Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit
www.nexperion.net/semcm2026
23.09.2025 10:42 β π 49 π 22 π¬ 0 π 1
βThe Websiteβ is here! It can be intimidating getting into analysis of #CryoET data, and software is evolving all the timeπ©βπ»π. @phaips.vd.st & @florentwaltz.bsky.social put our labβs workflows into an online guide. We hope this helps lower the bar to joining #TeamTomo. Feedback much appreciated! π§ͺπ§Άπ§¬π¬
07.05.2025 10:56 β π 66 π 14 π¬ 2 π 2
1/5: Over the last few months, I have been working on an update for the #FollowRelionGracefully dashboard, which offers improved real-time job previews for #cryoEM #Relion jobs.
27.04.2025 20:49 β π 50 π 20 π¬ 2 π 2
π¦ π§ MemBrain update! π§ π¦
Weβve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics.
π Preprint: doi.org/10.1101/2024...
π Code: github.com/CellArchLab/...
π§΅(1/6) #TeamTomo
25.04.2025 07:28 β π 78 π 34 π¬ 2 π 5
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!π§ͺπ§Άπ§¬πΎ
20.03.2025 22:37 β π 309 π 69 π¬ 16 π 2
ChimeraX can be used to find pockets and cavities in protein structures using the Find Cavities tool or kvfinder command. This feature is available in daily builds from 10 March 2025 or later.
17.03.2025 20:26 β π 59 π 12 π¬ 0 π 1
AreTomoLive: Automated reconstruction of comprehensively-corrected and denoised cryo-electron tomograms in real-time and at high throughput www.biorxiv.org/content/10.1101/2025.03.11.642690v1 #cryoEM
14.03.2025 07:10 β π 7 π 7 π¬ 0 π 0
Stand up for science in Bordeaux
07.03.2025 15:22 β π 27 π 6 π¬ 0 π 0
It looks like Christmas lights !
07.03.2025 09:36 β π 2 π 0 π¬ 0 π 0
Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives pubmed.ncbi.nlm.nih.gov/39971020/ #cryoEM
20.02.2025 12:46 β π 4 π 3 π¬ 0 π 0
π¬Our @haselbachlab.bsky.social with Pavol Harar have developed βFakETβ!
The new method creates βfakeβ electron microscopy images to train AI, reducing manual work in particle identification.
Read the full story: www.imp.ac.at/news/article...
@viennabiocenter.bsky.social
#AI #cryoem #microscopy
12.02.2025 16:15 β π 15 π 6 π¬ 1 π 1
Improvements in LM (top) and EM (bottom) of our micro-sam model (finetuned) compared to the default SAM model.
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool.
www.nature.com/articles/s41...
12.02.2025 11:41 β π 351 π 120 π¬ 11 π 7
CryoCrane, a visualization tool for cryo-EM screening data, aims to provide an intuitive way to visualize micrographs and to speed up data analysis. #CryoEM #SampleOptimization #GridScreening doi.org/10.1107/S205...
11.02.2025 15:49 β π 3 π 1 π¬ 0 π 0
Very happy to share our last preprint where we investigated the vesicular organization of dopamine hub synapses with cryo-CLEM. It is a brain structure that emerges as an important regulator of striatal activity. Many thanks to David Perrais, Etienne Herzog and the lab of @fronzeslab.bsky.social !
12.02.2025 08:27 β π 3 π 2 π¬ 0 π 0
@stevestuwill.bsky.social you posted on π on Dec 5, 2020 this stunning video - why not repeat on π΅bsky ? (sorry, I did)...
"Time-lapse footage of a vampire amoeba: a microscopic organism that feeds on algal cells by breaking through their cell walls and sucking out their insides."
#ProtistsOnSky
05.02.2025 14:56 β π 157 π 55 π¬ 6 π 17
Hey #teamtomo, if you often find yourself using the excellent membrain-seg from @lorenzlamm.bsky.social et al., you might find my napari plugin "napari-segselect" useful. Let's say your tomogram contains the edges of two bacterial cells, each with a membrane and cell wall:
06.02.2025 11:02 β π 37 π 12 π¬ 3 π 1
Home
This site contains the complete version of the Fiji Training Manual that is written and maintained by Cameron Nowell of the Monash Institue of Pharmaceutical Science.
This manual is provided under the...
Answering the call of @haesleinhuepf.bsky.social, Christian Tischer, Pete Bankhead, @kbias.bsky.social @bethcimini.bsky.social
My Fiji training notes are now FAIR. All online in an open format to download and use for teaching and training. All in Google Doc or PDF formats
bit.ly/4hkfEBF
05.02.2025 22:57 β π 65 π 28 π¬ 3 π 2
I am starting to assemble a starter pack with past and current members of our institute @iecb.bsky.social
Send me a message if you wish to be included.
go.bsky.app/L86XUk1
29.01.2025 10:30 β π 10 π 4 π¬ 0 π 0
RESEARCH ARTICLE Simulating 500 million years of evolution with a language model.
