Similar to some other suggestions, but Dowtherm A should work and you can find a few refs for its use in hi temp reactions

18.11.2025 19:43 — 👍 1    🔁 0    💬 1    📌 0

This really has the same feel as Niepce's window

16.11.2025 15:30 — 👍 0    🔁 0    💬 0    📌 0

You could do amine + CDI then benzyl alcohol (or alcohol first) if you are in a pinch. Shows up a fair amount for substituted benzyl variants

02.10.2025 13:17 — 👍 3    🔁 0    💬 1    📌 0

Here are some of mine after just one year. So much paler! But kind of ethereal

22.08.2025 01:19 — 👍 0    🔁 0    💬 1    📌 0

It's these failures to do basic governance that make me extremely worried that we are not going to weather and recover from this administration

28.06.2025 16:00 — 👍 1    🔁 0    💬 0    📌 0

5!

21.06.2025 19:09 — 👍 0    🔁 0    💬 1    📌 0

Your axis should be Millions not Billions (implies spending is $117 trillion). It would also be helpful if the years were indicated with the months

03.06.2025 20:43 — 👍 1    🔁 0    💬 0    📌 0

Who wants API salt extraction? 🙋‍♂️ Who wants to live next to API salt extraction? 🙅‍♂️

27.05.2025 20:59 — 👍 1    🔁 0    💬 0    📌 0

I find these papers somewhat interesting but mostly baffling (on top of the questionable description of synthesis). Are these numbers high? Compared to what? Should we aim to have a 100-mile pharmacopoeia?

27.05.2025 20:57 — 👍 1    🔁 0    💬 2    📌 0

Are you asking about the use of prophetic?

19.05.2025 21:56 — 👍 1    🔁 0    💬 0    📌 0

Demonstration on Pilot-Plant Scale of the Utility of 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) as a Catalyst in the Efficient Amidation of an Unactivated Methyl Ester The utility of 1,5,7-triazabicyclo[4.4.0]dec-5-ene as a reagent to facilitate efficient amide formation by reaction of an amine with an unactivated ester was demonstrated on pilot-plant scale as a key...

Alternatively, another personal fav, have you looked at TBD-mediated ester functionalization? e.g. doi.org/10.1021/op30...

08.04.2025 21:39 — 👍 2    🔁 0    💬 2    📌 0

A nice little reaction idea, I've used it on polycarboxylic acids. It can benefit from the standard cat. DMF as well

08.04.2025 21:23 — 👍 2    🔁 0    💬 1    📌 0

I would kindly suggest a Sankey - designed to show flows - is not the appropriate way to represent this data.

10.03.2025 11:28 — 👍 0    🔁 0    💬 1    📌 0