Märkligt att Vetenskapsradions 20 min inslag om den fantastiska utvecklingen inom global hälsa, t ex minskande barnadödlighet, inte ens nämner pågående kraftiga minskningar i bistånd.
Bara slakten på USAID i fjol väntas leda till 8-20 milj dödsfall de närmaste åren, varav 4-6 milj barn.
13.02.2026 13:53 — 👍 23 🔁 17 💬 2 📌 0
When Science Funding Becomes a Lottery
or, how Europe’s funding schemes turned evaluation into ritual
'Yesterday, I learned that one of my students, who applied for a Marie Curie Fellowship, did not get it. My first reaction was to ask what could be done to improve the application in the future. Then I saw the score: above 93 points!.'
substack.com/home/post/p-...
11.02.2026 10:48 — 👍 15 🔁 7 💬 2 📌 0
Tack Nalin att du lyfter detta. Anders Österberg är min hjälte.
06.02.2026 06:37 — 👍 3 🔁 1 💬 0 📌 0
En gång för länge sen missade jag en stor ansökan med två minuter. Sen dess satsar jag på att vara klar en dag innan.
27.01.2026 14:39 — 👍 3 🔁 0 💬 1 📌 0
»Vi hade slutet på hiv-epidemin runt hörnet« - Ottar
Med förbättrad vård och läkemedel har framtiden sett ljus ut, men i år har kampen mot hiv tagit en plötslig vändning.
Den 1:a december är Världsaidsdagen. Med förbättrad vård och läkemedel har framtiden länge sett ljus ut, men i år har kampen mot hiv tagit en plötslig vändning.
– Det kommer kosta väldigt många, unga, liv, säger Anna Mia Ekström, klinisk professor i global infektionsepidemiologi med fokus på hiv.
01.12.2025 13:19 — 👍 19 🔁 17 💬 1 📌 3
Visa injustice. Listen to John Green.
23.11.2025 19:29 — 👍 4 🔁 0 💬 0 📌 0
Henry and others from all around the world demand that we stop and eradicate tuberculosis
18.11.2025 11:25 — 👍 4 🔁 0 💬 0 📌 0
And here Henry appears, recovered after many years of disease, and huge efforts by his doctors, NGOs, and in particular his mother. (She did not get a visa to come along). He is now a poet, goes to the university and enjoys life.
18.11.2025 11:21 — 👍 4 🔁 0 💬 0 📌 0
John Snow learnt about this devastating disease that kills more people than any other infectious disease in the world. He hasn’t stopped talking since then.
18.11.2025 11:10 — 👍 0 🔁 0 💬 0 📌 0
John Snow! At the Union meeting in Copenhagen. The author who wrote the book ”Everything is tuberculosis” that was the number one on The New York Times list of non-fiction books for many weeks. How he met the young boy Henry with multiresistant tuberculosis in a hospital in Sierra Leone.
18.11.2025 11:06 — 👍 0 🔁 0 💬 1 📌 0
Well done!
17.11.2025 21:36 — 👍 0 🔁 0 💬 0 📌 0
Welcome!
11.10.2025 00:15 — 👍 1 🔁 1 💬 0 📌 0
Welcome!
05.10.2025 20:52 — 👍 1 🔁 0 💬 0 📌 0
I agree. It helped me sort my thoughts.
01.10.2025 08:43 — 👍 1 🔁 0 💬 0 📌 0
Paired single-cell and spatial transcriptional profiling reveals a central osteopontin macrophage response mediating tuberculous granuloma formation - Single Cell Portal
Granulomas are classic manifestations of tuberculosis pathogenesis. They result from an ensemble of immune responses to Mycobacterium tuberculosis infection, but the identities, arrangement, cellular interactions, and regulation of the cells that comprise them have thus far been incompletely understood. To better understand the composition of granulomas, we conducted spatial and single-cell RNA sequencing of granulomas in biopsy specimens from patients with tuberculosis. We found that granulomas consist of concentric transcriptional laminae surrounding areas of central necrosis. We identified distinct populations of granuloma-associated stromal cells, fibroblasts, lymphocytes, mast cells, dendritic cells, neutrophils, and macrophages. Furthermore, gene expression among these cell populations differed by location within granulomas. We used inferential analysis to predict dominant granuloma cell-cell interactions, the activity of major signaling pathways, and transcription factor activities. Using spatial deconvolution, we mapped a conserved pattern of cellular organization dominated by macrophages rich in SPP1/osteopontin expression. Trajectory analysis of macrophage subtypes mapped their differentiation and supported the importance of SPP1 to granuloma macrophage polarization. Using the Mycobacterium marinum-zebrafish model, we found that mycobacterial infection induces spp1 expression in macrophages and that spp1 ablation results in granuloma formation defects and reduced survival in adult animals. Cumulatively, we have identified a dominant macrophage granuloma population as well as its central regulatory gene in human samples and confirmed the importance of spp1 to granuloma biology in vivo.
You can now explore the mRNA expression of your favorite TB gene of interest in our recently published human pulmonary M.tb granuloma single-cell dataset at the Broad Single Cell PORTAL!
