Clement Tsui PhD 🇭🇰 🇨🇦

Didn't aware of this fascinating discovery till now. #fungi
Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | Science www.science.org/doi/full/10....

Postglacial History of a Widespread Wood‐Decaying Fungus in Europe Suggests Migration out of Multiple Refugia Followed by Admixture While postglacial migration patterns have been well-studied in plants and animals in Europe, the same is not true for microorganisms such as fungi, and it remains unclear whether fungi have followed ...

Postglacial History of a Widespread Wood‐Decaying Fungus in Europe Suggests Migration out of Multiple Refugia Followed by Admixture onlinelibrary.wiley.com/doi/10.1111/...

The peer-review crisis: how to fix an overloaded system Journals and funders are trying to boost the speed and effectiveness of review processes that are under strain.

As a writer, teacher, AE, and reviewer, i share lots of their views. We need to work together to improve the system.
The peer-review crisis: how to fix an overloaded system www.nature.com/articles/d41...

Pangeneric analyses reveal the divergent genome evolution and ecologies between morels and truffles in the Morchellaceae Morels are iconic macrofungi known for their culinary value and spring emergence. Molecular phylogenetic studies have hitherto failed to elucidate the…

Pangeneric analyses reveal the divergent genome evolution and ecologies between morels and truffles in the Morchellaceae www.sciencedirect.com/science/arti...

Multi‐Omics Analysis of Experimentally Evolved Candida auris Isolates Reveals Modulation of Sterols, Sphingolipids, and Oxidative Stress in Acquired Amphotericin B Resistance An overview of resistance mechanisms in two East Asian Candida auris isolates evolved in vitro. The A1.1 strain acquired resistance by enhancing oxidative stress responses through the AOX2, RTG3, and...

Multi‐Omics Analysis of Experimentally Evolved #Candida auris Isolates Reveals Modulation of Sterols, Sphingolipids, and Oxidative Stress in Acquired Amphotericin B Resistance onlinelibrary.wiley.com/doi/10.1111/...

Does the use of topical azoles have an impact on antifungal resistance? Pathogenic fungi have an increasing impact on human health but their study, control or prevention is often a low priority in many health systems. It has be

Does the use of topical azoles have an impact on antifungal resistance? url: academic.oup.com/jac/article/...

Plasmid-like dynamics of persistent RNA viruses in the host fungal population | Journal of Virology While RNA viruses are generally known for their ability to infect cells from the extracellular environment, a substantial diversity of RNA viruses, particularly those that persistently infect fungi, l...

Plasmid-like dynamics of persistent RNA viruses in the host fungal population | Journal of Virology journals.asm.org/doi/10.1128/...

Infections as ecosystems: community metabolic interactions in microbial pathogenesis | Infection and Immunity Microbial communities are present on nearly every surface of the human body. These microbiomes exist as dynamic ecosystems that are influenced by heterogeneous nutritional and chemical landscapes, the...

Excited to have our new mini review on Microbiome Metabolism out today in I&I as part of the @asm.org New Voices in Microbiology collection! Check it out!

🧫🧪

journals.asm.org/doi/10.1128/...

How many plasmids can bacteria carry? A synthetic biology perspective | Open Biology Plasmids are pinnacle tools in synthetic biology and other biotechnological applications. They serve as the simplest approach to introduce recombinant DNA, which is then transcribed into RNA that func...

How many #plasmids can #bacteria carry? royalsocietypublishing.org/doi/10.1098/...

Our body is a mosaic of fungi. Some scientists think they could be influencing our brain The fungi within our bodies may have a much greater effect on our health than we've long given them credit for.

www.bbc.com/future/artic...

Evolution and evolvability of rifampicin resistance across the bacterial tree of life | PNAS Predicting the ability of bacteria to develop antibiotic resistance is challenging, especially for the vast majority of species for which no experi...

Evolution and evolvability of rifampicin resistance across the bacterial tree of life www.pnas.org/doi/abs/10.1... #jcampubs

Weekly Screening of Circulating Mucorales DNA and early treatment in Severely Burned Patients Improves Survival: Real-Life Bi-center Experience in France Early serum Mucorales DNA detection in severely burned patients enables faster diagnosis of invasive wound mucormycosis, reducing 100-day mortality, partic

Weekly Screening of Circulating Mucorales DNA and early
treatment in Severely Burned Patients Improves Survival:
Real-Life Bi-center Experience in France

Emmanuale Faure... Alexandre Alanio and @sarah-delliere.bsky.social 

#IDSky #MedMycoSky #IDDx

academic.oup.com/cid/advance-...

Pleased to say that our preprint benchmarking Nanopore data for MLST, cgMLST, cgSNP & AMR typing from bacterial isolates is out! TL;DR you can get almost perfect results from 50x depth using live SUP basecalling with a GPU in under 20 hours #microsky#IDsky 🦠🧬🖥️ /1
www.medrxiv.org/content/10.1...

Phylogenetic networks empower biodiversity research | PNAS Reticulate evolution has long been recognized as a key mechanism that contributes to genetic and trait diversity. With the widespread availability ...

