David Usharauli

NIH details options for limiting its payments for open-access publishing fees

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Lithium deficiency and the onset of Alzheimer’s disease - Nature Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the physiological…

Notable observation: A new Nature study links #lithium deficiency to Alzheimer’s.

#science
#alzheimer

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Article: Some AI tools don’t understand biology yet

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HHS slashes funding for mRNA vaccine development

this article provides greater depth and breadth on which programs were affected.

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Government-backed mRNA research comes to an end.

#BARDA
#mRNA
#vaccine

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Just as the Girgvliani case served as a litmus test for Saakashvili’s rule (2004-2012), and failed to pass, Mzia’s case now serves as a litmus test for Georgian Dream

Scientific Journals Can’t Keep Up With Flood of Fake Papers

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American Eagle's Crystal-Clear Defense Of Controversial Sydney Sweeney Ads Signals A Lot Experts say that American Eagle's response to the outrage over its campaign featuring the "Euphoria" actor tells us a lot about the current political climate.

If her "jeans" are blue, then she must be a Na'vi from Pandora.

#Avatar
#NaVi
#BlueJeans
#Pandora
#AmericanEagle
#AEO

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I doubt the validity of this #diabetes cell therapy study. Since the 90s, we’ve known removing class I & II from cells should make them targets for NK cells. CD47 alone shouldn't be enough to hide. Needs much more data and scrutiny.

#Immunology
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This company claimed to ‘de-extinct’ dire wolves. Then the fighting started. Colossal’s bold announcements have drawn criticism from many scientists, but the billion-dollar firm is not backing down.

“I don’t think they de-extincted anything”

If Colossal Bio (@colossal) is eager to do gene editing, why not focus on truly useful work like gene edits to help Tasmanian devils fight cancer? Enough megalomania and George Church’s PR stunts.
#DeExtinction
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The Weekend Tunes

Andrei Banuta - Lasă-mă (să te iubesc) (🇷🇴 Romania)

every gesture by the dark-haired woman syncs beautifully with the rhythm of the song.

#WorldMusic 🌍🎧
#MusicUnites ❤️🎵

www.youtube.com/watch?v=-R3g...

NSF and NIH suspend grants to UCLA

#science

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Genomewide study makes ‘quantum leap’ in understanding #stuttering

#23andMe
#DNA

rhythm processing deficit

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"The Storm Before the Storm" shows Rome’s Republic cracking, not by breaking laws, but by ignoring unwritten norms. Economic inequality, prejudice over citizenship, and unchecked individual ambition overwhelmed a system never built to run an empire.

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The Weekend Tunes

VIVIZ - La La Love Me (🇰🇷 South Korea)

The way she says 'cheoncheonhi… into, into you' is so cute. #VIVIZ never misses with their stage presence.

#KPOP

#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵

www.youtube.com/watch?v=Z63M...

"overcoming these limitations by using generative artificial intelligence (AI) to design high-specificity pMHC-binding “artificial TCRs” for more precise targeting of tumor antigens."

#science
#immunology
#AI
#cancer
#immunotherapy

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You can’t seriously challenge the government in Georgia when 50 thousand tickets just sold to attend a Justin Timberlake concert. Who even listens to him anymore, let alone during a political crisis?

The whipsawing of Windsurf employees has left a bitter taste in Silicon Valley. The whipsawing of Windsurf employees and the unusual cleaving of the company into separate parts have left a bitter taste in Silicon Valley.

'This breaks the Silicon Valley social contract:' The whipsawing of Windsurf employees has left a bitter taste in tech

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It is obvious the Georgian Dream team made some serious miscalculations. The West is determined to put Russia in the same position it was in after the Crimean War in 1856. It will not allow Russia to extend influence beyond its own borders. The only question is how long it will take.

Back then, one patient death was enough to shut down gene therapy research for years. Now, it took three deaths and firm FDA action to stop a company from continuing unfazed.

#biotech
#FDA
#sarepta

www.fiercebiotech.com/biotech/sare...

'Users could “launch a bunch of Comet assistant jobs” and then, as Srinivas puts it, spend their time on other things while the AI works.'

But at that pace, there may not be much 'other work' left for white-collar workers.

#AI

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Allergies seem nearly impossible to avoid — unless you’re Amish

#immunology
#science
#allergy
#microbiota

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China is catching up to the US in brain tech, rivaling firms like Elon Musk’s Neuralink

#science

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Florida’s COVID-19 cases, already higher than winter levels, are still climbing.

#COVID
#COVID19
#COVID19Surge
#COVID19Florida

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"administration of lipid particles loaded with RNA coding for tumour-unspecific antigens"

So much for the painstaking search for tumor-specific #neoantigens. Turns out you can just throw in whatever, or even nothing at all, and it still somehow works.

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The Weekend Tunes

Bessan Ismail - Al Harbein (🇸🇾 Syria/🇦🇪 UAE)

Nice, though it borrows heavily from Al Shami’s hit “Wein”. Fun fact: both singers were born in Syria, bringing authentic Levantine flavor to Arabic pop!

#WorldMusic🌍 🎧
#MusicUnites ❤️🎵

www.youtube.com/watch?v=hDd4...

Novome Biotechnologies’ study shows engineered Bacteroides can engraft and lower oxalate in humans. However, Synlogic, Kaleido, and Evelo have all folded. Will Novome’s approach change the game or fade like previous attempts? 🧫⚖️

#biotech
#microbiota

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The Georgian Dream government seems to ignore that much of Georgia’s current confidence in dealing with the EU and US was built on their financial support. Challenging these partners as equals is premature unless Georgia repays its debts. True sovereignty demands it.

#Georgia

In my view, the question of T helper cell differentiation should be divided into: (A) stochastic phenotype acquisition by naïve T cells via innate signals, and (B) pathological responses from cross-reactive, pre-existing memory T cells.

#immunology

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I think this is the first time I’ve seen a leading immunology journal published in the West display Chinese authors’ names in Chinese characters. Seems like Immunity knows where things are headed.

#science
#china

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