Achyut Bora's Avatar

Achyut Bora

@achyutbora.bsky.social

#Ph.D. Biological Sciences #Cancer_Biologist, #DNA_Damage_Response, #Nucleic_Acids_Research #CSIR-Indian Institute of Chemical Biology, Kolkata, India

168 Followers  |  211 Following  |  4 Posts  |  Joined: 18.11.2024  |  1.3732

Latest posts by achyutbora.bsky.social on Bluesky

Preview
Disrupting the Base Excision Repair (BER) Pathway by Targeting the Abasic Site Enhances the Sensitivity of PARP Inhibitor in HR-Proficient Cancer Cells Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) are clinically effective in homologous recombination (HR)-deficient cancers but have limited efficacy in HR-proficient cancers; therefore, new st...

Published: My recent research on PARP inhibitors in BRCA1/2-proficient cancers, featured in ACS Chemical Biology journal. #cancerresearch #dnadamage ACS Publications | @pubs.acs.org pubs.acs.org/doi/full/10....

22.07.2025 16:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image

Iโ€™ve finally successfully defended my PhD thesis and am now stepping into the next phase of my journey๐Ÿ‘จโ€๐ŸŽ“๐Ÿ™‚. I am grateful to everyone who has been a part of my journey๐Ÿ™๐Ÿ™ (CSIR-Indian Institute of Chemical Biology, Kolkata) #csir_iicb #AcSIR_India #PhD #Doctorate_Journey #Cancer_Biology #DDR

04.01.2025 18:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The research highlights targeting DNA abasic sites (loss of a base in dsDNA) to enhance the efficacy of temozolomide, a commonly used alkylating agent, in cancer treatment. #cancerresearch #abasic_sites #DNA_damage_response

19.11.2024 13:25 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Published our research work in the NAR Cancer Journal;

DNA abasic sites act as rational therapeutic targets to synergize temozolomide response in both MMR-proficient and deficient cancer
academic.oup.com/narcancer/ar...

19.11.2024 13:24 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@achyutbora is following 20 prominent accounts