@mxhend.bsky.social
Associate Professor Van Andel Institute Focused on neurodegeneration, synuclein, tau
❗🧠 New review in IEEE RBME
How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression
"Network models of neurodegeneration: bridging neuronal dynamics and disease progression"
ieeexplore.ieee.org/document/113...
Exciting study of Alzheimer's plasma biomarkers in a community sample. The finding I was most surprised by was this plot of biomarker prevelance by education. We know education reduces incidence of AD, but this shows it also prevents biological markers of AD! www.nature.com/articles/s41...
22.12.2025 16:56 — 👍 0 🔁 0 💬 0 📌 0Great job, Noah!
14.11.2025 13:01 — 👍 0 🔁 0 💬 0 📌 0
A study by @mxhend.bsky.social and collaborators found that an unstructured layer surrounding the Alzheimer’s-related protein tau plays a critical role in recruiting other proteins to misfold in Alzheimer’s progression. The findings were published in @natcomms.nature.com. www.vai.org/article/not-...
28.10.2025 20:10 — 👍 4 🔁 2 💬 0 📌 0Another graduate student defended! Congratulations, Dr. Goralski!
15.09.2025 15:02 — 👍 6 🔁 1 💬 1 📌 0#proudmentor
20.08.2025 12:35 — 👍 4 🔁 0 💬 0 📌 0
Sjors Scheres
Excellent opportunity for a postdoc to join @sjorsscheres.bsky.social in the LMB’s Structural Studies Division to work on #cryoEM structure determination of amyloid filaments in a lively, multi-disciplinary group.
Read more: www.nature.com/naturecareer...
Closes 03 AUG
#PostdocJobs #ScienceJobs
Excited to have several new lab members join us this year!
20.06.2025 13:52 — 👍 0 🔁 1 💬 0 📌 0
We are thrilled to announce that renowned physician-scientist J. Timothy Greenamyre, M.D., Ph.D., of University of Pittsburgh, will be the recipient of the 2025 Jay Van Andel Award for Outstanding Achievement in Parkinson’s Disease Research!
14.04.2025 20:03 — 👍 4 🔁 3 💬 0 📌 0
Congratulations to grad student Ben for passing his qualifying exam! Now he gets to do all the exciting research he has proposed!
25.03.2025 20:53 — 👍 6 🔁 0 💬 0 📌 0Great collaboration with @sjorsscheres.bsky.social led by graduate student @alysa-kasen.bsky.social! It turns out core filament structure and fuzzy coat PTMs contribute to tau seeding.
13.03.2025 22:22 — 👍 5 🔁 0 💬 0 📌 0
Another first place poster prize for graduate student @alysa-kasen.bsky.social for her work on tau pathology seeding! She is finishing up this summer and looking for a postdoc if anyone needs an excellent scientist!
26.02.2025 19:47 — 👍 4 🔁 1 💬 1 📌 0
2024 has been a year of growth and impact for VAI. Check out our research year in review! ⬇️
30.12.2024 15:53 — 👍 3 🔁 1 💬 0 📌 0
Pharmaceutical company Roche announce that their Phase IIb PADOVA study of the alpha synuclein targeting antibody Prasinezumab just missed its primary endpoint (p=0.0657), but their data suggests possible clinical benefit in early-stage #Parkinsons
www.roche.com/media/releas...
Henderson Lab winter party 2024! Happy holidays everyone!
17.12.2024 18:05 — 👍 11 🔁 3 💬 0 📌 0
