Our very own newly minted PhD @jasmineleighb.bsky.social is the @victorchang.edu.au Star Scientist for November. Best of all, she's currently looking for postdoc opportunities for 2026. Hit her up if you think she might be a good fit for your lab. #teammassspec #obesity #nad 👩🔬🧪
05.11.2025 23:25 — 👍 10 🔁 4 💬 0 📌 0
Our new study, published in @frontiersmedia.bsky.social in collaboration with @charlesuni.cuni.cz, reveals crucial insights into blood cells formation in newborns. Right after birth, the liver reduces the production of erythrocytes much faster than leukocytes!😮
👉doi:10.3389/fped.2025.1572836
#liver
26.08.2025 18:37 — 👍 3 🔁 1 💬 0 📌 0
🎓 Join us as a Junior Research Group Leader!
🔗 Details here: lnkd.in/eGUP5DxW
👇 Please share with potential candidates!
24.06.2025 10:28 — 👍 2 🔁 1 💬 0 📌 0
🧪 Mezi 10 nejúspěšnějšími českými osobnostmi a projekty, které letos v tradiční anketě Inovátoři roku vybíraly #hospodarskénoviny, uspěl i Dr. Miloslav Polášek, vedoucí skupiny Koordinační chemie z @iocbprague.bsky.social.
10.04.2025 13:05 — 👍 2 🔁 1 💬 1 📌 0
We are excited to share our recently published interdisciplinary paper that bridges organic chemistry, analytical chemistry, bone physiology, and bioinformatics to explore the lipogenic mechanisms of thiazolidinediones (TZDs) on osteogenesis and adipogenesis. Our research reveals that the new generation of TZDs enhances peripheral insulin sensitivity while preserving bone structure.
The accompanying image illustrates the divergent fates of bone marrow mesenchymal stem cells when exposed to TZDs, leading to either fragile or healthy bone. Our study demonstrates that inhibition or silencing of the mitochondrial pyruvate carrier plays a crucial role in this process, as evidenced by 13C metabolic flux analysis.
Key takeaways from our research:
1. Subcellular fluxomics: We developed a novel approach to infer metabolic fluxes in mitochondria and cytosol under physiological conditions. This method combines bioorthogonal click chemistry, LC-MS/MS, and 13C-labeled tracers, providing unprecedented insights into compartment-specific metabolism.
2. Bioorthogonal mitochondrial probes: We designed innovative probes targeting mitochondrial carbonyl-containing metabolites using a modified TPP+ moiety. This advancement allows for precise tracking of mitochondrial-specific metabolic processes.
3. Complex lipid metabolic flux analysis: By employing isotope labeling techniques, we conducted simultaneous analysis of multiple lipid pathways. This comprehensive approach yielded quantitative insights into lipid flux distributions, enhancing our understanding of lipid metabolism dynamics.
📜 Brejchova K. et al. Uncovering mechanisms of thiazolidinediones on osteogenesis and adipogenesis using spatial fluxomics. Metabolism. 2025, Feb 11:166:156157. doi: doi.org/10.1016/j.me...
#Metabolomics #Lipidomics
18.02.2025 09:47 — 👍 1 🔁 0 💬 0 📌 0
Chiral SFC-MS for FAHFA enantiomer separation.
• First report of chiral SFC separation of fatty acid esters of hydroxy fatty acids.
• Offline 2D approach with LC fractionation of regioisomers and chiral SFC-MS of fractions.
• Characterization of the enantiomeric composition of biological samples.
📜 Kozlov O., Lisa M., Riecan M., Kuda O. Chiral supercritical fluid chromatography-mass spectrometry with liquid chromatography fractionation for the characterization of enantiomeric composition of fatty acid esters of hydroxy fatty acids. Anal. Chim. Acta, Volume 1345, 2025 doi.org/10.1016/j.ac...
03.02.2025 07:47 — 👍 0 🔁 0 💬 0 📌 0
💡 Opening #Bioinformatician (m/f) #postdoc position focused on mass spectrometry, #metabolomics, #lipidomics, and #fluxomics.
Read more: fgu.cas.cz/wp-content/u...
07.01.2025 09:22 — 👍 2 🔁 1 💬 0 📌 0
Project team leader at Helmholtz Munich
Our research helps medicine. We are a leading Czech biomedical research center studying normal and pathological physiology, focusing on metabolism, brain, and heart to advance prevention, diagnosis, and treatment of major non-infectious diseases.
Scientist interested in lipids, membranes and cell biology working at Jožef Stefan Institute in Ljubljana, Slovenia; Assoc. Prof. at Jozef Stefan Postgraduate School; Lipid droplets, membranes, cell biology, ferroptosis, autophagy, cancer.
Engineer at Inserm I2MC,
Head of MetaToul, expert in
Metabolomic and specially in Lipidomic, secretary of Réseau Francophone de Fluxomique et Metabolomique
The laboratory at the University Hospital of Regensburg focuses on the development of novel methods to quantify lipid species and trace their metabolism using stable isotopes.
https://lipidomics-regensburg.de
https://metabolomics.ucdavis.edu/
#metabolomics #bioinformatics #massspec #biochemistry #lipidomics
Group Leader at the Institute of Organic Chemistry and Biochemistry (IOCB Prague @iocbprague.bsky.social). Plant biochemistry, metabolomics, genomics, bioML, etc. https://www.pluskal-lab.org
LC-MS and fancy lipids
📍Dresden, Germany
Structural Biologist, Biocurator @lipidmaps
Cardiff Uni (tweets do not represent...etc)
Organist, historic aviation enthusiast and wombler
Not a pilot
Food scientist, Professor @ University of Hohenheim, Germany. Formerly Erlangen & Bristol. Lipids and lipid oxidation in food and archaeology, analytical chemistry. ORCID: 0000-0002-4311-7351
Non-work interests include food, birds and athletics. And memes!
Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
https://www.nature.com/natmetab/
Explore groundbreaking news and research from PNAS, one of the world's most-cited scientific journals. Discover its sibling journal, @pnasnexus.org, both official journals of the National Academy of Sciences. Visit www.pnas.org for more info.
The JCI is a premiere venue for discoveries in basic and clinical biomedical science that will advance the practice of medicine. Est. 1924
Research group at the @idisba.bsky.social using #MSimaging to study the beautiful #lipid landscapes in tissues focused on cancer microenvironments. Posts by Gwendolyn Barceló-Coblijn
Data Enthusiast and Scientist
Always learning, always curious. Passionate about letting data tell the story and driving insights that make a difference. Exploring the intersection of public and individual health, biology and bioinformatics.
Metabolomics, exposomics, systems medicine, health.
Publications: https://scholar.google.com/citations?user=9044ZHIAAAAJ&hl=en
Professor of Medicine (Systems medicine) at Örebro University 🇸🇪 & Professor of Biochemistry (Metabolomics) at Turku University 🇫🇮.
Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, and neurobiology research. Published by Rockefeller University Press @rupress.org
🌐 rupress.org/jem
