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Thomas Clavel

@tclavel.bsky.social

Passoniate microbiome research; www.clavel.ukaachen.de

185 Followers  |  160 Following  |  16 Posts  |  Joined: 28.03.2025
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Posts by Thomas Clavel (@tclavel.bsky.social)

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Seeon - Deutsche Gesellschaft für Hygiene und Mikrobiologie Microbiota, Probiotics and Host    Seeon- Save the date 2026 Registration Abstract Template 2026   We are looking forward to meeting you there! Don’t forget your swimwear, sunscreen and running gear ...

Registration for the 18th Annual Seeon Conference on Microbiota, Probiotics and Host is now open! 🎉

We’re looking forward to welcoming you in Seeon!

When: June 24-26
Where: Seeon Monastery, Germany (near Munich)
Program: www.dghm.org/seeon/
Registration: app1.edoobox.com/SPP1656/Seeo...

18.02.2026 08:48 — 👍 6    🔁 5    💬 0    📌 2
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☕ Join our next NFDI4Microbiota Tandem Coffee Talk!
📅 Mon, 23 Feb 2026 | 14:00–15:00 CET
🎙️ Prof. Dr. Bas E. Dutilh & Dr. Noriko Cassman
💬 “Learning phage-host interactions from curated big data” & “VirJenDB: a FAIR (meta)data and analysis platform for viruses”

👉 More info here: tinyurl.com/5y7h6wfh

13.02.2026 08:38 — 👍 3    🔁 1    💬 0    📌 0
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Krebsforscherin: "Prävention ins Zentrum stellen" Ärztin Carolin Schneider forscht mit KI-Experten an der RWTH Aachen zur Krebsprävention. Ziel ist die personalisierte Strategie: "Wir glauben, dass wir gute Modelle entwickeln können, die die Einzel-F...

Prof. Carolin Schneider von der Uniklinik RWTH Aachen forscht mit KI-Fachleuten zur Krebsprävention. Ziel ist die personalisierte Strategie: "Wir glauben, dass wir gute Modelle entwickeln können, die die Einzel-Faktoren berücksichtigen, die jemand mitbringt."

➡️ www1.wdr.de/mediathek/au...

05.02.2026 14:48 — 👍 1    🔁 1    💬 0    📌 0

We’re hiring 2 Postdocs (f/m/d) in Drug–Microbiome–Host Interactions 🦠💊

Focus: how non-antibiotic drugs shape the gut microbiome, drug efficacy & side effects.

#PostdocJobs #Microbiome #AcademicJobs

Full job ad:
lisamaierlab.com/wp-content/u...

22.12.2025 14:08 — 👍 16    🔁 18    💬 0    📌 1
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Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer Background Western diet and associated production of secondary bile acids (BAs) have been linked to the development of sporadic colorectal cancer (CRC). Despite observational studies showing that seco...

Now published 🔥 Feeding your gut microbes with complex carbohydrates can help preventing colorectal cancer by reducing the production of secondary bile acids. Perhaps NiMe diet @jenswalter15.bsky.social? THX team & Sören Ocvirk ⭐ Thx www.sfb.tum.de/1371/microbi.... Article 👉 doi.org/10.1136/gutj...

19.12.2025 07:50 — 👍 3    🔁 1    💬 0    📌 0
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Save the Date! 📅

The NFDI4Microbiota Annual Conference 2026 will take place 15–17 September 2026 and will be a joint event with other biodata-related NFDI consortia. Stay tuned for more details!

#onenfdi #NFDI4Microbiota #rdm #microbiota

16.12.2025 06:53 — 👍 4    🔁 3    💬 0    📌 0
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Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites - Analytical and Bioanalytical Chemistry The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....

📍Our paper is out!📍

Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including short-chain fatty acids, indols, nucleotides, organic acids, and amino acid derivatives.
Check it out!

link.springer.com/article/10.1...

16.12.2025 10:56 — 👍 16    🔁 6    💬 0    📌 1
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Franziska Faber and I are recruiting shared postdocs, PhD students to work on Fusobacterium & new BGCs. www.helmholtz-hiri.de/fileadmin/HI...

