Tim Weber's Avatar

Tim Weber

@timweber.bsky.social

Image scientist and biomedical engineer at MIT.

70 Followers  |  30 Following  |  12 Posts  |  Joined: 13.09.2023  |  1.4888

Latest posts by timweber.bsky.social on Bluesky


Preview
Dirigo: a future Python alternative to Scanimage? Over the last 20 years, many microscopes that are capable of resonant scanning two-photon microscopy have converged on using ScanImage, a powerful software package with many strengths but also two โ€ฆ

Thankful for this blog piece by @ptrrupprecht.bsky.social on the Dirigo project. Glad you liked the posts!
gcamp6f.com/2025/11/14/d...

21.11.2025 16:24 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Introducing Dirigo #5: Worker Products Iโ€™m writing a series of โ€œbite-sizedโ€ posts about Dirigo, my modular image-acquisition framework for laser-scanning microscopy. Previous posts: [#1 Intro], [#2 Acquisition pipeline], [#3 Hardware inte...

๐Ÿ”ฌ New post in the "Introducing Dirigo" series: Worker Products

Products are the way information is carried from node to node along the acquisition pipeline. TBH I'm pretty proud of this system ๐Ÿ˜€

Introductory post below ๐Ÿ‘‡

04.11.2025 22:37 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Introducing Thorlabs' New VantageProยฎ Resonant Scanner System!

Learn more at https://bit.ly/4qiTwMZ

Ideal for high-speed imaging, this resonant scanner is designed to deflect a laser beam from its original trajectory and continuously scan it over a user-controlled scan angle.

24.10.2025 20:45 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Post image

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

06.10.2025 17:52 โ€” ๐Ÿ‘ 123    ๐Ÿ” 44    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 2
Preview
Introducing Dirigo #4: Unit quantities Iโ€™m writing posts to introduce Dirigo, a flexible image acquisition framework targeting laser scanning applications. Previous posts: #1: Intro, #2: Acquisition pipeline composition, #3: Hardware inter...

๐Ÿ”ฌ ๐Ÿ”ฌ New post in the "Introducing Dirigo" series: Unit quantities

Why units matter (think 100 ยตm vs 100 mm ๐Ÿ˜ฌ), parsing โ€œ400 umโ€/โ€œ8 kHzโ€/"125 MS/s", expressive types, and unit-checked math.

Dirigo achieves this with a light-weight Pint-inspired layer used everywhere units are relevant.

18.09.2025 12:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Introducing Dirigo โ€“ Post #3: Hardware extensibility & the Digitizer interface Iโ€™m writing weekly posts to introduce Dirigo, a flexible image acquisition framework for Python. In the last post, I introduced the reconfigurable acquisition pipeline. In this post, Iโ€™ll describe har...

๐Ÿ”ฌ New post in the "Introducing Dirigo" series! (my project to build a flexible backend for sci. image acquisition)

This week: the Digitizer interfaceโ€”how to abstract the main data-collection device in laser-scanning microscopy to support different cards through a single, oscilloscope-inspired API.

25.08.2025 14:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Video thumbnail

New post in the "Introducing Dirigo" series!

In this one, I share a short video clip demo & walk through how Dirigo organizes image acquisition as a reconfigurable dataflow graph.

๐Ÿ‘‰ forum.image.sc/t/introducin...

19.08.2025 15:46 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Designing Dirigo: a flexible, extensible backend for scientific image acquisition Some time ago, on a certain social platform that has since been renamed, I asked for suggestions on laser scanning microscopy acquisition control software. I was looking for something in the spirit of...

Just posted Part 1 of a new series on "Dirigo", my design for a very flexible, extensible backend for scientific image acquisition.

Iโ€™ll be posting weekly to spark feedback and find collaborators.
This first post covers the intro & high-level design. ๐Ÿ‘‡

11.08.2025 17:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Where engineers launch and sell the world's best hardware Bringing original, useful, respectful open hardware into existence.

I see strides being made in open source electronics www.crowdsupply.com may be easier here because scalability (PCB fab, pick and place, etc). What would this look like for a microscope frame?

13.02.2025 16:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

'Open source' is a great concept--but I think the bottleneck is fabrication. We need a low-cost partner building open designs at reasonable scale. Open source works so well for software because the 'fabrication' is simply computer execution (+/-compiling and distribution).

13.02.2025 16:19 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

So much fun writing a K99 through this..

28.01.2025 13:31 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Do you think it's trolling you (which would be kinda brilliant) or is this really its best shot?

28.01.2025 13:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Don't sleep on Strava

02.12.2024 14:27 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
GitHub - tweber225/atsbindings: Python bindings for AlazarTech API. Python bindings for AlazarTech API. Contribute to tweber225/atsbindings development by creating an account on GitHub.

I just made my Alazar digitizer Python bindings public. Provides API binding, a ton of enumerations with helper methods, and data parsing.
github.com/tweber225/at...

26.11.2024 23:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@timweber is following 20 prominent accounts