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Rachel Gottschalk

@gottschalklab.bsky.social

Systems Immunology and Macrophage Signaling Assistant Professor at U Pitt

1,003 Followers  |  575 Following  |  11 Posts  |  Joined: 14.11.2024  |  2.0378

Latest posts by gottschalklab.bsky.social on Bluesky

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49 travel grants awarded! πŸŽ‰
These early-career scientists are going to absolutely crush it at Cytokines 2025. The future of cytokine biology is looking bright with talent like this!
Check out all the recipients: cytokinesociety.org/2025/08/29/2...
#CytokineSociety #Cytokines2025 #NextGenScientists

03.09.2025 19:01 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
Three former MIDS scholars stand in a group along with Drs. Olivera Finn and Partha Biswas.

Three former MIDS scholars stand in a group along with Drs. Olivera Finn and Partha Biswas.

Do you know an undergrad at Pitt, Chatham University, or @cmu.edu who hasn't had opportunities for hands-on research? Please encourage them to apply for the Microbiology and Immunology Departments (MID) Scholars Program! Learn more and apply: lnkd.in/eT-gYTqR

29.10.2025 12:22 β€” πŸ‘ 5    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0
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Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.

Want to get a tough sample, like lung, looking like this? Read more!

www.biorxiv.org/content/10.1...

28.10.2025 08:05 β€” πŸ‘ 86    πŸ” 40    πŸ’¬ 3    πŸ“Œ 4
Stanford | Faculty Positions: Details - Assistant Professor of Molecular and Cellular Physiology

Molecular & Cellular Physiology (MCP) Monday

We are recruiting a tenure-track assistant professor to join the Dept of Molecular & Cellular Physiology at Stanford. Apply to be our colleague 1/n
facultypositions.stanford.edu/en-us/job/49...

27.10.2025 23:33 β€” πŸ‘ 36    πŸ” 33    πŸ’¬ 2    πŸ“Œ 1
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Faculty Positions The Sloan Kettering Institute is seeking innovative scientists to join our faculty.

My institution---the Sloan Kettering Institute, the basic science arm of the Memorial Sloan Kettering Cancer Center---is hiring new faculty this cycle! Applications close Nov 15.

www.mskcc.org/research/ski...

27.10.2025 14:45 β€” πŸ‘ 17    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0
Graphic announcing that the Center for Systems Immunology and the University of Pittsburgh Department of Immunology are hiring an Assistant Professor in Systems Immunology. To learn more or apply, visit join.pitt.edu and search 24007498 under Faculty Positions

Graphic announcing that the Center for Systems Immunology and the University of Pittsburgh Department of Immunology are hiring an Assistant Professor in Systems Immunology. To learn more or apply, visit join.pitt.edu and search 24007498 under Faculty Positions

🚨 Faculty position alert! 🚨The Center for Systems Immunology (CSI) and @pitt-immunology.bsky.social are seeking to appoint a tenure-stream Assistant Professor. Learn more and apply: bit.ly/3L42cGS

20.10.2025 15:42 β€” πŸ‘ 5    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0
Assistant Professor - CSI Click the link provided to see the complete job description.

The Center for Systems Immunology at the University of Pittsburgh is recruiting at the Assistant Professor level. See below for more information. Please repost! cfopitt.taleo.net/careersectio...

16.10.2025 14:28 β€” πŸ‘ 11    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!

apply.interfolio.com/174756

14.10.2025 17:35 β€” πŸ‘ 129    πŸ” 95    πŸ’¬ 2    πŸ“Œ 5
Morgan Symone Jackson-Strong will defend her thesis "Investigating the regulatory roles of CD36 and GATA2 in the immunometabolic, transcriptomic, and functional programming of alveolar macrophages" on November 6, 2025 at 1 pm at The Assembly.

Morgan Symone Jackson-Strong will defend her thesis "Investigating the regulatory roles of CD36 and GATA2 in the immunometabolic, transcriptomic, and functional programming of alveolar macrophages" on November 6, 2025 at 1 pm at The Assembly.

Congratulations to Morgan Jackson-Strong from the @gottschalklab.bsky.social who will defend her thesis in a few weeks! πŸ‘

14.10.2025 21:00 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Reposting, submit soon!

08.10.2025 00:16 β€” πŸ‘ 11    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

05.10.2025 12:03 β€” πŸ‘ 62    πŸ” 71    πŸ’¬ 2    πŸ“Œ 1
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Great minds think unalike: Learn how a team of immunologists, cancer researchers, telomere experts, and an organic chemist brought their different expertise together to reveal new insights into how damage to #telomeres can shut down #cancer -fighting T cells. buff.ly/gICm1SL (1/2)

02.10.2025 14:38 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

We are currently in the process of recruiting a technician. πŸ₯ΌπŸ­πŸ”¬

If you know anyone with enthusiasm to learn new skills and stamina to hear me go on and on about IFNs, please have them reach out to me for more details!

02.10.2025 17:41 β€” πŸ‘ 16    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0
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Assistant Professor of Biochemistry at Vanderbilt University - Nashville, Tennessee job with Vanderbilt University School of Medicine | 12843515 Department of Biochemistry, School of Medicineβ€”Basic Sciences

If you are somehow still compelled to be a PI in the world in which we find ourselves, we'd love to have you as a colleague!

Two positions in Biochemistry at Vanderbilt University.

www.nature.com/naturecareer...

www.nature.com/naturecareer...

02.10.2025 19:23 β€” πŸ‘ 15    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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πŸ‘‹ Hello Bluesky! We are the Pitt Department of Immunology. From autoimmune disease and cancer immunotherapy to vaccine development to infectious disease, our work spans the spectrum of immunological science. Follow along for updates on the latest publications and other news!

