Amit K Dash, PhD

Meet the 2025 Laureate Award Winners - Endocrine News For more than 80 years, the Endocrine Society has recognized the achievements of endocrinologists worldwide. The Laureate Awards recognize endocrinologists for seminal research, meritorious service, l...

Today we honor @danieljdrucker.bsky.social at #ENDO2025, for being our Fred Conrad Koch Lifetime Achievement Award recipient, our highest honor that recognizes lifetime achievements and exceptional contributions to the field of #endocrinology: bit.ly/4l7fbEW

@endocrinenews.bsky.social

NIH announces end to funding for animal-only studies - Drug Discovery and Development Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.

www.drugdiscoverytrends.com/nih-announce...

FDA Authorizes First AI Platform for Breast Cancer Risk Prediction | Docwire News FDA authorizes CLAIRITY BREAST, the first AI tool to predict 5-year breast cancer risk from screening mammograms.

The FDA has granted De Novo authorization for CLAIRITY BREAST, a new first-in-class platform that predicts a woman’s future 5-year #breastcancer risk from routine screening mammography images using an artificial intelligence (AI) model
www.docwirenews.com/post/fda-aut...

Multilayered Mechanisms for Long-range Regulatory Interactions in Eukaryotic Transcription Transcription is a fundamental biological reaction that underlies essentially all developmental and physiological processes across species. While subs…

The multilayered actions of #enhancers and associating regulatory DNAs, such as facilitators and Range Extenders, dynamically modulate the clustering of transcription machineries to flexibly control the dynamics of #geneexpression during development

www.sciencedirect.com/science/arti...

Chemotherapy awakens dormant cancer cells in lung by inducing neutrophil extracellular traps - PubMed Disseminated tumor cells (DTCs) can remain in a non-proliferative, dormant state for years in distant organs, but the exogenous causes triggering their reactivation and metastatic colonization are unc...

A recent thought-provoking study reported that chemotherapeutic drugs, such as doxorubicin and cisplatin, enhance the proliferation and lung metastasis of dormant #breastcancer cells by facilitating the formation of neutrophil extracellular traps (NETs).

pubmed.ncbi.nlm.nih.gov/40614736/

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer Androgen receptor (AR) signaling inhibitors, including enzalutamide, are treatment options for patients with metastatic castration-resistant prostate …

A nice informative work from Drs. Wilbert Zwart and Andries M. Bergman's group identified a distinct subset of H3K27ac-differentially marked regions associated with treatment responsiveness in #mCRPC through epigenetic profiling of #enhancer/promoter activities.
www.sciencedirect.com/science/arti...