12.12.2025 15:43 — 👍 11    🔁 19    💬 1    📌 0

New paper from the lab!
Led by Patrick Müller: we show that non-antibiotic compounds — but not macrolide antibiotics — can induce an efflux pump that protects Bacteroidaceae from macrolides.
A neat twist on drug–microbe interactions... www.tandfonline.com/doi/full/10....

09.12.2025 10:33 — 👍 19    🔁 11    💬 0    📌 1
📣 Open position: We are looking for a new #ScientificLead for the #SILVA database 🧬🖥️

📣 Open position: We are looking for a new #ScientificLead for the #SILVA database 🧬🖥️

📣 Open position: We are looking for a new #ScientificLead for the #SILVA database 🧬🖥️

You will be responsible for guiding the development of this important resource and for curating the SILVA taxonomy🌳and more!

👉 www.dsmz.de/dsmz/career/...

Read and share ‼️

#sciencejobs 🦠🧪 #career #taxonomy

22.11.2025 15:36 — 👍 13    🔁 18    💬 0    📌 0
Fast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu) Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies...

Want to delineate genera? We have been optimising POCP, and propose POCPu, which stops the 'double counting' of proteins in POCP by only allowing unique matches. We also speed up, and benchmarked, the analysis using DIAMOND; peerj.com/articles/202... (now implemented in Protologger)

14.11.2025 09:31 — 👍 2    🔁 2    💬 0    📌 0
Fast and robust estimate of bacterial genus novelty using the percentage of conserved proteins with unique matches (POCPu) Accurate taxonomic assignment of bacterial genomes is essential for identifying novel taxa and for stable classification to enable robust comparison between studies. Bacterial genus delineation relies...

Great work from our FAIR science master Charlie (www.linkedin.com/in/charliepa...) to delineate bacterial genera: peerj.com/articles/202.... We hope this will help many. The POCPu calculation is now implemented in protologger.bi.denbi.de by @tcahitch.bsky.social. Thanks for the hard work you 2 ⭐⭐

14.11.2025 14:08 — 👍 2    🔁 1    💬 0    📌 0
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Need a hand with your #Nextflow or #nfcore pipeline?
Join our weekly drop-in session — every Friday 10–11 CET with Daniel Straub (Uni Tübingen).
Ask questions, get tips, and connect with the community!
📍 Zoom: tinyurl.com/mwz84xvb
#Bioinformatics #OpenScience #NFDI4Microbiota

05.11.2025 08:18 — 👍 1    🔁 1    💬 0    📌 0

A place to be 👇 Highly recommended ⭐⭐⭐⭐⭐

30.10.2025 16:37 — 👍 1    🔁 0    💬 0    📌 0
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Botnar Institute of Immune Engineering - BIIE (Zürich): Postdoctoral Researcher (100%): Mechanisms of action of mucosal adjuvants Botnar Institute of Immune Engineering - BIIE has a job opening for Postdoctoral Researcher (100%): Mechanisms of action of mucosal adjuvants in Zürich (published: 30.10.2025). Apply now or check the ...

We have an opening for a postdoctoral researcher in my group at the Botnar Institute for Immune Engineering in Basel, Switzerland. The project is aimed at developing novel mucosal adjuvants for application in oral vaccines. Deadline to apply 16.11.25! Please re-post 🔬🧬

join.com/companies/im...

30.10.2025 13:03 — 👍 6    🔁 4    💬 0    📌 2
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☕ Grab your coffee and join our next NFDI4Microbiota Coffee Talk! 📅 Mon, 27 Oct 2025 | 14:30–15:30 CET
🎙️ Daniel Straub (QBiC Tübingen)
💬 “Meta-omics Analysis at a Bioinformatics Core Facility – As FAIR as Possible”. More info here: nfdi4microbiota.de/c...

24.10.2025 16:08 — 👍 5    🔁 3    💬 0    📌 0

A toolkit for transposon libraries and functional genomics in intestinal Bacteroidales https://www.biorxiv.org/content/10.1101/2025.10.10.681549v1

11.10.2025 03:16 — 👍 9    🔁 7    💬 0    📌 2
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Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....