24.09.2025 18:09 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Excellent opportunity - the Kueh lab will be recruiting at the Yale Center for Systems and Engineering Immunology this fall.

19.08.2025 18:46 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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πŸ›‘οΈHow do macrophages tailor their defenses to different pathogens? Our new paper in @cp-cellsystems.bsky.social combines dense multi-omics time series with high‐content CRISPR screens (CROP-seq) to map the regulatory landscape underlying macrophage immune responses: www.cell.com/cell-systems... (1/9)

12.08.2025 16:43 β€” πŸ‘ 13    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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GM-CSF derived from alveolar type 2 cells promotes CD301b+ cDC2 generation and allergic airway inflammation AT2 cell–derived GM-CSF is essential for establishing a terminally differentiated CD301b+ lung cDC2 compartment and type 2 immunity.

AT2 cell–derived GM-CSF is essential for establishing a terminally differentiated CD301b+ lung cDC2 compartment and type 2 immunity @sciimmunology.bsky.social
www.science.org/doi/10.1126/...

08.08.2025 18:18 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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MSA Pairformer efficiently extracts structure, protein-protein interactions, and mutation effects from MSAs by decomposing the effects of phylogeny and structural contacts.

@yoakiyama.bsky.social Zhidian Zhang @milot.bsky.social @martinsteinegger.bsky.social @sokrypton.org

05.08.2025 21:17 β€” πŸ‘ 32    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Good news for NIH MIRA applicants. Grants.gov recently published the forecast notice for the reissuance of the EI/NI MIRA notice of funding opportunity. As indicated at the link, the estimated post date for the NOFO is Nov 3. www.grants.gov/search-resul...

05.08.2025 17:51 β€” πŸ‘ 31    πŸ” 16    πŸ’¬ 0    πŸ“Œ 0

Yay! Congratulations.

05.08.2025 02:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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ICYMI: Parsing the STING in pulmonary hypertensionβ€”

Andrew J. Bryant & team report on opposing roles for STING in PHβ€”a paradigm shifting mechanism suggesting we refocus on treatments that target cell-specific inflammatory activation: buff.ly/DWmLPLp

19.07.2025 15:13 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
NOT-OD-25-132: Supporting Fairness and Originality in NIH Research Applications NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supporting Fairness and Originality in NIH Research Applications NOT-OD-25-132. NIH

NIH is already feeling the effects of LLMs.

A new policy was posted yesterday that limits the number of proposals that can be submitted by any one investigator.

grants.nih.gov/grants/guide...

18.07.2025 17:17 β€” πŸ‘ 71    πŸ” 21    πŸ’¬ 1    πŸ“Œ 4
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Junior, Assistant, or Associate Specialist – Xue Lab University of California, Irvine is hiring. Apply now!

The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601

17.07.2025 20:32 β€” πŸ‘ 116    πŸ” 112    πŸ’¬ 0    πŸ“Œ 3
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Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids Gastruloids are three-dimensional stem-cell-based models that recapitulate key aspects of mammalian gastrulation, including formation of an anterior-posterior (AP) axis. However, we do not have detail...

This is such a cool paper and dataset from lab of @arjunraj.bsky.social. There are [ahem] a lot of spatial transcriptomics papers out there. Here's a [rare?] example of one from which we can truly learn some interesting things...

www.biorxiv.org/content/10.1...

18.07.2025 20:50 β€” πŸ‘ 31    πŸ” 5    πŸ’¬ 2    πŸ“Œ 0
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Regulation of inflammatory responses by pH-dependent transcriptional condensates Inflammation is an essential defense response but operates at the cost of normal tissue functions. Whether and how the negative impact of inflammation…

Exciting week! Congrats to @xuzhoulab.bsky.social, Ruslan Medzhitov, & coauthors on discovering a new mechanism to regulate inflammation!! πŸŽ‰ www.sciencedirect.com/science/arti...

18.07.2025 23:14 β€” πŸ‘ 27    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
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Plasma proteomics links brain and immune system aging with healthspan and longevity - Nature Medicine In a large-scale proteomic study of biological aging of 11 organs from 44,498 individuals in the UK Biobank, the biological ages of the brain and immune system emerged as strong predictors of healthsp...

'In the present study, we found evidence that the brain and immune system may be central regulators of aging and longevity in humans, as aged brains are most strongly predictive of earlier mortality, and youthful brains and immune systems are uniquely predictive of longevity.'

16.07.2025 17:14 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

My NIH diversity supplement was reinstated! πŸ₯³

This is not the time to keep quiet or feel defeated by this administration. This is the time to raise hell πŸ”₯ and be heard ✊🏽

14.07.2025 19:14 β€” πŸ‘ 323    πŸ” 58    πŸ’¬ 7    πŸ“Œ 1
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Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...

#WeekendRead! #InterferonsFriendsOrFoes?! @ruthfranklinlab.bsky.social, Medzhitov, Hoagland, Rodriguez-Morales &co show @science.org that macrophage-derived oncostatin M overcomes type I IFN detrimental responses during severe influenza lung infection by driving AT-II epithelial cell proliferation!

12.07.2025 14:10 β€” πŸ‘ 30    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression.

Our lab just completed a +6 year #marathon, describing for the first time that the #microbiome is critical for #exercise - induced increases in antitumor CD8 T cell immunity and improved of #cancer #immunotherapy.
www.cell.com/cell/fulltex...

09.07.2025 18:12 β€” πŸ‘ 25    πŸ” 10    πŸ’¬ 2    πŸ“Œ 1

@gottschalklab is following 20 prominent accounts