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@phdpetrelli.bsky.social

32 Followers  |  63 Following  |  1 Posts  |  Joined: 13.01.2025  |  1.4138

Latest posts by phdpetrelli.bsky.social on Bluesky

This is a great work indeed!!!

17.05.2025 16:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Postdoctoral Position in Human Metabolism, Mitochondria & Behavior at EPFL - Federation of European Neuroscience Societies

Hiring! Postdoc position in Human Metabolism!
Join us to explore the metabolic underpinnings of human brain & behavior; focusing on anxiety & motivation
Outstanding interdisciplinary environment @epfl-brainmind.bsky.social at EPFL in Lausanne Switzerland
Info here: www.fens.org/careers/job-...

01.04.2025 16:37 โ€” ๐Ÿ‘ 19    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Varicose-projection astrocytes: a reactive phenotype associated with neuropathology Glial cells are fundamental for the pathophysiology of all neurological disorders. Astrocytes, the primary homeostatic cells of the central nervous system (CNS), exhibit species-specific characteristi...

๐ŸšจThe first #preprint of the #FalconeLab is OUT!๐Ÿฅน๐Ÿšจ

We found that varicose-projection astrocytes are not a physiological type of #astrocytes but they are rather associated with neuropathology.

Read more here, feedback is welcome!!

More details๐Ÿ‘‡๐Ÿ‘‡
1/
www.biorxiv.org/content/10.1...

18.03.2025 15:42 โ€” ๐Ÿ‘ 35    ๐Ÿ” 9    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter - Nature Neuroscience White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in cerebellar WM, suggestin...

๐Ÿš€ Think all white matter (WM) astrocytes are the same? Think again! ๐ŸŒŸ Our latest research reveals striking regional differences that challenge existing views on astrocyte diversity and function. ๐Ÿง 

www.nature.com/articles/s41...

24.02.2025 16:06 โ€” ๐Ÿ‘ 33    ๐Ÿ” 10    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Trying my best to focus on some positive science content. We feel so grateful to have our work highlighted on the cover of @naturecellbiology.bsky.social!

This beautiful #astrocyte reconstructed from the raw data images used in the paper. Most of which are never typically seen! rdcu.be/d5ADz

18.02.2025 12:07 โ€” ๐Ÿ‘ 50    ๐Ÿ” 11    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 0
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Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function - Nature Communications Remyelination can restore neural function. Here, the authors characterize the drivers and limits of endogenous remyelination and explore a therapy that rescued remyelination deficits and accelerated n...

New paper out from the lab! Led by @gdfnunes.bsky.social and Lindsay Osso in collaboration with the lab of Dan Denman. Check it out! ๐Ÿ”ฌ ๐Ÿญ ๐Ÿง 

www.nature.com/articles/s41...

18.01.2025 18:41 โ€” ๐Ÿ‘ 60    ๐Ÿ” 26    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - Nature Metabolism Tutas et al. show an unconventional role for autophagy in the regulation of glycolytic flux in cerebellar Purkinje cells by maintaining the levels of the glucose transporter GLUT2.

Check this great paper from the Kononenko lab at @cecad.bsky.social

"Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity"
www.nature.com/articles/s42...

18.01.2025 10:14 โ€” ๐Ÿ‘ 19    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain - Nature Biotechnology Transplantation of glia-enriched organoids into the mouse brain enables the study of astrocyte subtypes.

โญ๏ธ Wang et al.: Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain โญ๏ธ
www.nature.com/articles/s41...

18.01.2025 07:37 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Multimodal transcriptomics reveal neurogenic aging trajectories and age-related regional inflammation in the dentate gyrus - Nature Neuroscience Multimodal transcriptomics unveil the molecular dynamics of neural stem cells and their surrounding niche in the aging mouse hippocampus and provide a resource to understand age-related molecular chan...

Molecular dynamics of neural stem cells (NSCs) and their surrounding niche in the #aging mouse #hippocampus using multimodal transcriptomics ๐Ÿงช๐Ÿง 

www.nature.com/articles/s41...

10.01.2025 16:59 โ€” ๐Ÿ‘ 21    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

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