Zhaolong Adrian Li

Figure

Restricted normalized isotropic values were associated with age and bidirectional links to weight gain. ja.ma/4lLyILB

Data Sharing - ABCD Study

FYI, if you want to be prepared to apply for the next ABCD Study data release, prepare for these new NIST security requirements 🧠: @ohbmofficial.bsky.social abcdstudy.org/scientists/d...

Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eatin...

New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...

New blog post in the making. I guess some topics (unfortunately?) never get old.

Are you doing EMA research and wonder how to go about it? In recent work we've adressed some open questions and challenges, here is a brief summary of papers and materials.

🧵 #PsychSciSky 🧪 #StatsSky

Towards accredited clinical training in brain stimulation: Proceedings from the brain stimulation subspecialty summits The rapid development and clinical use of brain stimulation has renewed debates about whether to define and accredit a pathway for clinical subspecial…

If a doctor is going to stimulate your brain, should they receive special training first? Congrats @shansiddiqi.bsky.social @braincircuits.bsky.social on leading this effort to make brain stimulation a certified clinical subspecialty: www.sciencedirect.com/science/arti...

New paper in Imaging Neuroscience by Maria Hakonen, Jyrki Ahveninen, et al:

Individual connectivity-based parcellations reflect functional properties of human auditory cortex

doi.org/10.1162/imag...

Cell ‘fingerprints’ identify distinct cortical networks These networks align with different assemblages of cells, a finding that could reveal how cellular diversity influences brain function, according to a new study.

We are thrilled that Holmes lab recent paper by Xihan Zhang et al. has been featured on the cover of The Transmitter!@thetransmitter.bsky.social!
Check out the paper here: tinyurl.com/cellnetworks

And the article 🖇️ 🧬
www.thetransmitter.org/neuroanatomy...

Last week to grab a virtual registration for Whistler Brain starting this weekend - get the link for the talks!
web.cvent.com/event/34b0c2...

Careful now, I had a WashU psych class with the syllabus in comic sans…

Ikr I saw the same for a paper published in 2002!!

Also, unrelated, has anyone been spammed by “comments” to ResearchGate papers?? Can’t seem to turn comments off and very worried it will turn into Twitter/X

As if there wasn’t enough to worry about…

It turns out the Salience (SAL) and Parietal Memory Networks (PMN) are the same thing!

😩😩😩

🧵

Matching, missing data, a quasi-experiment, and causal inference--Oh my! | A. Solomon Kurz I'm finally dipping my does into causal inference for quasi-experiments, and my first use case has missing data. In this post we practice propensity score matching with multiply-imputed data sets, and...

New blog up: solomonkurz.netlify.app/blog/2025-02...

This time I dip my toes into causal inference for quasi-experiments using matching methods, and my use case has missing data complications. Many thanks to @dingdingpeng.the100.ci and
@noahgreifer.bsky.social
for their peer review! #RStats

It feels weird to be promoting myself in the midst of *gestures wildly*, but I've been working on this project for a while and I'm super proud of it! One possible answer to the question of "What to do about the low reliability of task fMRI?" a 🧵 #neuroskyence #fMRI #Neuroimaging (1/11):

𝗜𝗻𝘀𝘂𝗹𝗮 𝗰𝗶𝗿𝗰𝘂𝗶𝘁 𝗶𝗻𝘃𝗼𝗹𝘃𝗲𝗱 𝗶𝗻 𝗶𝗺𝗺𝘂𝗻𝗲 𝗵𝗼𝗺𝗲𝗼𝘀𝘁𝗮𝘀𝗶𝘀
The insula is the place of magic in the brain... (one of them at least)
www.nature.com/articles/s41...
(h/t @jrbneuropsiq.bsky.social )
#neuroskyence

The brain’s action-mode network - Nature Reviews Neuroscience The brain enters an action-mode of function during goal-directed behaviour. In this Perspective, Dosenbach, Raiche and Gordon describe “action-mode” as an informative functional label that reduce...

The brain’s action-mode network — a Perspective by Nico U. F. Dosenbach, Marcus E. Raichle & Evan M. Gordon
@ndosenbach.bsky.social @gordonneuro.bsky.social
www.nature.com/articles/s41...

The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow - Nature Neuroscience The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to input from the sensory cortex and a core relatively insulated from environmental input, and it uniquely balances its output across sensory hierarchies.

Out in @natureneuro.bsky.social today 🥂

Cytoarchitecture, wiring and signal flow of the human default mode network

Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations

Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏

Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...

The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵

JCPP Advances | ACAMH Child Development Journal | Wiley Online Library Machine learning based prediction of cognitive resilience among low income youth.

In our 🚨 NEW PAPER 🚨 "Beyond the income-achievement gap: The role of individual, family, and environmental factors in cognitive resilience among low-income youth", we used machine learning to characterise predictors of cognitive resilience.

acamh.onlinelibrary.wiley.com/doi/full/10....

Wait you don’t have 120% workload?? Waaaat

Longitudinal Trajectories of Cognition and Neural Metrics as Predictors of Persistent Distressing Psychotic-Like Experiences Across Middle Childhood and Early Adolescence | bioRxiv www.biorxiv.org/content/10.1...

Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠

Formation of long-term memory without short-term memory revealed by CaMKII inhibition - Nature Neuroscience Inhibiting CaMKII impairs short-term memory (STM) in mice during an avoidance task but does not affect long-term memory (LTM). This suggests that STM and LTM are processed differently, with CaMKII cri...

Another fascinating study from the Yasuda lab:
www.nature.com/articles/s41...
CaMKII inhibition immediately after training impairs memory transiently. Memory recovers a day later!

We often mind-wander about our past, present, & future. What happens when our minds drift towards our bodies? In a new fMRI study (n ~ 500), @leahbanellis.bsky.social + team discovers unique neural, affective, & physiological correlates of "body-wandering" at rest. www.biorxiv.org/content/10.1...

A VERY PRETTY brain connectome diagram.

Took me two solid days of data munging and coding but I finally figured out how to create these gorgeous connectome/circle plot diagrams. This is the Yeo 7-network brain parcellation, with major connections in a group of healthy adults.

Another fun, low coding threshold, resource: partR2 package is useful for being able to flexibly pull R2 under various specifications (e.g., marginal, conditional, partial, inclusive, etc.) in generalized linear mixed models.

#Rstats #Statistics #AcademicSky

cran.r-project.org/web/packages...

Fascinating work! I love it!! I wonder if stress could be a factor here? I remember as a kid I hated the first few wks of school after summer, bc I was sad saying bye to friends and grandparents, anxious with new materials, and worried I had lost my study skills. Is there a way to measure this?