Máté Manczinger's Avatar

Máté Manczinger

@matemanc.bsky.social

Group leader of the Systems Immunology Research Group at HUN-REN Biological Research Centre, Szeged, Hungary

12 Followers  |  31 Following  |  3 Posts  |  Joined: 13.01.2025  |  1.2325

Latest posts by matemanc.bsky.social on Bluesky

C > U mutations generate immunogenic peptides in SARS-CoV-2 - Nature Communications The effect of new viral mutations on T cell responses remains unclear. Here, Balogh et al. show that most new mutations in SARS-CoV-2 are C > U, a bias that leads to an enhanced T cell re...

C > U mutations generate immunogenic peptides in SARS-CoV-2

APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition.

nature.com/articles/s41...

#COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics

01.12.2025 17:48 — 👍 2    🔁 1    💬 0    📌 0
Post image

C > U mutations generate immunogenic peptides in SARS-CoV-2 @natcomms.nature.com @matemanc.bsky.social
@csabapallab.bsky.social
www.nature.com/articles/s41...

19.11.2025 16:23 — 👍 2    🔁 2    💬 1    📌 0
Post image

I C U mutant!

Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19

25.11.2025 07:53 — 👍 0    🔁 1    💬 0    📌 0
Post image

I C U mutant!

Our new paper is out! Our immune system doesn’t just fight viruses – it edits them.
APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition.
nature.com/articles/s41...
#COVID_19

25.11.2025 07:53 — 👍 0    🔁 1    💬 0    📌 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org/doi/10.1073/...

How cancer arises: Genetics releases, plasticity creates, genetics stabilizes

22.09.2025 17:23 — 👍 1    🔁 0    💬 0    📌 0

@matemanc is following 20 prominent accounts