@broadinstitute.org
@wallacewly.bsky.social
singlecell.broadinstitute.org/single_cell/...
04.09.2025 13:38 — 👍 18 🔁 6 💬 1 📌 1
Jösses
28.09.2025 07:36 — 👍 5 🔁 1 💬 3 📌 0
”Förbannelsen” är en essä av högsta klass
RECENSION En av de klokaste samtidsdiagnoserna på 2000-talet
Karin Petterssons ”Förbannelsen” är en essä av högsta klass, skriver gästrecensent Stefan Jonsson: www.aftonbladet.se/kultur/bokre...
03.09.2025 05:20 — 👍 16 🔁 7 💬 0 📌 3
Grattis till en viktig bok, och välförtjänt recension!
02.09.2025 13:46 — 👍 1 🔁 0 💬 1 📌 0
Rimlig/ legal rätt att (för)neka?
20.08.2025 13:40 — 👍 0 🔁 0 💬 0 📌 0
Fast väldigt länge sen. Kanske dags att börja om. När jag läste hans första bok (The Search) var jag inte medveten om hur personlig den var, att han lämnade forskningen på grund av en artikel i Nature som visade sig vara inkorrekt.
12.08.2025 07:04 — 👍 1 🔁 0 💬 1 📌 0
Ja varför har jag inte läst honom på länge?
11.08.2025 23:32 — 👍 1 🔁 0 💬 1 📌 0
Please let me introduce Dr. Farida Ouedraogo, an African STARS Fellow of the advancing translational training (ATT) programme. You will inspire many others in Africa to become both clinician scientists and innovators! #YoungAfricaWorks #AfricanSTARSfellows
07.08.2025 06:24 — 👍 9 🔁 2 💬 0 📌 0
Jag med, fast i Word
02.08.2025 14:30 — 👍 1 🔁 0 💬 0 📌 0
En grej med långvarig undernäring och svält är att det förstör kroppen på små barn och skapar livslånga men även för dem som överlever.
24.07.2025 08:53 — 👍 44 🔁 16 💬 1 📌 1
Congratulations @yichnliu.bsky.social! This is a great moment to launch your #glycotime tools company, we need access to more lectins for glycoprofiling and functional glycomics, and also future therapeutic applications 👏
14.07.2025 15:19 — 👍 14 🔁 3 💬 0 📌 0
Så intressant. Tycker att det snarare borde uppfattas som mindre akademiskt. Och användbart.
14.07.2025 09:06 — 👍 0 🔁 0 💬 0 📌 0
Senior Digital Editor for MeidasTouch.com
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Internet Hooligan...
Historian of technology & dad joke aficionado who lived w/a great little gray rabbit until recently (RIP).
I won’t share AI generated content, except to critique it.
In person I’ll be wearing a KN95. If you care about me put one on too.
www.marhicks.com
Fighting every day to deliver a city that working New Yorkers can actually afford. Mayor of New York City.
Infectious diseases MD & researcher focusing on tuberculosis
#IDsky #MedSky
University of Alberta 🇨🇦
#womenlifefreedom
Infectious disease epidemiologist | Assistant Professor in #TB modelling @lshtm.bsky.social | Mama to 👦👦👦🐶
🏴 Cytokines Parasites
Professor and Chair, Department of Microbiology, University of Chicago. Study the pathogenesis of tuberculosis, and other mycobacterial infections. Opinions my own.
Advokat som värnar integritet och rättssäkerhet. Författare inom förenings- och förvaltningsrätt. Driver Sveriges första advokatbyrå med kollektivavtal. Vaktar inte tungan. Privata inlägg.
Duke University | Tobin Lab Postdoc | PharmD, PhD
Translational Scientist interested in Cell Biology — Genetics — Microbiology — Pharmacy — Immunology — Zebrafish — Tuberculosis
Opinions are my own & don't represent those of my employer.
Epidemiology, infection
https://profiles.ucl.ac.uk/37299-tom-yates/about
Infectious diseases & genomics. Immunologist in (voluntary) exile. Minimal sarcasm. Fierce HOA (Hater of Acronyms). Personal account - opinions expressed are my own and not those of my employer.
Mucosal Immunology lab in Montreal studying helminths, intestinal physiology and the microbiome: www.king-lab.com 🏳️🌈
Author (The Fault in Our Stars, The Anthropocene Reviewed, etc.)
YouTuber (vlogbrothers, Crash Course, etc.)
Football Fan (co-owner of AFC Wimbledon, longtime Liverpool fan)
Opposed to Tuberculosis
Infectious diseases and their global story
American in Paris, formerly a Swede in New York.
I write for The Guardian, Washington Post & Dagens Nyheter.
New book on soft power Wildfire/Hachette 2026.
https://linktr.ee/martingelin
Gillar folk, solidaritet, omfördelningspolitik, sociala skyddsnät, forskning och framsteg.
staff writer at The Atlantic, covering science. former microbiologist / forever cat enthusiast. (she/her) SIGNAL: @katherinejwu.12
Virologist, comparative virus/host interactions of HIV, Flu, Ebola and SARS CoV-2
Unashamed fan of loud shouty music. Not left-wing, not right-wing, not too fond of historical or present day fascists.
