Constantin Pape

Interested in applying for an ERC, Emmy Noether, or local AI research group this year? Join our info call! I will also be there ;).

Early career researcher: Are you thinking about writing an ERC , Emmy Noether Proposal, or Lower Saxony AI Group application, and are you interested to work with us at @uni-goettingen.de and @goettingen-campus.de

Research Software Engineer - Spatial-omics The Oliver Stegle team and the Bioimage Analysis Support Team at EMBL Heidelberg are looking for a research software engineer to contribute to the development and maintenance of highly-used open-sourc...

We are hiring a Research Software Engineer to enhance and maintain the SpatialData framework.

We will work together with colleagues at EMBL, DKFZ, GSK, and across the scverse community.

🔗 Deadline: 15/02/2026
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

https://doi.org/10.5281/zenodo.14762435 https://bsky.app/profile/falk-illustrations.de

AMAZING JOB OPPORTUNITY ALERT!!!

@calm-stp.bsky.social is hiring a Data & Systems Steward! 🧬

🔹Manage #bioimage data & #OMERO admin
🔹Automate via #Python/#Bash
🔹Support #FAIR principles
🔹Work closely with @crick-ia-team.bsky.social

⏰ Deadline: 08 Feb 2026

Apply: www.crick.ac.uk/careers-stud...

🚨 Only a few days left to apply for maybe the best microscopy course there is!!! 🚨
👇👇👇👇👇👇👇👇👇👇👇

We are excited to share that we are hosting a hands-on course on "Electron Microscopy of Marine Environmental Samples" 🔬🌊
📍Naples, Italy 🗓️ 8th-11th of April 2026
If you are interested, check the program below!
Registration is open until the 12th of February. We look forward to seeing you there!

Deep Learning for Microscopy Image Analysis Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

🚨 Alarm!!! 🚨
AI/ML course for microscopy image analysis!!! 🧐
In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!?

20 students, ~14 TAs and lecturers
🗓️ June 4-18 2026

✍️ Jan 15 2026 ✍️

🔁 pls!!

www.janelia.org/you-janelia/...

🔬 We're hiring a Junior Group Leader for Data-Driven Digital Twins/System Models in medicine/life sciences at @uni_goettingen! Perfect opportunity for early-career researchers who want to:
- Lead their own research group
- Work at the intersection of AI, simulation, and biomedicine

🧠🪰 The adult Drosophila brain connectome now gives us a complete wiring diagram of ~140k neurons. But a wiring diagram alone isn’t understanding.

How is this massive network organized?

Our paper tackles that question by mapping community structure across the entire fly brain. 1/

📣 Paper alert: We present dense attentive probing (DeAP), a method to measure the representation quality of various vision backbones for dense prediction tasks. It uses small, parameter-efficient readouts with learnable masks to generate dense predictions from backbone features of any size.

We’ll be at @neuripsconf.bsky.social on Wednesday, 3 December, from 11 a.m. to 2 p.m. (San Diego time). Come and chat with us about why distance matrices and invariances are cool! 🎉 #InterdisciplinaryML #neurips2025 #bioimageanalysis #shapequantification

Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41...
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)

📢 Paper alert 📢

Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:

doi.org/10.1038/s415...

Here comes a 🧵 ... (1/9)

🔬 Exciting PostDoc Opportunity! 🐁🧠

We - the @sinzlab.bsky.social (sinzlab.org) and @trose-neuro.bsky.social (troselab.de) Labs - are seeking an experimental postdoc to work at @unibonn.bsky.social with cutting-edge miniature 2-photon microscopy and gaze tracking in freely behaving mice.

BigVolumeBrowser: a new 3D multi volume/mesh/point clould (SMLM) data viewer Hello everyone, I’d like to share with you another 3D viewer for FIJI, BigVolumeBrowser (full documentation link). It‘s a first initial public release, so there is still space for improvements. Le...

Finally, the first public release of #BigVolumeBrowser, so after teasers, you can try it yourself. For details, please check the announcement post (1/2)
forum.image.sc/t/bigvolumeb...

Studying cochlear neuroanatomy demands imaging the entire cochlea at subcellular resolution. In our recent study (tinyurl.com/isotropicLSFM), we recorded the cochlea at isotropic resolution across the whole organ, laying the groundwork for what follows…

#lightsheet
#isotropic
#cochlea

This work is nicely summarised by @cppape.bsky.social:
bsky.app/profile/cppa...

