Amir Rahmani's Avatar

Amir Rahmani

@astormic.bsky.social

Super-resolution microscopy enthusiast Postdoc at the University of Cambridge Visiting Researcher at the British Antarctic Survey College Research Associate at Wolfson College https://laser.ceb.cam.ac.uk/

756 Followers  |  389 Following  |  205 Posts  |  Joined: 10.11.2024  |  1.5314

Latest posts by astormic.bsky.social on Bluesky

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The #MSCA results are out and the overall success rate is 9.6%. My friend with 96.8 score is in the reserve list! Interesting!

09.02.2026 14:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Which CAD software has AI tools? I mainly use OnShape and haven’t seen any AI tools to pop up!

18.01.2026 22:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

0.28

16.01.2026 13:31 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The one you have is UPlanSApo but they have a new version UPlanXApo. It’s very good!

15.01.2026 20:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

You’ve got to get the new 60X/1.20 W.

14.01.2026 22:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Haven’t taken a flight in 14 months ✈️
Won’t take one until April either, which’ll make it 17.
Just a reminder that travel choices do add up for COβ‚‚. One person skipping a flight doesn’t ground a plane, but lower demand over time does mean fewer routes and frequencies.

04.01.2026 09:12 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Crafting New Year (super-)resolutions at cold for 2026

Happy New Year everyone πŸŽ‰

01.01.2026 00:33 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Winter scene featuring a punt gliding across the River Cam, near a snow-covered arch bridge, accompanied by a 'Merry Christmas from the University of Cambridge' greeting.

Winter scene featuring a punt gliding across the River Cam, near a snow-covered arch bridge, accompanied by a 'Merry Christmas from the University of Cambridge' greeting.

Merry Christmas to all our students, staff, alumni and friends around the world πŸŽ„

πŸ“Έ Lloyd Mann

25.12.2025 08:00 β€” πŸ‘ 28    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Bored over the holidays? Give our new preprint on how #microtubule lattice alteration by taxols can regulate #RhoA #signalling via GEF-H1 a read!

Perhaps a new mechanism of action for taxol #chemotherapeutics during interphase.

www.biorxiv.org/content/10.6...

Happy holidays βœ¨πŸŽ„

24.12.2025 07:19 β€” πŸ‘ 20    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

Last project of the year: self blinking JF635 + lattice light sheet + #BigVolumeBrowser to deskew both volume and localization data (and render)
@zeiss-microscopy.bsky.social

24.12.2025 13:16 β€” πŸ‘ 17    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Nice collection of cameras!

23.12.2025 23:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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✨ Blinking #nanobodies that work for single-molecule localization πŸ”¬
Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!

22.12.2025 10:45 β€” πŸ‘ 76    πŸ” 19    πŸ’¬ 3    πŸ“Œ 2

I was incredibly fortunate in this! The ups and downs were many but all those discussions helped make sense of a few scientific questions that are still ongoing and lead to further questions.

20.12.2025 02:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution <p>Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view, typically around 1 mm. This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample, such as different brain areas. In addition, conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging <italic>in vivo</italic>. Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm, a numerical aperture of 0.5, and a working wavelength range from 400 to 1000 nm. We achieved a resolution of 0.74 ΞΌm in fluorescent beads imaging. The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system, a confocal laser scanning system, and a two-photon imaging system. This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.</p>

This is one of the examples of designing a objective lens+tube lens and I was always wondering why they don't include the scan lens in the combo design.

www.oejournal.org/oea/article/...

19.12.2025 18:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I’d say there is no obvious reason for adding telecentricity! It would make the lens bulkier (i guess) but wouldn’t change the image quality that much!

18.12.2025 20:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Great stuffs!

18.12.2025 19:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Tracking coordinated cellular dynamics directly from images -- New method paper by labmates @bgraedel.bsky.social & @macdobry.bsky.social ! Python package & @napari.org plugin, all the good stuff:

Paper: doi.org/10.1242/jcs....
Code: github.com/pertzlab/arc...
Plugin: github.com/pertzlab/arc...

18.12.2025 16:16 β€” πŸ‘ 47    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0

Cool stuff! Congrats!

15.12.2025 11:29 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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New paper out! Combining single-objective light-sheet microscopy and time-resolved SPAD array detection, we massively accelerate fluorescence lifetime imaging (FLIM) compared to confocal FLIM, making FLIM applicable to 3D specimen such as organoids and embryos.
www.nature.com/articles/s42...

15.12.2025 10:23 β€” πŸ‘ 36    πŸ” 13    πŸ’¬ 6    πŸ“Œ 2

Interesting! So one can say the GSG's role is purely translational?

13.12.2025 16:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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My shirt is cooler than yours

11.12.2025 19:06 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

Hahaha!

11.12.2025 16:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Yup! Over 20 mm range, and at ambient and cryogenic conditions.

11.12.2025 16:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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The use of hexapod actuators is insane!

www.spiedigitallibrary.org/conference-p...

11.12.2025 15:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The telescope design is superb imo!

11.12.2025 15:42 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Reviewer #3: Aberrations are all over the place!

11.12.2025 15:24 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Protein codes and mobility together shape cellular function and disease Cells organize their biochemical activities by assembling proteins into both membrane-bound organelles and membrane-less condensates. These compartments enable specialized chemical environments that s...

www.cell.com/trends/bioch...

11.12.2025 14:39 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The laser power was set to the max by the previous users!

11.12.2025 14:33 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

COS7 cells?
I haven’t imaged them on either of those microscopes though!

09.12.2025 23:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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a person is holding an empty wallet in their hands and it is empty . ALT: a person is holding an empty wallet in their hands and it is empty .

Damn!

09.12.2025 23:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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