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David Tobin

@tobinlab.bsky.social

Scientist at Duke studying tuberculosis, host susceptibility to infection, and mycobacterial pathogenesis. Views are my own and do not represent those of my employer.

2,924 Followers  |  1,267 Following  |  17 Posts  |  Joined: 06.09.2023  |  1.8448

Latest posts by tobinlab.bsky.social on Bluesky

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The pathogenic bacteria Shigella avoids detection inside host cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

Read more in the eLife Insight Article: buff.ly/1mIc6m0

03.12.2025 23:28 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Development's Pathway to Independence Programme Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:

Mentoring
Profile raising
Leadership training
Network building

Spread the word...

www.biologists.com/grants/devel...

03.12.2025 06:56 β€” πŸ‘ 69    πŸ” 84    πŸ’¬ 0    πŸ“Œ 1
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PhD opportunities

if you are interested in a PhD in tuberculosis drug discovery, check out our opportunities πŸ§ͺ🦠 #Tuberculosis lstm.ac/PhD

24.11.2025 15:18 β€” πŸ‘ 6    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
Assistant Professor Applicants should possess a Ph.D. in the biological sciences or related fields.Candidates are expected to document expertise in their specialty by a record of postdoctoral training, peer reviewed publ...

Assistant Professor position posted for my Department, Biological Sciences at UNC Charlotte! Current research foci: Immunology, Microbiology, Virology; Biomolecular Function; Proteostasis; Genome Integrity; Epigenome Regulation; Cancer; Environmental Risks. jobs.charlotte.edu/postings/65141

19.11.2025 14:16 β€” πŸ‘ 28    πŸ” 43    πŸ’¬ 2    πŸ“Œ 1

Don't wait to apply! The deadline is coming up soon...

Come join us! Western Mass is a fantastic place to do science!

20.11.2025 13:24 β€” πŸ‘ 2    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
Early abstract submission now open!

Early abstract submission now open!

Early abstract submissions for ASM Microbe 2026β€”now 3 fully integrated meetings within 1 microbial worldβ€”are officially open. Submit by Dec. 2, 2 p.m. ET to elevate your research, spark new collaborations and join the conversations defining what’s next. asm.org/events/asm-m...

20.11.2025 12:15 β€” πŸ‘ 5    πŸ” 8    πŸ’¬ 1    πŸ“Œ 2

Time to vote for our GSA officers!

Please repost

19.11.2025 19:52 β€” πŸ‘ 9    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...

17.11.2025 23:22 β€” πŸ‘ 67    πŸ” 30    πŸ’¬ 1    πŸ“Œ 3
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The WHO Global tuberculosis report 2025 is out!

TB is the world’s deadliest infectious killer, claiming over 1.2 million lives and affecting an estimated 10.7 million people last year

www.who.int/news-room/re...

13.11.2025 02:51 β€” πŸ‘ 33    πŸ” 23    πŸ’¬ 1    πŸ“Œ 0
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The viral arms race: an interview with Harmit Malik Harmit Malik. Photo credit: Fred Hutchinson Cancer Research Center.Harmit Malik is Professor and Associate Director of the Basic Sciences Division at the Fred Hutchinson Cancer Center in Seattle, WA,…

For our #InfectiousDisease Special Issue we interviewed the marvelous @harmitmalik.bsky.social ! We discussed the #viral arms race, how to support mentees and the beauty of basic science πŸ”¬

journals.biologists.com/dmm/article/...

10.11.2025 14:05 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 3
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Course Offerings | Marine Biological Laboratory

πŸ”¬ Applications are now open!

Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network.

➑️Apply today: go.mbl.edu/courses

28.10.2025 18:08 β€” πŸ‘ 30    πŸ” 30    πŸ’¬ 2    πŸ“Œ 2
Zebrafish in the wild
YouTube video by John Rawls Zebrafish in the wild

Part 6: For decades, the zebrafish has helped scientists unlock the mysteries of genetics, development, & disease. But the fish that power most discoveries have spent generations inside lab tanks. This video captures footage of zebrafish in their natural environment in Nepal.
youtu.be/cCZhZpPALqw

28.10.2025 14:08 β€” πŸ‘ 44    πŸ” 13    πŸ’¬ 0    πŸ“Œ 2
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SCIENTIST – Developmental, Stem Cell & Cancer Biology Program - Toronto (City), Ontario (CA) job with The Hospital for Sick Children - Developmental & Stem Cell Biology Program | 12848200 Discovery-based and/or translational research using model organism genetics and/or stem cell and organoid platforms to study paediatric cancer.

Fantastic opportunity at The Hospital for Sick Children. Please repost. www.nature.com/naturecareer...

28.10.2025 22:05 β€” πŸ‘ 35    πŸ” 41    πŸ’¬ 0    πŸ“Œ 1
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Tenure-Track Assistant Professor Position –AI/ML for Cell Biology - Durham, North Carolina (US) job with Duke University School of Medicine | 12844591 Tenure-Track Assistant Professor Position –AI/ML for Cell Biology

Please repost!!:
We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!!

www.nature.com/naturecareer...

25.10.2025 15:11 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 0    πŸ“Œ 2
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Part 1: The last couple of weeks I've had the pleasure of working with a team of scientists from Duke University, University of Oregon, and Agriculture and Forestry University (AFU) in Nepal to study the biology of zebrafish in their natural habitat. ...

