Adrian Wanner

Recurrent connectivity supports carbon dioxide sensitivity in Aedes aegypti mosquitoes The mosquito Aedes aegypti′s human host-seeking behavior depends on the integration of multiple sensory cues. One of these cues, carbon dioxide (CO2), gates odorant and heat pathways and activates hos...

New preprint from @darbly.bsky.social‬ @briandepasquale.bsky.social‬ and my labs! If you love (or hate) mosquitoes, have a look:

doi.org/10.1101/2025...

We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟

The first full central nervous system connectome dataset of an adult fly, with the most comprehensive annotation of sensory and motor neurons to date.

A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.

Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...

Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...

Fantastic to see this collaborative work with Hopi Hoekstra out in Nature (tinyurl.com/3at3zvby). Lead by @felixbaier.bsky.social and @katjareinhard.bsky.social. Not possible without @bramnuttin.bsky.social , Chen Liu and @arnausd.bsky.social.

Excited to see where this work leads.

Connectomic reconstruction from hippocampal CA3 reveals spatially graded mossy fiber inputs and selective feedforward inhibition to pyramidal cells The mossy fiber (MF) connections to pyramidal cells in hippocampal CA3 are hypothesized to participate in pattern separation and memory encoding, yet no large–scale neuronal wiring diagram exists for ...

Excited to share a connectomics dataset of hippocampus CA3.
Explore the dataset: pyr.ai
Paper introducing the dataset and some of our discoveries: www.biorxiv.org/content/10.1...

Kedar Narayan (right) holds the Alan Agar Award, presented by Paul Verkade (left), who is holding Kedar's certificate. They are both smiling, standing next to a lectern inside a lecture hall.

Huge congratulations to Kedar Narayan who received the RMS Alan Agar Award for #ElectronMicroscopy from Paul Verkade this afternoon at #mmc2025

👏👏👏🔬🙌🥇

@rmsearlycareer.bsky.social @yorkbioimaging.bsky.social

Congratulations Aaron, very well deserved!

Proud to share our latest paper. doi.org/10.1016/j.cr...

Through the dedication of @glynnca.bsky.social and @cryingem.bsky.social we report a thorough method to image molecular organisation within hippocampus tissue.

Structural biology in tissue is well and truly here!

@rosfrankinst.bsky.social

If you want to learn the latest developments in volumeEM from the experts, with hands-on experience on our instruments @embl.org, this course is for you! 🔬

Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...

Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team ‪@yuxinzhang.bsky.social‬, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.

#preprint:

We mapped the structure and function of olfactory bulb circuits with in vivo 2-photon microscopy and synchrotron #Xray holographic nanotomography.

doi.org/10.1101/2025...

@yuxinzhang.bsky.social @andreas-t-schaefer.bsky.social @apacureanu.bsky.social
@crick.ac.uk @esrf.fr

I am honored and excited to announce that I will be starting as group leader at @dandrite.bsky.social and associate professor at @au.dk in August 2025. I look forward very much to joining my future colleagues in Aarhus in doing excellent Neuroscience, with many scientific puzzles ahead to solve!

I am very happy and thankful for having been part of this amazing journey. Enjoy exploring this incredibly rich dataset!

To stop intimidation, Eisgruber needs your help When targeting one institution is a bald attempt to divide and conquer, as is the case with Columbia, it is essential for a coalition or group of institutions and individuals to stand up together.&nbs...

Here at Princeton, we’re amplifying our university president’s leadership. It’s time for everyone - faculty, students, staff - to speak out.

tl;dr: rights can’t be blackmailed.

From me and science colleagues:
www.dailyprincetonian.com/article/2025...

Synaptic architecture of a memory engram in the mouse hippocampus Memory engrams are formed through experience-dependent plasticity of neural circuits, but their detailed architectures remain unresolved. Using three-dimensional electron microscopy, we performed nano...

Synaptic architecture of a memory engram in the mouse hippocampus
www.science.org/doi/10.1126/...

Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish Accumulating information is a critical component of most circuit computations in the brain across species, yet its precise implementation at the synaptic level remains poorly understood. Dissecting su...

We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)

GrimACE: Automated, multimodal cage-side assessment of pain and well-being in mice Pain and welfare monitoring is essential for ethical animal testing, but current cage-side assessments are qualitative and subjective. Here we present the GrimACE, the first fully standardised and aut...

How much analgesia is needed to manage pain levels in mice after brain surgeries?

A single dose of meloxicam seems to be enough. Even the addition of opioids cannot provide a clear benefit. (in line with recent work from others, see cites in our preprint): www.biorxiv.org/content/10.1...

Together with cSAXS, the Coherent X-ray Scattering Group at PSI, we are looking for a
Postdoctoral Fellow on High-Throughput X-ray Ptychographic Imaging of 🧠:
psi.ch/en/hr/job-op...
+ work at 4th gen synchrotron
+ interdisciplinary team science
+ Swiss salary and benefits

Explainer: Why US health funding cuts are rattling Swiss science The Trump administration has upended funding by the National Institutes of Health. What does it mean for biomedical research in Switzerland?

This excellent article by Jessica Plüss explains how the on-going attacks on NIH affect biomedical research and science well beyond the US: www.swissinfo.ch/eng/science/...

The revised version of our #Platynereis #connectome paper is now out:

https://elifesciences.org/reviewed-preprints/97964

Cell-type-level annotation of the whole organisms, including synaptic and desmosomal connectomes. Can be explored with CATMAID here […]

[Original post on biologists.social]

fantastic work!

X-ray nanotomography can be your new friend for neuronal imaging. In our new #preprint (tinyurl.com/nanoXneuro) we present advances that push the spatial resolution limit for X-ray holographic nanotomography (XNH). We can now resolve synapses. 🧵

This summer course is going to be awesome! Please repost and tell your students/postdocs/everyone to apply. We have lots of excellent faculty as well as lectures on #connectome modeling by yours truly and Jonathan Pillow.

Hive mind: Has anyone seen myelinated synapses before? Or what do you think this is?

i will be enthusiastically hosting connectomics luminary @darbly.bsky.social for an @uw-nbio.bsky.social seminar tomorrow. come join us if you can!

An illustration of two plates of cells, with a slight difference in the size of one of the organelles.

Can you spot the difference between the cells on the left and right?

Read on for the solution (and a preprint announcement)… 👇

1/6

Last few days to apply for this position. The LMB, is a wonderful place to grow a group with amazing, collaborative colleagues, core funding and a rich intellectual environment in Cambridge.

Our lab is looking for a postdoc interested in the development, plasticity, and control of cortical circuits (bhariokelab.com).

Please send CV and some research ideas of interest to you. We're flexible & open to new ideas in the lab's general vein!

Please repost! More details at shorturl.at/wLvZw.