Yoona Kim

Thanks AEpiA! I’m thrilled to be part of the ECR representatives and to contribute to this great community.

We also welcome our new ECR representatives joining Rachel Woodhouse (ACT), Trung Nguyen (WA), and Braydon Meyer (NSW):
Danya Challis (SA)
Yoona Kim (VIC) @yoonakim.bsky.social

1/ H3K27me3 mimicry has repeatedly emerged through evolution, but what's the physiological relevance?

We show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2 in vivo and restrict the spread of Polycomb domains.
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www.biorxiv.org/content/10.1...

Dynamic PRC1–CBX8 stabilizes a porous structure of chromatin condensates - Nature Structural & Molecular Biology Here the authors show that a gene-inactivating protein complex packs inactive genes into a dynamic and accessible structure. The study challenges the traditional views that restricted accessibility an...

We used cryoET and biophysical approaches in vitro together with molecular biology in differentiated cells to show that chromatin compacted by PRC1-CBX8 is porous and accessible while PRC1 is dynamic in it. 🧪🧬 #cryoET #Epigenetics #Polycomb www.nature.com/articles/s41...

1/ Baculovirus vector building without PCR!

We updated our MoClo Baculo preprint: www.biorxiv.org/content/10.1...
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Plasmids are available on @addgene.bsky.social, we are working on making them a kit.

Putting together packs of transcription and Chromatin people - Nominate others to add! go.bsky.app/5zgpZfg

With some help from @raduzabet.bsky.social, I've created a starter pack of researchers working on #Epigenetics, Chromatin and Gene Regulation who are active on here:
go.bsky.app/TKp9YAn
I've likely missed many people so let me know if you want to be added. Similarly if you would like to be removed.