Hung Lo 羅鴻

𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻 𝗮𝗿𝗲𝗮𝘀 𝗿𝗲𝗹𝗮𝘁𝗲𝗱 𝘁𝗼 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻?
"High-resolution activity maps of PFC did NOT align with cytoarchitecturally defined subregions."
Key tenet in neuroscience is that cytoarchitectonic boundaries correspond to functional ones.
NB: study in the mouse
#neuroskyence
doi.org/10.1038/s415...

Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...

⚠️ New paper alert and what a way to end 2025! 🎉
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.

Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8

Posters printed (5x), talks made (2x), symposia chairing ironed out (2x), preprint posted (1x), whole lab on board (7x): 𝐁𝐢𝐥𝐛𝐚𝐨, 𝐡𝐞𝐫𝐞 𝐰𝐞 𝐜𝐨𝐦𝐞! #ECRO2025
🇪🇸🧠👃
ecro2025.com

@chloeg-neuro.bsky.social @harinw.bsky.social @connordoyle.bsky.social @ailiemcwhinnie.bsky.social @neurosana.bsky.social

Feeding-induced olfactory cortex suppression reduces satiation Binge feeding commonly leads to overeating. Experiencing flavor during food consumption contributes to satiation. Still, the interactions between flav…

🧠🔄 #NeuroThursday

Loops paper! 💡
@hunglo.bsky.social, Friedrich Johenning & team show that during binge feeding, OT GABA neurons silence piriform cortex → flavors fade, fullness lags and eating continues!

Who knew smell circuits could fuel overeating? 🐭🧋

🔗 www.sciencedirect.com/science/arti...

Thanks for sharing our work ☺️😁🧋

Feeding-induced olfactory cortex suppression reduces satiation Lo et al. show that binge feeding suppresses piriform (olfactory) cortex activity, reducing the brain’s representation of food flavor. This suppression is driven by the olfactory tubercle and promotes...

New in Neuron: “Feeding-induced olfactory cortex suppression reduces satiation” @CharitéBerlin researchers. This study reveals how the sense of smell controls meal ending & binge eating behavior. Read more: tinyurl.com/227dw782 #Neuroscience #Satiation #BingeEating @hunglo.bsky.social & colleagues

It was a great colab! Thanks so much for your contributions!

Thanks for the highlights! 🙂

🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.

Spoiler alert: Yes, they can!

Read the paper here: bit.ly/43A9tF9
Short 🧵 below

Thank you Jonas, and yes finally 🫠🫠🫠

Thank you!

Thank you soooo much Elisa!!! 😁☺️I hope ppl in the lab enjoy the🧋hahaha

Thanks for kind words Luke! 😄

Finally, some personal updates, since this year I have started my postdoc with @lukesjulson.bsky.social at Albert Einstein College of Medicine in New York, studying prefrontal dynamics in addiction models. Hopefully, soon I'll have something cool to show you all!

Of course, I want to thank all authors that I haven't mentioned yet, thank you all so much!!
Matthew Larkum Benjamin Judkewitz Anke Schoenherr Laura Moreno Velásquez Lukas Faiss Amit Kumar Malinda Tantirigama Aileen Hakus Benjamin Rost Katharina Stumpenhorst Marion Rivalan York Winter!

Special thanks to Walter Cañedo Riedel, Kelsch lab, and @russoel.bsky.social lab for their contribution, where they analyzed the functional connectivity between OT and aPC and showed the recruitment of OT –| aPC circuit, providing a crucial link between these 2 brain regions.

In this version, we identified the missing link in the last version, a circuit mechanism of how the olfactory cortex (aPC) is suppressed during binge feeding. It turns out to be the GABAergic neurons in the olfactory tubercle (OT)! OT neurons project to aPC and are activated during binge feeding!

Thanks again to all the authors, especially my PhD supervisors Friedrich Johenning and Dietmar Schmitz. Thanks to all 3 reviewers, it was a relief to read the reviewers’ comments were all positive and supporting publication!

Paper link:
authors.elsevier.com/sd/article/S...

I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me!

Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰

Great work from @facuumm.bsky.social and @ggirardeau.bsky.social ! Interesting that the cell assemblies activity is so sparse!

Dorso-ventral hippocampus neural assemblies reactivate during sleep following an aversive experience The integration of spatial and emotional components into episodic memory relies on coordinated interactions between hippocampal circuits and emotion-processing regions. While the dorsal hippocampus (d...

Hello folks!
New update on our bioXriv preprint!
With my amazing supervisor @ggirardeau.bsky.social , and the super team @belalima-paiva.bsky.social @azulsilva.bsky.social & Ele

www.biorxiv.org/content/10.1...

🧵1 of 4

A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)

🌟 Exciting News!🌟
I am thrilled to announce that the interdisciplinary symposium Scent and Imagination will take place on the 4th June 2025 in Cambridge (UK)! 🎉

Join us as we dive deep into the complex relationship between olfactory heritage and imagination 🌸💡

Congrats!! Beautiful work!

Perceptual constancy for an odor is acquired through changes in primary sensory neurons Learning-induced changes in primary sensory neurons support concentration-invariant perception of an odor.

We have a fresh new paper!
The PhD project of the talented Mark Conway.

A learning-induced change in the sensitivity of olfactory receptor neurons enables consistent perception of an odor. #olfaction #neuroscience

www.science.org/doi/10.1126/...

a man wearing glasses and a red jacket says allow myself to introduce ALT: a man wearing glasses and a red jacket says allow myself to introduce

I recently created this account and figured I should make an introductory post.

I'm a Ph.D. candidate interested in all things neuroscience, although primarily involved in systems and computational aspects of the brain for the moment. Looking to connect with the neuro folks in here! #neuroscience

Everyone knows that failure is bad. We devote a lot of time to trying to avoid it. But sometimes failure is good.

A brief story: ~11 yrs ago, when my friends were all starting their own labs, I was starting my 2nd postdoc. My 1st postdoc (w/ Gord Fishell at NYU) had ended in disaster when 1/

オプシンの人たちはどこにいるの？

Where are all the opsin people?
Let me know if you want to be listed!

go.bsky.app/DXgqJYs

A moment in time: Dieter Oesterhelt passed away in Münich on this day (November 28) in 2022. He identified the 1st microbial rhodopsin more than 50 years ago, with far-reaching impact that could hardly have been imagined.
laskerfoundation.org/in-memoriam-...