MP Foster Lab @ The Ohio State University's Avatar

MP Foster Lab @ The Ohio State University

@fosterlab.bsky.social

Mark Foster lab in the Department of Chemistry and Biochemistry at The Ohio State University. We biophysical tools to study protein and nucleic acid structure, function, dynamics and interactions. https://go.osu.edu/fosterlab

228 Followers  |  143 Following  |  26 Posts  |  Joined: 23.11.2024  |  1.9516

Latest posts by fosterlab.bsky.social on Bluesky

When visiting our expansive campus, you might agree that your meeting schedule requires careful route planning and opportunities for sightseeing? =D

08.11.2025 16:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The headline invites the interpretation that 20% of chemists admit to falsification to satisfy a reviewer. That is not what the C&EN article states, nor the conclusion from the original source. Since many will only read the headline, I find it misleading.

22.10.2025 18:17 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This headline is misleading and sows doubt in the integrity scientists.

21.10.2025 17:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Kotaro received the 2025 Innovators in Healthcare and Life Sciences Award from Business First!

06.10.2025 00:53 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The USDA has a message for you...

06.10.2025 13:12 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great Plains Regional Annual Symposium on Protein NMR & Integrated Structural Biology, October 17-18, Iowa State University, Ames, IA

Early-bird registration discount ends September 25

Best Oral Presentation & Travel Award Submission Deadline September 25

#NMRchat 🧲

24.09.2025 14:02 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Resonancia MagnΓ©tica Nuclear, herramienta contra el fraude | La Rioja La EstaciΓ³n EnolΓ³gica de Haro ha afianzado la tΓ©cnica de control de calidad y de lucha contra el sabotaje de marca en el sector del vino

RT Héctor Busto @hebusto.bsky.social Resonancia Magnética Nuclear, herramienta contra el fraude. La Estación Enológica de Haro ha afianzado la técnica de control de calidad y de lucha contra el sabotaje de marca en el sector del vino #NMRchat 🧲🍷 @brukercorporation.bsky.social

02.09.2025 18:58 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Arginine dynamics probed by magic-angle spinning NMR with a specific isotope-labeling scheme The specific introduction of 1H-13C or 1H-15N moieties into otherwise deuterated proteins holds great potential for high-resolution solution and magic…

Team effort with @darjarohden.bsky.social πŸ’ͺπŸΌπŸ‘©β€πŸ”¬ targeting my second favourite amino acid by solid-state NMR. Many motion timescales accessible. And the next amino acid is already in the crosshairs (my third favourite 😏).

share.google/Q1ZzwJwDjjwA...

(yeah nothing beats tryptophan)

02.09.2025 16:20 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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Application of NMR to Large RNAs Heteronuclear NMR methodologies developed over the past 40 years have enabled atomic level insights into the solution-state structure and dynamics of …

Journal of Molecular Biology (open) Review Article, Application of NMR to Large RNAs, Brian D. Grossman, Jan Marchant*, Michael F. Summers* www.sciencedirect.com/science/arti... #NMRchat 🧲

31.08.2025 13:39 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Wikipedia:Signs of AI writing - Wikipedia

Wikipedia editors trying to fend off the onslaught of AI crap have crowdsourced some telltale signs of LLM-generated writing; it might be handy for editors and proofreaders generally. Thanks to @ellenrykers.com for pointing me to it. en.wikipedia.org/wiki/Wikiped...

31.08.2025 23:58 β€” πŸ‘ 1267    πŸ” 660    πŸ’¬ 7    πŸ“Œ 82

NMRFx: Integrated Software for NMR Data Processing, Visualization, Analysis and Structure Calculation https://www.biorxiv.org/content/10.1101/2025.08.26.672401v1

29.08.2025 23:46 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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NMR TITAN user survey This survey aims to assess the impact of NMR TITAN on biomolecular research and identify priorities for future development. The form should take approximately 5 minutes to complete. Your responses may...

I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat

28.08.2025 14:13 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
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BPS2026 Annual Meeting | Biophysical Society The BPS2026 Annual Meeting in San Francisco will showcase Biophysics by the Bay, highlighting the exciting advances in science and technology brought forth by big data and AI. Β This year’s program…

Get important feedback from your community and move your work forward. Share your research at #bps2026!

Submit an abstract today buff.ly/oOjstk6

27.08.2025 12:01 β€” πŸ‘ 12    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Listen carefully: Teaching students to navigate science-scepticism Science no longer enjoys unlimited and universal trust. An array of groups are questioning scientific wisdom. What does this mean for students and researchers? Gabriel Dorthe studies how trust and mis...

How should scientists respond to groups that reject, reinterpret or claim scientific findings for their own political purposes?

19.08.2025 07:33 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin - Scientific Reports Scientific Reports - Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin

Grace developed a virtual screening approach focused on cavities identified in the (NPSL2) RNA structure. She then validated screening "hits" experimentally.
Importantly, this approach is broadly applicable to any RNA with a known 3D structure.

14.08.2025 15:26 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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⏰Join us for the NMR Symposium, Nov 26–27, 2025, celebrating our new 1.2 GHz NMR spectrometer. To present a poster, send your abstract to NMR2025@fmp-berlin.de. Registrations are open until September 15th!

14.08.2025 08:07 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps LΓΆvestam and Scheres present a cryo-EM structure of vault particles, found during tau filament extraction from progressive supranuclear palsy (PSP) brain tissue. They reveal a symmetry shift at the va...