🧬 10 @dfg.de-funded PhD positions at @goettingen-campus.de 🧬
❗Focus: Evolution of gene regulatory networks & Wnt signaling in emerging models (insects, snails, flatworms, cnidarians).
💻 Methods: 'Omics, Bioinformatics, CRISPR/RNAi & Imaging.
📌Start: June 2026.
#EvoDevo #Genomics #Bioinformatics

Python package managers: uv vs pixi? When I talk to people about Python package management in 2025 I see the following tools in active use; uv, pixi, pip, conda, mamba, micromamba and poetry. There may be others, but I don’t hear much ab...

For Python package management I use a mixture of pixi, uv and conda depending on the task I'm doing.

I wrote up a long form post about the history of these tools, why each one exists, and why I settled on these choices in my workflow.

jacobtomlinson.dev/posts/2025/p...

GitHub - computational-cell-analytics/cochlea-net: Deep learning-based image analysis for cochleae imaged in light-sheet microscopy Deep learning-based image analysis for cochleae imaged in light-sheet microscopy - computational-cell-analytics/cochlea-net

This work was an excellent contribution with the group of Tobias Moser, building on the cutting edge light-sheet microscopy of @huiskenlab.bsky.social. Special thanks to Lennart, Aleyna, Elisabeth, and Martin!
If you want to use CochleaNet, check out github.com/computationa...

We comprehensively evaluate our method and then use it to analyze the morphlogy of intact mouse and gerbil cochleae, including SGN sub-types, and to validate (opto-)genetic therapies preclinically (see screenshot). CochleaNet is also applicable to lower-resolution data from commercial systems.

Cochleae were cleared, stained and imaged with a high-resolution light-sheet microscope (recently published: doi.org/10.1038/s415...). After preprocessing,we segment and analyze the data with CochleaNet, using the three dedicated networks trained on newly annotated data.

Rendering of a full cochlea (left) with three stains (PV, VGlut3, CTBP2) shown in three different colors (red, blue, cyan). The whole cochlea is a spiral shaped structure, with spiral ganglion neurons (SGNs) in the inner helix, labeled by PV and inner hair cells (IHCs) in the outer helix, labeled by Vglur3. The figure also shows zoom ins. The right hand side shows segmentation results for SGNs, IHCs (represented by colored masks) and synapse detections (represented by colored dots).

Preprint alert! CochleaNet, our framework for analyzing light-sheet data of the cochlea. It consists of three networks to segment spiral ganglion neurons, inner hair cells, and to detect synapses. See rendering of a full cochlea in the image, find the preprint at doi.org/10.1101/2025....

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue - Nature Biotechnology A light-sheet microscope built from off-the-shelf components enables high-resolution clear tissue imaging.

🎉 I am very glad to share that our paper on the rapid isotropic light-sheet microscope has just been published in Nature Biotechnology @natbiotech.nature.com.

🔗 Read the full article:
www.nature.com/articles/s41...

Happy to see our paper “Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue” in @natbiotech.nature.com – with Tobias Moser’s lab from @unimedizin-goe.bsky.social and @janwenzel.bsky.social
www.nature.com/articles/s41...

#microscopy #lightsheet

🎓 We're hiring two PhD students in #MachineLearning for my new group at the Hertie Institute for AI in Brain Health, University of Tübingen!

Work on unsupervised learning, #DeepLearning, and #Neuroscience in a vibrant research environment.

👇 Details below

📢 Open 4-year PhD Position in Deep Learning for Bioimage Analysis! | CVPD Research group The Computer Vision and Pattern Discovery (CVPD) group at the University of the Basque Country (UPV/EHU) is offering a fully funded 4-year PhD position within the recently awarded project TOSBI: Towar...

📣 We’re hiring, please RT! Fully funded 4-year PhD position in our CVPD group at @informatikaehu.bsky.social!

Research at the intersection of AI, deep learning & bioimage analysis. 🧠🔬

📅 Applications open Oct 6 (deadline: ~Oct 27)
📍 San Sebastian, Spain.
👉 cvpd.github.io/post/2025-09...

Hope my counter meme convinces you ;)

😂😅

Once again, I beg you to understand that SINGLE-CHANNEL FLUORESCENCE MICROSCOPY IMAGES DON'T HAVE A COLOR!