22.10.2025 09:19 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

In this issue:
Β· Interview with @harmitmalik.bsky.social
Β· Interview with Zolelwa Sifumba
Β· Perspective on unravelling Ξ³Ξ΄ T-cell dysregulation in the gut & its implications for immune-mediated diseases
Β· 'At a glance' on engineered bacteriophages
Β· Review on neuroinflammation in fungal infections

21.10.2025 13:14 β€” πŸ‘ 0    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...

19.10.2025 22:28 β€” πŸ‘ 39    πŸ” 18    πŸ’¬ 0    πŸ“Œ 2
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BWF Expands Graduate Diversity Enrichment Program to Support 14 Pre-Doctoral Scholars - Burroughs Wellcome Fund DURHAM, N.C. – The Burroughs Wellcome Fund (BWF) is proud to announce the 2025 recipients of the Graduate Diversity Enrichment Program (GDEP)β€”fourteen outstanding pre-doctoral scientists whose work re...

Congratulations to grad student extraordinaire Kirsten Smith @kms99.bsky.social and all the other awardees @bwfund.bsky.social www.bwfund.org/news/bwf-exp...

17.10.2025 19:19 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!

If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.

Please RT πŸ™

16.10.2025 17:29 β€” πŸ‘ 46    πŸ” 45    πŸ’¬ 0    πŸ“Œ 3
Details - Assistant Professor - Immunology | Human Resources | UMass Amherst

🚨Job posting! #UMassAmherst Department of Veterinary and Animal Sciences is hiring a TT faculty member in #Immunology. Both fundamental and translational areas considered. Please spread the word!
careers.umass.edu/amherst/en-u...

15.10.2025 21:07 β€” πŸ‘ 11    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1
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β€˜It’s a massacre’: CDC battered by government shutdown firings The White House’s mass firing of CDC staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease, according to four people familiar with t...

β€œThe White House’s mass firing of Centers for Disease Control and Prevention staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease.” www.statnews.com/2025/10/11/c...

11.10.2025 19:58 β€” πŸ‘ 94    πŸ” 38    πŸ’¬ 5    πŸ“Œ 3

RIFs at CDC.

Destroying the Epidemic Intelligence Service, NCIRD, NCIPC & a dozen other areas/divisions/branches will cause enormous harm and suffering to America, and indeed to the whole world.

Call your Reps about it.

Then call them again.

11.10.2025 16:09 β€” πŸ‘ 194    πŸ” 100    πŸ’¬ 8    πŸ“Œ 6
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Origin of Ewing sarcoma by embryonic reprogramming of neural crest to mesoderm Using a zebrafish genetic model of Ewing sarcoma, Vasileva et al. provide evidence for a neural crest origin of the disease. These findings offer new insight into how a single oncogenic fusion can hij...

Wonderful collaboration of Claire Arata and co-first-author Elena Vasileva from Amatruda lab. Claire provided the neural crest driver and Elena the EWS oncofusion. Best combination since PB&J. Amazing that expression of a single oncofusion in crest produces ectopic fins.
www.cell.com/cell-reports...

10.10.2025 00:31 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
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We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad:

idm.uct.ac.za/media/739223

09.10.2025 11:28 β€” πŸ‘ 82    πŸ” 40    πŸ’¬ 4    πŸ“Œ 3
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783

07.10.2025 16:10 β€” πŸ‘ 19    πŸ” 30    πŸ’¬ 0    πŸ“Œ 3
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Department of Microbiology | The University of Chicago

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

06.10.2025 17:32 β€” πŸ‘ 19    πŸ” 26    πŸ’¬ 0    πŸ“Œ 0
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The NIH ordered me to stop my β€˜dangerous’ gain-of-function research. It isn’t dangerous at all Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis β€” but the NIH has imposed unfounded stops.

Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com

06.10.2025 12:15 β€” πŸ‘ 42    πŸ” 21    πŸ’¬ 1    πŸ“Œ 5
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Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance Mycobacterium tuberculosis isolates have a complex phylogenetic structure and vary in clinical phenotypes. Combining high-throughput RNA-seq and global population genomics reveals gene expression as an axis of variation in host interaction. Underscoring this, variants in a regulator of a key virulence pathway are associated with increased transmission and drug resistance.

Now online! Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance

30.09.2025 18:51 β€” πŸ‘ 15    πŸ” 2    πŸ’¬ 0    πŸ“Œ 2
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β€˜Completely shattered.’ Changes to NSF’s graduate student fellowship spur outcry The announcement comes months later than usual, leaving many would-be applicants stranded

NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key groupβ€”second-year Ph.D. studentsβ€”is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk

26.09.2025 23:09 β€” πŸ‘ 137    πŸ” 113    πŸ’¬ 2    πŸ“Œ 21
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Eric Peterman @errricpeterman.bsky.social, Jeffrey Rasmussen @jraslab.bsky.social @uwbiology.bsky.social & colleagues discover that microtubules regulate tissue-level navigation in skin-resident macrophages.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...

24.09.2025 08:13 β€” πŸ‘ 31    πŸ” 16    πŸ’¬ 1    πŸ“Œ 1

@tobinlab is following 20 prominent accounts