Amir Rahmani

My shirt is cooler than yours

Hahaha!

Yup! Over 20 mm range, and at ambient and cryogenic conditions.

The use of hexapod actuators is insane!

www.spiedigitallibrary.org/conference-p...

The telescope design is superb imo!

Reviewer #3: Aberrations are all over the place!

Protein codes and mobility together shape cellular function and disease Cells organize their biochemical activities by assembling proteins into both membrane-bound organelles and membrane-less condensates. These compartments enable specialized chemical environments that s...

www.cell.com/trends/bioch...

The laser power was set to the max by the previous users!

COS7 cells?
I haven’t imaged them on either of those microscopes though!

a person is holding an empty wallet in their hands and it is empty . ALT: a person is holding an empty wallet in their hands and it is empty .

Damn!

Fantastic night at Christ’s college for the LAG-MNG Christmas meal!
@lasergroup.bsky.social

I won’t buy a lens from you after seeing you put it upside down. 🙃

Can recommend "When Breath Becomes Air" by Paul Kalanithi.

Nature’s optics at its best! A full lunar halo lighting up the night.

Another huge advantage of miOPM is that it's gentle! A light-sheet microscope that's compatible with standard slides and multi-well plates!

-> Here we show 3D mitochondrial membrane potential in mammalian cells (GFP/RFP for mito, Cy5 for DNA). The cells move around freely!

doi.org/10.1101/2025...

Any good silicone immersion one?

Unraveling the biology and signalling potential of sparse cell antigens through single-molecule flow cytometry at University of Leeds on FindAPhD.com PhD Project - Unraveling the biology and signalling potential of sparse cell antigens through single-molecule flow cytometry at University of Leeds, listed on FindAPhD.com

PhD studentship available on using our single-molecule flow cytometry technology to detect rare proteins. Apply if you're interested in applying single-molecule techniques to improve diagnostics and to discover new routes for anti-cancer immunotherapy. www.findaphd.com/phds/project...

My guess is that you would be able to get away with an adjustable slit to tune the NA!

Always there for our group meetings!

Single-molecule friends!

The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec...
It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June:

Have a look, tell your friends, and register!

Nanosensors for real-time intracellular analytics - Nature Nanotechnology This Review provides insights into nanosensor technologies for monitoring cellular biomarkers, proposing a spatial framework to clarify their distinct advantages, challenges and performance for high-r...

www.nature.com/articles/s41...

But does it have to be H-1B visa?

Thank you! 🤓

Thrilled to see interest in this preprint! This work was a major part of my PhD, my hope is that single-molecule flow cytometry can be useful to the community in exploring new applications and discoveries.

doi.org/10.1101/2025...

I’ve never had that privilege!

I really need a keyboard blocker like this!

Huge thanks to an incredible team who made this possible 🙌 especially Aleks for his great supervision and support.

Single-molecule flow cytometry Flow cytometry (FC) is a powerful tool for high-throughput characterisation of cell populations, yet its ensemble fluorescence detection and the autofluorescence of cells impose a sensitivity limit of...

We believe smFC brings single-molecule sensitivity to scalable cell analysis.
Excited to see how this impacts biology & medicine!
Read the full story here 👇
www.biorxiv.org/content/10.1...

We applied smFC to triple-negative breast cancer (TNBC) cells:
📊 Found 30% of cells express low-abundance c-kit.
🧬 This subpopulation was invisible to standard flow cytometry, but smFC revealed it.