@mediocre-jake.bsky.social
Postdoc interested in #ubiquitin #lipid #innateimmunity #E3ligases #endoplasmicreticulum https://findaresearcher.wehi.edu.au/chua.n Postdoc (WEHI) https://www.wehi.edu.au/laboratory/feltham-lab/ PhD (UNSW) https://x.com/brownlabunsw?lang=en&mx=
Congrats to Sayan, Michael, Philipp, Ulrike, and everyone else who contributed to this new story! It was an effort of many years; so happy to be included as a part of this study. We hope it will contribute to the development of novel AML and other cancer therapies!
www.science.org/doi/10.1126/...
Learning more about cryptic interaction areas of CRBN during glue binding presented by Lei Liu from Tsinghua University @tsinghuauniversity.bsky.social
Work partially in a pre-print @biorxivpreprint.bsky.social
#AusUb2025 #LorneUbqiuitin2025
@ausub.bsky.social
Very nice presentation by Phil Chamberlain from Neomorph to kick off the TPD day today at @ausub.bsky.social #AusUb2025 #LorneUbiquitin2025
From the fundamentals of glues to identifying more in the proteome to glue
Min Zhuang from ShanghaiTech University talking about the MARCHF5 mitochondria and peroxisome localised E3
#AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social
@impeiyee.bsky.social from the labs of Sylvie Urbe and Michael Clague presents to us a tale of CTLA4 turnover
Some cool stuff published in
@liverpooluni.bsky.social
@jcb.org
#AusUb2025 #LorneUbiquitin2025 @ausub.bsky.social
Eric Bennett coming from
@ucsandiego.bsky.social talks about how E3s have plasticity in quality control to facilitate degradation
#AusUb2025 #LorneUbiquitin @ausub.bsky.social
Always a pleasure to hear about the world of the HECT E3s from @sonjalorenzlab.bsky.social from Max Planck Institute for Multidisciplinary Sciences
Welcome to Australia!
Featuring work published in @cp-molcell.bsky.social @natcomms.nature.com
#LorneUbiquitin2025
#AusUb2025 @ausub.bsky.social
The unique E2/E3 UBE2O structure presented by Kuen-Phon Wu from Academia Sinica Taiwan
#LorneUbiquitin2025 #AusUb2025 @ausub.bsky.social
CTLH E3 ligase coming into action with Toxoplasma infection presented by Chris Tonkin
#LorneUbiquitin2025 #Ubiquitin2025 #AusUb2025
@wehi-research.bsky.social
Day 2 of the conference in Australia
Revisiting the E1-E2-E3 cascade with Chris Lima from the Memorial Sloan Kettering Cancer Center
@ausub.bsky.social
#AusUb2025 #LorneUbiquitin2025
Sir Philip Cohen presenting on the intersection between glycogen metabolism and ubiquitination
From insulin signaling to glycogen
Really appreciate the historical tour of ubiquitin in innate immunity
@ausub.bsky.social
#ubiquitin #AusUb2025 #LorneUbiquitin2025
My favorite topic
ER proteins and protein degradation
Yukio Yoshida from Tokyo Metropolitan Institute of Medical Science
Work shown published in @cp-molcell.bsky.social
#AusUb2025 #LorneUbiquitin2025
@ausub.bsky.social
Fun facts about aryl hydrocarbon receptor presented by @andriigorelik.bsky.social at #AusUb2025 #LorneUbiquitin2025
@ox.ac.uk @ausub.bsky.social
More and more about E3s
Satpal from MRC Protein Phosphorylation and Ubiquitylation Unit talks about remaining E3s
#AusUb2025 #LorneUbiquitin2025
@ausub.bsky.social
#AusUb2025
@ausub.bsky.social
Ubiquitin meets mono-ADP-ribosylation = MARUbylation
Presented by @jnpruneda.bsky.social who came all the way to Australia for the #LorneUbiquitin2025 from Oregon Health & Science University
Hopefully the US visitors have a pleasant stay
Brenda Schulman as the first speaker of #AusUb2025
#LorneUbiquitin2025
Always amazing body of work
@mpibiochem.bsky.social
@ausub.bsky.social
#AusUb2025 starting off with David Komander kicking off the Lorne Ubiquitin meeting in Australia
@ausub.bsky.social
#ubiquitin
Homeostatic control of energy metabolism by monocyte-derived macrophages
@elmiguelche.bsky.social and colleagues show that macrophages sense dysregulated iron metabolism in parenchymal cells and respond by sustaining mitochondrial function in affected cells
www.embopress.org/doi/full/10....
See you all at Lorne for #AusUb2025
On the bus that departed Melbourne airport with a bunch of delegates from around the world that successfully made ut
@ausub.bsky.social
We welcome Dr. Shingo Kajimura to San Antonio this week as our Center for Molecular Metabolism seminar speaker.
19.11.2025 17:23 — 👍 2 🔁 1 💬 0 📌 0
The review by Banani, Lee, Hyman & Rosen (NRMCB 2017) www.nature.com/articles/nrm... on biomolecular condensates has >6000 citations. It…
1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.
Feeling awed and a bit starstruck that @science.org chose to run a book review on #LabworkToLeadership!!
www.science.org/doi/10.1126/...
Di-Gembodies (dimerized nanobodies) for improved and duplexed CryoEM of small and challenging targets!
A collaboration of @cmd.ox.ac.uk, STRUBI, @diamondlightsource.bsky.social, @rosfrankinst.bsky.social
Out now in Nature Chemical Biology @natchembio.nature.com
www.nature.com/articles/s41...
ASBMB's symposium on #proteomics in the life sciences starts on Sunday! What topics are you most excited to learn about? Reply to let us know!
ow.ly/8aJ850WGoTr
Thank you to our sponsors, including: @biognosys.bsky.social, @abseabio.bsky.social, @evosep.bsky.social & @mobilionsystems.bsky.social!
www.nature.com/articles/s41...
An elegant study to use CRISPR technology to optimize the auxin-inducible degron technology
Some interesting observations using the superior degron technology
@natureportfolio.nature.com @nufeinbergmed.bsky.social
📣 First ever international ubiquitin meeting in Australia www.lorneubiquitin.org still accepting abstracts and registrations! Hopefully we can get more people in the Asia-Pacific!
#science #conference #scicomm #Australia
📣 Calling all ubiquitin aficionados - one week to go before abstract deadline (July 18th)!! Join us on the coast in Lorne, Australia. www.lorneubiquitin.org
#ubiquitin
It's been a wild 3.5 years for Philipp, always a pleasure witnessing Philipp's dedication and his journey in the @komanderlab.bsky.social tackling DUB biology in cancer during his PhD journey here @wehi-research.bsky.social
#ubiquitin #science #PhDlife #PhD
A Perspective from Xiaoyu Zhang, Gabriel Simon, and Benjamin Cravatt discusses recent strategies to expand the E3 ligase landscape and the scope of targeted protein
degradation
www.nature.com/articles/s41...
So nice to see @franciscobustos.bsky.social in person this time as a PI
Nice to catch up and see amazing stuff from your lab
More importantly this person remembered me from a dark background while being online in Australia in 2020 but so ashamed I didn't remember #cshlubiq
