biophysics, Telomeres, Genome maintenance.
Junior Group Leader at @CICancer. Cell Biologist. Enthusiastic of Cell Division and Chromosome Segregation.Omnis cellula e cellular. #Mitosis and #Endomembrane.
https://www.cicancer.org/grupo?id=88
#Ph.D. Biological Sciences #Cancer_Biologist, #DNA_Damage_Response, #Nucleic_Acids_Research #CSIR-Indian Institute of Chemical Biology, Kolkata, India
PI at University of Seville, cell biology dept. Spain 💃🏻. Chromosomal instability and cellular plasticity mostly in cancer. #newPI
https://www.departamento.us.es/dbiocel/investigacion/ingeplascecan.htm
Post doc 🧬👩🏻🔬👩🏻💻 in @thecesarelab.bsky.social at @cmri.bsky.social | using insights from epigenetics and genome stability to improve pediatric cancer treatment | Optimist 😊 | Runner 🏃🏻♀️ | Wife & Mum 💛🌻
Postdoc in the Boulton Lab at the Francis Crick Institute. Currently working on dna damage.
Assistant professor at the University of Minnesota studying how host-microbe interactions impact genome integrity.
langlab.info
Assistant Professor, BMB @ SLU SOM. Former Postdoctoral Fellow @ Vanderbilt University and PhD student @ University of Saskatchewan
Associate Professor @ UW-Madison Biochemistry. www.limlab.org
Telomeres, Cryo-EM, Single-molecule Biophysics. Opinions are my own. 🇸🇬
Ph.D. Candidate Cancer Bio | Quant Bio.
Unraveling Chromosomal Instability & Aneuploidy in tumor. 🧬👩🔬🧫
@McArdleLab UW-Madison
Dog lover, Yoga enthusiast, Hiker
