Clement Tsui PhD 🇭🇰 🇨🇦

We're hiring a #postdoc with knowledge of the #microbiome, #microbiology, #bioinformatics, #computationalbiology to understand the role of the vaginal microbiome in women's health. #Baltimore #womenshealth

Genetic and environmental control of parasexual reproduction in the pathogenic Candida species | Microbiology and Molecular Biology Reviews SUMMARYCandida species are major yeast pathogens that cause both mucosal candidiasis and life-threatening invasive infections. Most Candida species, including Candida albicans, have long been thought ...

Genetic and environmental control of parasexual reproduction in the pathogenic #Candida species | Microbiology and Molecular Biology Reviews journals.asm.org/doi/abs/10.1...

mGem: Submarine mycology—an analog to astromycology | mBio Astromycology, the study of fungi in space environments, has emerged as a critical field for understanding both their risks and potential applications (1). Among the most pressing concerns is the prot...

sounds scary!
mGem: Submarine #mycology—an analog to astromycology | mBio journals.asm.org/doi/10.1128/...

Everyone losers 🥲

Are you a PhD student ready to publish a paper? Submit your research to our journal today & enter one of our new journal prizes, celebrating PhD student work in #Botany or #Biology !🧪🌍👇
academic.oup.com/biolinnean/p...
@linneansociety.bsky.social

Dual transposon sequencing profiles the genetic interaction landscape in bacteria Gene redundancy complicates systematic characterization of gene function as single-gene deletions may not produce discernible phenotypes. We report dual transposon sequencing (dual Tn-seq), a platform...

This week @science.org Dual #transposon sequencing profiles the #genetic interaction landscape in #bacteria | Science www.science.org/doi/10.1126/... 🦠🔬🧫🧬

Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris | Antimicrobial Agents and Chemotherapy In 2019, the Centers for Disease Control and Prevention (CDC) designated Candidozyma auris (previously known as Candida auris) as an urgent antimicrobial threat, making it the first fungal pathogen to...

Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris | Antimicrobial Agents and Chemotherapy journals.asm.org/doi/full/10....

Dynamic airborne mycobiome in the metropolitan city transit system is driven by seasonality and station type | Microbiology Spectrum Respiratory infections and allergic reactions caused by airborne fungi have received considerable public attention; however, fungal communities remain poorly investigated. This research performed the ...

Dynamic airborne mycobiome in the metropolitan city transit system is driven by seasonality and station type | Microbiology Spectrum journals.asm.org/doi/10.1128/...

Gut fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates Fungi in the gut microbiome (the "mycobiome") are a neglected component of the human holobiont. This study of gut fungal profiles across natural populations of humans and non-human primates reveals si...

Gut #fungal profiles reveal phylosymbiosis and codiversification across humans and nonhuman primates dx.plos.org/10.1371/jour...

Complex Genomic Landscape of Inversion Polymorphism in Europe's Most Destructive Forest Pest url: academic.oup.com/gbe/article/...

wow, what a mess! Blessings

How sequencing technology shapes our understanding of river water microbiomes and resistomes: a comparative study journals.asm.org/doi/full/10.... #jcampubs

We have a new paper out in Molecular Ecology, led by @devinbendixsen.bsky.social ! Reproductive isolation due to divergent ecological selection is accompanied by vast genomic instability in experimentally evolved yeast populations onlinelibrary.wiley.com/doi/10.1111/...

Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor Zhang et al. identify STOM, a previously unknown fungal MAMP, and its receptor-co-receptor pair, STOMR/STOMRh. The evolutionary loss of functional STOMRh in monocots restricts immune recognition, whil...

Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor: Cell Host & Microbe www.cell.com/cell-host-mi...

How Klebsiella pneumoniae controls its virulence The bacterial pathogen Klebsiella pneumoniae is a serious public health threat due to its propensity to develop antimicrobial resistance (AMR), the emergence of hypervirulent strains able to cause com...

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

Aquatic fungal diversity assessment through metagenomics is still limited to current databases aslopubs.onlinelibrary.wiley.com/doi/10.1002/... #jcampubs

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Penicillium solitum over 8 years in a cheese cave => green-to-white shift

@currentbiology.bsky.social from @benwolfe.bsky.social with @kellerlab.bsky.social

www.cell.com/current-biol...