Figure 1E, shown here, displays unconditional generations from ESM3 98B (colored by sequence identity to the nearest sequence in the training set), embedded by ESM3, and projected by UMAP alongside randomly sampled sequences from UniProt (in gray). Generations are diverse, high quality, and cover the distribution of natural sequences.
An #AI model created to design proteins simulates 500 million years of protein evolution in developing a previously unknown bright fluorescent protein.
Learn more in a new Science study: https://scim.ag/40l2z3J
17.01.2025 15:07 β π 105 π 28 π¬ 2 π 4
We are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis.
#CryoEM #microsky
26.01.2025 16:55 β π 124 π 44 π¬ 2 π 0
MemBrainv2
SBGrid webinars are hosted with partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI J...
In case you missed our first webinar of 2025, it is now available. Lorenz Lamm from MUDS - Munich School for Data Science presented MemBrainv2- an end-to-end tool for the analysis of membranes in cryo-electron tomography.
https://buff.ly/4hutFwf
#SBGridwebinars #ScienceMatters
23.01.2025 18:45 β π 7 π 5 π¬ 0 π 0
https://emploi.cnrs.fr/Offres/Doctorant/UMR7255-ERICAS-004/Default.aspx?lang=EN
We have an open PhD position to work on bacterial secretion systems. Please RT, write us or apply through the CNRS job portal:
t.co/HxX23Od1oa
18.01.2025 11:57 β π 45 π 54 π¬ 1 π 1
Electron microscopy grid holder by _rouillac | Download free STL model | Printables.com
A simple design to hold flat CryoEM grid compatible with glow discharge. | Download free 3D printable STL models
π¬ Tired of dropping CryoEM grids during manipulation? Check out my 3D-printed holder! Download the STL file here: www.printables.com/model/900940.... Compatible with glow discharge systems, it makes your workflow smoother and more efficient. π‘ #CryoEM #3DPrinting #OpenScience
14.01.2025 15:06 β π 35 π 14 π¬ 2 π 0
Structural Biologist β’ Biochemist β’ Parasitologist β’ Co-host of ThePlungePodcast theplunge.org β’ Assistant Professor @ Columbia β’ Cryo electron microscopy/tomography of malarial membrane protein complexes. #teamtomo #cryoET #cryoEM #malaria cmholab.org
Group leader at University of Sheffield, photosynthesis π±βοΈ, plant physiology, biochemistry and structural biology π¬πͺπΊπ¬π§ www.Sheffield.ac.uk/photosynthesis
UCSF ChimeraX - software for visualizing biomolecules
The Collaborative Computational Project for electron cryo-microscopy (CCP-EM) supports users and developers in biological EM.
CCP-EM is based at STFC and core funded by MRC both of which are part of UKRI
https://www.ccpem.ac.uk/
I'm a Physicist and R&D Engineer. Fascinated by optimal designs, I seek to improve and invent technologies.
Homepage: amsikking.github.io
Optical imaging, interested in STEM topics.
First generation graduate from ETH ZΓΌrich
Associate Professor at UT
Southwestern Medical Center
Director of Imaging AI & Sr. Group Leader @czbiohub SF. Researcher at the meeting point of #AI, #Microscopy, and #Biology using #zebrafish as model β co-creator of @napari_imaging and #Omega. #devbio #zebrahub #deeplearning #lightsheet #Imaging #dataviz
π¬ & ποΈ & π-News & Views by Fabian Voigt - Branco Weiss Fellow in
the Engert lab at MCB @harvard.edu. Previously at UZH Zurich with Fritjof Helmchen. #mesoSPIM developer
Engineer @ EMBL Imaging Centre, EMBL Heidelberg
(he/him) Light microscopy scientist interested in developing and deploying better live-cell fluorescence microscopy technology. Tweets about microscopyπ¬, cell biology, and optics. Conflicts of interest: http://tinyurl.com/y25ctubo
Imaging scientist, light-sheet aficionado, #mesoSPIM developer, open source contributor. Building cool microscopes for cool people.
www.mesospim.org
www.github.com/nvladimus
Physicist and dad. Developing photonics tools for plasmonic chemistry and nanothermometry at UNSAM.
Drosophila brain imaging by #SnoutClub.
Photons are my own.
Super-resolution microscopy enthusiast
Postdoc at the University of Cambridge
Visiting Researcher at the British Antarctic Survey
College Research Associate at Wolfson College
https://laser.ceb.cam.ac.uk/
Developing hardware + software tools for large-scale imaging at the Allen Institute for Neural Dynamics