📍Paper alert 📍

Our new preprint is available on: chemrxiv.org/engage/chemr...

Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including SCFA, indols, organic acids, and amino acid derivatives.

24.09.2025 10:43 — 👍 20    🔁 7    💬 0    📌 0
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Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies Abstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom

The main work from my time in Aachen is now out 🎉 if you have wanted to make a SynCom that captures the functional-landscape of microbiota, MiMiC2 makes that possible based on metagenomic data! 1/7 doi.org/10.1093/isme...

24.09.2025 13:22 — 👍 16    🔁 11    💬 1    📌 0
Validate User

Interested in the design of defined microbial communities for fundamental research and applications? Hope this work & tool will help you 👇 As always @tcahitch.bsky.social has been a driving factor ⭐⭐⭐! github.com/ClavelLab/Mi...; academic.oup.com/ismej/advanc...

18.09.2025 12:11 — 👍 8    🔁 5    💬 1    📌 0

Come and be my colleague at the Dunn School! It‘s a brilliant place to work and exciting to be building up our immunology team. Do apply. Do pass on the news 💉🧬🦠🔬🧫

10.09.2025 20:11 — 👍 8    🔁 11    💬 0    📌 0
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We’re heading to Jena for two exciting events!
📍 DGHM 2025 – 24 Sept
Workshop: Data madness: Navigating Host Microbiomes
Featuring VirJenDB – virus sequence discovery & analysis
Details 👉 programme.conventus....

11.09.2025 07:55 — 👍 7    🔁 4    💬 1    📌 1
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Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project An analysis of TCGA whole-genome sequencing samples yields a comprehensive resource for investigating the role of microbes in cancer.

We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge www.science.org/doi/10.1126/... and the accompanying news piece, www.science.org/content/arti...

03.09.2025 20:45 — 👍 19    🔁 7    💬 0    📌 0

Interested in exploring prophages in your (meta)genomes, but don't know how and where to start? We've put together a beginners guide to exploring viral diversity in prokaryotes @marievasse.bsky.social
@sebwielgoss.bsky.social
@oxunipress.bsky.social

04.09.2025 15:15 — 👍 24    🔁 12    💬 0    📌 0
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Planning, sequencing… and now analysis. 📊
☕ Coffee Talk: Getting Your Microbiome Research on the Road – Managing Your Data using Qiita
🗓️ Aug 25, 2025 | 14:30 CEST
👉 More info: tinyurl.com/2m9jpf2p
👉 Workshop (Oct 22–24, Gießen): tinyurl.com/4w8mczh7

19.08.2025 09:56 — 👍 3    🔁 3    💬 1    📌 0

🌍 Open Call! RWTH Aachen University invites postdocs from outside the EU to apply for the “Port to Europe” Fellowship (24 months funding, all disciplines). Start your research journey at one of Europe’s top universities! 🚀 Deadline: Oct 5, 2025. 👉https://rwth-aachen.de/go/id/botjje/lidx/1

18.08.2025 18:18 — 👍 1    🔁 6    💬 0    📌 1
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Do you have experience in metabolomics/lipidomics/exposomics?

Check out the EMBL ARISE2 Fellowship Programme!
🔗 www.embl.org/training/ari...

📩 Contact: Juan Antonio Vizcaíno — Team Leader, EMBL-EBI
🔗 www.ebi.ac.uk/people/perso...

📌 Applications close soon!
📆 30/09/2025
More info below👇

01.08.2025 14:04 — 👍 0    🔁 2    💬 0    📌 0
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Group Leader – Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

30.07.2025 15:14 — 👍 72    🔁 78    💬 1    📌 1
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Non-antibiotics disrupt colonization resistance against enteropathogens Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...

Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG

16.07.2025 21:20 — 👍 88    🔁 42    💬 2    📌 3

A pure « délice » to have followed this story unfolding under our eyes.
Congrats @ameliejoly.bsky.social brilliantly followed-up by @lucasrebiffe.bsky.social.
@filipedevadder.bsky.social and I were/are so lucky to work with gifted Ph’D candidates like you!

12.07.2025 15:37 — 👍 3    🔁 1    💬 1    📌 0