Sofia LΓΆvestam's vault structure is now online in Structure @cellpress.bsky.social. πŸ₯³

How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.

www.cell.com/structure/fu...

12.08.2025 16:05 β€” πŸ‘ 126    πŸ” 30    πŸ’¬ 3    πŸ“Œ 0
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42 U.S. Code Β§ 284 - Directors of national research institutes

Last week's EO is in clear violation of federal law that gives Institute Directors e.g., the Director of NINDS or NIGMS etc, the final decision making authority in issuing grants of more than $50,000. The Institute Directors know this.

See b), 3), a)

www.law.cornell.edu/uscode/text/...

1/

11.08.2025 16:03 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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A BRIEF HISTORY OF NUCLEAR MAGNETIC RESONANCE

After receiving the sad news about the passing of Edwin Becker, I ran across his report in Analytical Chemistry titled "A Brief History of Nuclear Magnetic Resonance". It is a well-written piece that will entertain the magnetic resonance enthusiast. #chemsky #NMRsky pubs.acs.org/doi/abs/10.1...

08.08.2025 23:12 β€” πŸ‘ 10    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Seedless: on-the-fly pulse calculation for NMR experiments - Nature Communications The authors develop a computational tool to design NMR pulses, based on the GRadient Assisted Pulse Engineering approach, that can calculate optimal pulse shapes on the fly during the measurements, to...

Nature Communications (open) Seedless: on-the-fly pulse calculation for NMR experiments, Charles J. Buchanan, Gaurav Bhole, Gogulan Karunanithy, Virginia Casablancas-Antràs, Adeline W. J. Poh, Benjamin G. Davis, Jonathan A. Jones* & Andrew J. Baldwin* www.nature.com/articles/s41... #NMRchat #NMR 🧲

08.08.2025 14:03 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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RFK Jr. pulls $500 million in funding for vaccine development Twenty-two projects, totaling $500 million, to develop vaccines using mRNA technology will be halted, the health secretary announced. β€œI don’t think I’ve seen a more dangerous decision in public healt...

It’s difficult to overstate just how reckless and incompetent this is.

mRNA technology saved millions of lives during the COVID-19 crisis. Now, RFK Jr. is undermining the science that could protect us from the next pandemicβ€”and putting American lives at risk.

07.08.2025 17:38 β€” πŸ‘ 168    πŸ” 47    πŸ’¬ 18    πŸ“Œ 1

Negotiating with terrorists? This sure looks like a hostage situation.

06.08.2025 00:13 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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How to get helpful help Chemical & Engineering News (C&EN): Keeping you up to date with the chemistry news that matters most. Published by the American Chemical Society.

Asking for help is not admitting failure, but rather using your resources to ensure that expectations are met. Knowing how to ask for help ensures that you get help that is actually useful, or even crucial, in meeting your goals. cen.acs.org/careers/care... #chemsky

05.08.2025 20:15 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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4.6.0 Today, I’d like to announce Homebrew 4.6.0. The most significant changes since 4.5.0 are opt-in concurrent downloads with HOMEBREW_DOWNLOAD_CONCURRENCY, preliminary macOS 26 (Tahoe) support and a buil...

🍺 Homebrew 4.6.0 is out!

Opt-in concurrent downloads (`HOMEBREW_DOWNLOAD_CONCURRENCY`), early macOS 26 (Tahoe) support, a built-in `brew mcp-server` and lots of other fixes.

Run `brew update` to get it.

Full details at: brew.sh/2025/08/05/h...

05.08.2025 10:24 β€” πŸ‘ 34    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0
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Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR Microsecond-to-millisecond motions are instrumental for many biomolecular functions, including enzymatic activity and ligand binding. Bloch-McConnell Relaxation Dispersion (BMRD) Nuclear Magnetic Reso...

Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR, Ben P. Tatman*, Vidhyalakshmi Sridharan, Motilal Uttarkabat, Christopher P. Jaroniec, Matthias Ernst, Petra Rovó, Paul Schanda* pubs.acs.org/doi/10.1021/... #NMRchat 🧲

02.08.2025 16:19 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Jennifer Doudna is named 2026 Priestley Medalist The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky πŸ§ͺ

02.08.2025 16:08 β€” πŸ‘ 129    πŸ” 31    πŸ’¬ 4    πŸ“Œ 3
conference poster

conference poster

The 64th Annual Rocky Mountain Conference on Magnetic Resonance (RMCMR) EPR Symposium will take place August 3-7, 2025 at the Snowbird Resort & Conference Center, Snowbird, Utah rockychem.com #NMRchat #NMR #NMRevents #ESR #EPR 🧲

20.12.2024 17:37 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2
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Simultaneous ligand binding to intact and partially formed ATP binding sites in the hexameric termination factor Rho Thermodynamic coupling between ligand binding sites affords macromolecular machines a means to coordinate processive function. Because these machines may be compositionally complex, quantifying and in...

Our love affair with native mass spectrometry for studying protein-ligand interactions continues...
www.biorxiv.org/cgi/content/...

24.07.2025 18:03 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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How Trump’s D.E.I. Cuts Are Hurting Rural White Americans Too

Explore this gift article from The New York Times. You can read it for free without a subscription. www.nytimes.com/2025/07/10/u...

10.07.2025 11:48 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Helium recycling for sustainable science, supported by #nigms and #osu

08.07.2025 15:19 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@fosterlab is following 20 prominent accounts