Daniel Alber

Have you tried a workstation with more RAM and VRAM? We were getting similar issues with files corrupting which were resolved with more memory. Imaris will use more RAM than the raw file size. Unfortunately, no way I know of to salvage the corrupted files.

Now #published in Phys. Rev. Lett. as an Editors' Suggestion: "Mechanics of poking a cyst" - the first paper from the PhD work of @zhaoshh.bsky.social.

journals.aps.org/prl/abstract...

@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...

How many cells do you need to establish PCP? The magic number is 3! Beautiful work by Lena Basta in Danelle Devenport's lab. Happy to have contributed. www.science.org/doi/10.1126/...

How do cells migrate without substrate, e.g. in embryogenesis, when extra-cellular matrix has not yet formed?

Check out our paper in @cp-cellreports.bsky.social on zebrafish lateral mesendoderm migration, led by @stetavano.bsky.social @heisenbergcplab.bsky.social!

www.cell.com/cell-reports...

A tension-induced morphological transition shapes the avian extra-embryonic territory Michaut et al. show that the tension produced during epiboly elastically stretches the extra-embryonic (EE) territory, while the embryo proper (EP) remains unaffected. Although the whole epiblast (EP ...

I am delighted to share with you my first postdoc paper, which has now been published in @currentbiology.bsky.social!
www.cell.com/current-biol...
Thanks to everyone who contributed: A. Chamolly, @aurelienvilledieu.bsky.social, F. Corson and @jeromegros.bsky.

New #preprint: "Euler buckling on curved surfaces" arxiv.org/abs/2503.04303

@zhaoshh.bsky.social and I ask the question that Euler left open: How does an elastic line buckle within a (general) curved surface?

@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

New #preprint: "A model for boundary-driven tissue morphogenesis" arxiv.org/abs/2503.03688.

A great collaboration with @danielalber.bsky.social @zhaoshh.bsky.social, Alexandre Jacinto, Eric Wieschaus, Stas Shvartsman.

@flatironinstitute.org @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

Developmental systems have regions that deform actively or passively from their active neighbors. We use a ring of tissue as a model to investigate this boundary-driven morphogenesis in its biological context, learning something about gastrulation and possibly blastopore geometries in the process!

A duo of preprints on the dynamics of the first cell fate decision in mouse by Madeleine Chalifoux (first grad student in the lab!) and Maria Avdeeva (Flatiron).

We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.