Andrea B

Should More People Be Treated for Hepatitis B? Antiviral treatment for HBV lowers the risk for liver cancer and other complications and can prevent transmission.

Although current guidelines say many people with chronic hepatitis B don't need treatment, a growing number of clinicians & advocates are calling for simplified recommendations and expanded eligibility.
www.hepmag.com/article/peop...

Health officials investigate mystery disease in southwest Congo after 143 deaths Medical experts have been sent to southwestern Congo after a mystery disease killed dozens of people over two weeks, authorities said.

MYSTERY EPIDEMIC IN CONGO—Health officials investigate a new unidentified mystery flu-like disease in southwest Congo after 143 deaths, mostly in kids. The reported symptoms in patients include:
• Fever
• Headache
• Nasal discharge and cough
• Difficulty breathing
• Anemia
apnews.com/article/cong...

This really important!
Brilliant study!
For all organisms studied, the highest risk period of progression from colonization to infection was the first 90 days after colonization detection; however, the authors still observed infection risk up to 2 years after colonization detection #idsky #medsky

Ten years ago Ebola tore through Sierra Leone. Can a vaccine drive stop history repeating itself? Memories of 2014, when the disease ravaged west Africa, are raw, while risk remains high. This week the first ever nationwide prevention programme begins – and doctors hope it will be enough to fend o...

Sierra Leone will this week become the 1st country to launch a nationwide preventive #Ebola vaccination campaign for people at the highest risk. Over 3 weeks, will deliver 20k doses of Merck’s Ervebo vaccine in a drive that will be repeated every 2-3 years. #IDSKY
www.theguardian.com/global-devel...

Dengue This JAMA Insights explores several aspects of dengue virus infection, including epidemiology, diagnosis, and clinical management, following a global resurgence in both endemic and nonendemic regions.

Dengue has resurged globally with larger outbreaks in endemic areas and new cases in nonendemic regions, facilitated by range expansion of vector mosquito populations and climate change, population growth, and urbanization
#idsky #medsky
jamanetwork.com/journals/jam...

Exactly! Evidence is too poor on that matter. Probably research on this new outbreak will shed more light on differences in mortality between clades.

The changing epidemiology of human monkeypox-A potential threat? A systematic review - PubMed Monkeypox, a zoonotic disease caused by an orthopoxvirus, results in a smallpox-like disease in humans. Since monkeypox in humans was initially diagnosed in 1970 in the Democratic Republic of the Cong...

Sure, here it is: pubmed.ncbi.nlm.nih.gov/35148313/

The WHO Director-General, agreeing with the advice of the IHR Emergency Committee, has determined that the upsurge of #mpox continues to constitute a public health emergency of international concern.

🦟 Toujours 85 cas autochtones de #dengue en France hexagonale (tous dans le sud-est), et toujours un foyer non clos.

Quoi qu'il en soit : nouveau record, le précédent était de 66 (il y a 2 ans).

PS : le foyer isolé d'un cas en région parisienne, c'est du chikungunya.

1/2

However looking at demographic data, it was shown that in cladeIb outbreaks children were the most affected. The severity of mpox is much greater in paediatric patients than adults, therefore age alone might be responsible for the differences in mortality.

Yes. Reason why is thought clade IB is more sever is based on some systematic reviews (eg: Burge et al 2022) which measured mortality % in outbreaks caused by different clades. Conclusion is that clade Ib caused more deaths.

🦟 "Autochthonous #dengue #outbreak in Marche Region, Central #Italy, August to October 2024" by Chiara Sacco et al. in @eurosurveillance.bsky.social
www.eurosurveillance.org/content/10.2...