Phylogenetic networks empower biodiversity research | PNAS www.pnas.org/doi/10.1073/...

On the biological meaning of the population pangenome The prokaryotic pangenome, the full complement of genes within a species, is strikingly large. To understand how ecological forces shape this diversity, it is useful to examine the variable gene pool ...

On the biological meaning of the population pangenome: Trends in Microbiology www.cell.com/trends/micro...

Improved consistency of Candida auris colonization screening with an anterior nares and hands composite sample C. auris colonization screening is important to inform infection control practices. This study included axilla and groin, and anterior nares and hands comp

Improved consistency of Candida auris colonization screening with an anterior nares and hands composite sample url: academic.oup.com/cid/article/...

Brown locusts, Locustana pardalina, host fluconazole resistant Candidozyma (Candida) auris, closely related to Clade III clinical strains Abstract. The environmental niche and mode of transmission from the environment to humans of the emerging pathogenic yeast, Candidozyma (Candida) auris is

#Candida auris from insects! amazing!
Brown locusts, Locustana pardalina, host fluconazole resistant Candidozyma (Candida) auris, closely related to Clade III clinical strains url: academic.oup.com/mmy/article/...

Very nice work!

Myco-Ed: Mycological curriculum for education and discovery Fungi are important and hyperdiverse organisms, yet chronically understudied. Most fungal clades have no reference genomes, impeding our understanding of their ecosystem functions and use as solutions...

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

Starship giant transposons dominate plastic genomic regions in a fungal plant pathogen and drive virulence evolution Nature Communications - Giant transposons, known as ‘Starships’, mediate horizontal gene transfer between fungal genomes. Here, Sato et al. show that Starships occupy genome regions...

📣 Happy to see the journal publication 📄 of our work on Starships 🚀 in Verticillium fungi: terrific work led by @yukiyosato.bsky.social
rdcu.be/exBSp

Global hotspots of mycorrhizal fungal richness are poorly protected - Nature Machine-learning algorithms trained on 25,000 geolocated soil samples are used to create high-resolution global maps of mycorrhizal fungi, revealing that less than 10% of their biodiversity hotspots a...

Global hotspots of mycorrhizal fungal richness are poorly protected www.nature.com/articles/s41... #jcampubs

The extended mobility of plasmids Abstract. Plasmids play key roles in the spreading of many traits, ranging from antibiotic resistance to varied secondary metabolism, from virulence to mut

extended mobility of plasmids url: academic.oup.com/nar/article/...

White-Brown switching controls phenotypic plasticity and virulence of Candida auris Using transcriptomics and reverse genetics, Phan-Canh et al. present a comprehensive analysis of genes governing phenotypic White-Brown switching in the multidrug-resistant fungal pathogen Candida aur...

White-Brown switching controls phenotypic plasticity and virulence of #Candida auris: Cell Reports www.cell.com/cell-reports...

International consensus statement on microbiome testing in clinical practice There is growing interest in the potential exploitation of the gut microbiome as a diagnostic tool in medicine, but evidence supporting its clinical usefulness is scarce. An increasing number of comme...

International consensus statement on microbiome testing in clinical practice - The Lancet Gastroenterology & Hepatology www.thelancet.com/journals/lan...

Anthropogenic activity and climate change exacerbate the spread of pathogenic bacteria in the environment Climate change and human activity will increase global richness and abundance of pathogenic bacteria, threatening public health.

doi.org/10.1126/scia...

Assistant/Associate/Full Professor (Botany & Plant Pathology) The Department of Botany and Plant Pathology invites applications for a full-time (1.00 FTE), 9-month, tenure-track or tenured Assistant, Associate, or Full Professor position.Any hiring at the rank o...

We're hiring an Assistant/Associate/Full Professor and Director for our amazing, newly renovated herbarium!

jobs.oregonstate.edu/postings/170...

How does the sewer microbiome impact wastewater surveillance for antibiotic resistance? Antibiotic resistance is a global health threat that is difficult to directly monitor prior to clinical presentation. Wastewater surveillance has emer…

Interesting review on the contribution of resident bacteria in sewage infrastructure and how they can potentially skew wastewater monitoring efforts on AMR

www.sciencedirect.com/science/arti...

A Roadmap of Primary Pandemic Prevention Through Spillover Investigation Roadmap of Primary Pandemic Prevention

wwwnc.cdc.gov/eid/article/...

QTL identification and characterization of the recombination landscape of the mountain pine beetle (Dendroctonus ponderosae) Abstract. Insect pests can rapidly accumulate in number and thrive in diverse environments, making them valuable models for studying phenotypic plasticity

QTL identification and characterization of the recombination landscape of the mountain pine beetle (Dendroctonus ponderosae) url: academic.oup.com/g3journal/ar...

How to interpret MICs of amphotericin B, echinocandins and flucytosine against Candida auris (Candidozyma auris) according to the newly established EUCAST breakpoints - Clinical Microbiology and Infection www.clinicalmicrobiologyandinfection.com/article/S119...