Taxon‐specific BLAST percent identity thresholds for identification of unknown sequences using metabarcoding The identification of organisms in environmental samples using metabarcoding relies on factors such as taxonomic assignment methods, genetic markers, reference databases and confidence thresholds ...

📖Published📖

Pappalardo et al. developed taxon-specific confidence thresholds for eukaryotes at different taxonomic levels to optimize the accuracy of BLAST-based taxonomic assignments for metabarcoding 🧬 🌍 🧪 Read more here 👇

Genomic rearrangements at the MAT locus suggest reproductive shifts in Rhodotorula yeasts Rhodotorula, a red yeast genus inhabiting diverse environmental and clinical niches, is a promising microbial source for carotenoid and lipid production. Despite the coexistence of sexual and asexual ...

www.biorxiv.org/content/10.1...

The landscape of microbial associations in human cancer Differences between cancer types, infectious disease, and potential prognostic markers are uncovered by studying microbes within cancer DNA.

The landscape of microbial associations in human cancer | Science Translational Medicine www.science.org/doi/10.1126/...

The dimorphic fungus Talaromyces marneffei: An opportunistic killer in Southeast Asia

Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...

Efficient sequence alignment against millions of prokaryotic genomes with LexicMap - Nature Biotechnology LexicMap uses a fixed set of probes to efficiently query gene sequences for fast and low-memory alignment.

Sometimes you meet absolutely incredible bioinfo-magicians.
It was a huge privilege when @shenwei356.bsky.social
joined our group for a year on an @embl.org sabbatical.
While here, he developed a new way of aligning to
millions of bacteria, called LexicMap 1/n
www.nature.com/articles/s41...

Comparison of carbapenemase-producing Enterobacterales colonizing war-affected children from the Gaza Strip and hospitalized children from a national reference center in Qatar: An observational cohort... To compare the rates and molecular characteristics of carbapenemase-producing Enterobacterales (CPE) from rectal screening swabs in war-affected Pales…

Conflicts drive #AMR! www.sciencedirect.com/science/arti...

An update on clinically relevant, rare, and emerging Candida and Saccharomycotina yeasts that have been recently reclassified from Candida | Clinical Microbiology Reviews SUMMARYMany yeast species causing life-threatening invasive infections that were formerly classified in the genus Candida have been reclassified due to their evolutionary and phylogenetic relationships elucidated by DNA sequencing methods that are ...

An update on clinically relevant, rare, and emerging Candida and Saccharomycotina yeasts that have been recently reclassified from Candida | Clinical Microbiology Reviews journals.asm.org/doi/abs/10.1...

Extracellular vesicles from Distinct Histoplasma capsulatum Strains Modulate Phagocyte Function and Promote Fungal Persistence Fungal extracellular vesicles (EVs) are lipid-bilayer compartments that transport a wide range of molecules, including proteins, polysaccharides, pigments, small metabolites, lipids, and RNA. In funga...

Extracellular vesicles from Distinct Histoplasma capsulatum Strains Modulate Phagocyte Function and Promote Fungal Persistence | ACS Infectious Diseases pubs.acs.org/doi/10.1021/...

Migration and standing variation in vaginal and rectal yeast populations in recurrent vulvovaginal candidiasis - PubMed Vaginal yeast infections are very common, yet we do not understand why some people experience chronic infections when most have a single infection that is successfully treated and cleared. We examined...

#candida albicans #candidisis pubmed.ncbi.nlm.nih.gov/40905696/

thanks.😉

Name changes for fungi of medical importance, 2022–2024 | Journal of Clinical Microbiology Since fungal identification methods based on examination of morphological and phenotypic features are complicated by the astonishing diversity of organisms capable of causing human infections especial...

Name changes for fungi of medical importance, 2022–2024 | Journal of Clinical Microbiology journals.asm.org/doi/10.1128/...

Thanks for putting this together. Happy to join!

The Mycobacterium tuberculosis complex pangenome is small and shaped by sub-lineage-specific regions of difference The accessory genome of Mycobacterium tuberculosis is small, but differences in gene content are found both between and within lineages.

Our paper on the pangenome of the Mycobacterium tuberculosis complex is now out in its final form (version of record) in eLife! elifesciences.org/articles/97870