My top 10 ID papers for 2025. Full citations and descriptions available at clarityinitiative.org/hot-takes
Also see/hear our Communicable podcast episode on this at communicable.transistor.fm/episodes/com...
What were your top 10? Any thoughts about what I missed welcome!
#IDSky #Top10papers
05.02.2026 23:28 β π 28 π 6 π¬ 1 π 1
Medical research spending has a positive return on investment; for every $ invested there's an estimated $4 return. Beyond economics, delays hold up medical innovations
Australians deserve better
If you agree, please sign the petition to let #auspol leaders know why medical research matters
#NHMRC
28.01.2026 02:10 β π 10 π 3 π¬ 0 π 0
π£ New #Communicable drops Mon 26 Jan! In our last episode, we brought you some favorite #clinmicro papers of 2025. We continue this thread in our next episode with top ID papers of 2025, picked by our editors, Josh Davis & Emily McDonald and guest, Steven Tong. β Tune in MondayποΈ
#IDSky
22.01.2026 10:45 β π 8 π 5 π¬ 0 π 1
C gattii?
22.01.2026 07:37 β π 1 π 0 π¬ 1 π 0
Great to see this paper and editorial! Convincing for HIV and C neoformans.
Where is the field regarding non HIV patients? And also C gattii meningitis? Are there trials being conducted in these populations?
22.01.2026 07:35 β π 2 π 0 π¬ 1 π 0
We're going to randomise patients in SNAP to: 1) clopidogrel vs no clopidogrel (CLOPIDO SNAP #1) and; 2) aspirin vs clopidogrel for those already on aspirin (CLOPIDO SNAP #2).
20.01.2026 04:38 β π 2 π 1 π¬ 0 π 0
πDrug Hypesensitivity Symposium 2026 - #DHS2026
Registrations are now open for our amazing 3-day #drugallergy & #antibioticallergy program in Melbourne 23-25th October 2026.
Stellar internationalπspeaker lineup. @allergy-eaaci.bsky.social @thedohertyinst.bsky.social
β‘οΈhttps://dhs2026.org/
19.01.2026 08:40 β π 1 π 1 π¬ 0 π 0
Agree. It's a short, well researched, and strangely moving book. Well worth reading.
18.01.2026 18:45 β π 1 π 1 π¬ 0 π 0
Everything Is Tuberculosis: The History and Persistenceβ¦
Tuberculosis has been entwined with humanity for millenβ¦
I see patients with TB every week. I can access modern diagnostics and treatments. Reading this book reminded me that is not the case in much of the world.
TB kills 1.25 million per year.
A disease of injustice.
Everything Is Tuberculosis: John Green www.goodreads.com/book/show/22...
18.01.2026 09:58 β π 16 π 6 π¬ 1 π 0
We are genotyping and phenotyping as many of the isolates as we can get hold of (will be most). So the analysis of blaZ and cefazolin inoculum effect will follow once done. Can't wait to see what this shows!
Altogether there were 1341 participants in SNAP, so much larger than CloCeBa.
18.01.2026 04:45 β π 8 π 1 π¬ 0 π 0
Saw the post on X also - but I've decided today to deactivate my X account!
Agree with others that the numbers are too small in CloCeBa to draw strong conclusions.
Across the board in SNAP, cefazolin was better (15% mortality vs 17%). Similar in the 100 odd patients with endocarditis.
18.01.2026 04:45 β π 6 π 0 π¬ 1 π 0
Research Officer
The OpportunityHere at The Kids our vision is simple; Happy, Healthy Kids!The Infectious Diseases Epidemiology Team is dedicated to
reducing the burd...
Exciting news - there's a spot open in the #IDepi team at @thekidsau.bsky.social !
Prof Chris Blyth is looking for a Research Officer to work on influenza research
1-year initial contract based in Perth
Slight bias (my team/boss) but it's a fantastic opportunity!
#EpiSky #AcademicSky #AusAcademia
15.01.2026 00:44 β π 3 π 2 π¬ 0 π 0
Now I'll have a look at how Covid-19 deaths have changed over time.
See the quoted thread for discussion of how cases, emergency department visits, and hospitalizations have changed over time.
1/
13.01.2026 06:55 β π 10 π 3 π¬ 2 π 2
Ouliβs a clinician who developed incredible bioinformatics and coding skills. Plus the smarts to use those skills to communicate ideas
12.01.2026 20:34 β π 2 π 0 π¬ 0 π 0
Pretty cool that Robin Patel picks Ouli Xie's @lancetmicrobe.bsky.social paper on SDSE and S pyogenes as one of her top 3 clinical microbiology papers for 2025! As expected, Robin does a great job explaining the paper.
www.thelancet.com/journals/lan...
@onisillos.bsky.social
12.01.2026 03:04 β π 15 π 7 π¬ 2 π 0
The other thing that hasn't been well measured is secondary GAS infections (that are not 'invasive'). Possible that some of these are prevented.
10.01.2026 11:21 β π 1 π 0 π¬ 0 π 0
We selectively do this in Australia. Always tricky with how rare the outcome is: βThe secondary attack rate among household contacts was 0.219% (7 individuals) before and 0.047% (7 individuals) afterβ.
We are doing a RCT, but the primary outcome is throat recovery of GAS, not clinical infection
09.01.2026 23:04 β π 6 π 0 π¬ 1 π 0
Intrigued. Canβt wait to listen!
08.01.2026 10:12 β π 1 π 0 π¬ 0 π 0
How Do We Win? The GAME CHANGER Trial
Erin K. McCreary, PharmD (1), Ahmad Mourad, MD MHS (2, 3)
The 3rd and 4th commentaries on recent ID trials are up on the CLARITY website (we aim to publish in depth reviews of important ID stuies).
This time looking at the GAMECHANGER trial:
clarityinitiative.org/commentaries...
@erinmccreary.bsky.social with Ahmad Mourad
@gurujosh.bsky.social
#IDSky
01.01.2026 23:50 β π 12 π 5 π¬ 0 π 0
Collage titled "Most Viewed JAMA 2025," featuring medical diagrams and study results: lung scans, iron absorption, DNA repair, biofilm formation, coffee consumption/abstinence study, and organ system treatments.
The numbers are in.
This year's most popular JAMA content spans a range of topics, from coffee and #AFib to #osteoporosis to #SepticShock. What was your favorite article in 2025βand did other readers agree?
π ja.ma/49dIcKr
28.12.2025 16:00 β π 4 π 2 π¬ 0 π 0
Nice to see #MethodologyMonday again!
15.12.2025 08:47 β π 2 π 0 π¬ 0 π 0
Congrats!
08.12.2025 08:26 β π 0 π 0 π¬ 0 π 0
Non pay walled link: authors.elsevier.com/a/1mCdH3AjoX...
07.12.2025 03:32 β π 6 π 2 π¬ 1 π 1
Navigating the Challenges in Staphylococcus aureus Bloodstream Infection: A Practical Guide to Management
New article about how to manage Staphylococcus aureus bacteremia. Led by Hadar Mudrik-Zohar. Includes @seanong.bsky.social @drtoddlee.bsky.social
#IDSky #SNAP_trial
www.sciencedirect.com/science/arti...
04.12.2025 02:53 β π 14 π 6 π¬ 0 π 0
A reflection on decades of work to improve skin health in remote Australian communities: www.nhmrc.gov.au/about-us/res...
@ashabowen.bsky.social @nhmrc.bsky.social @thedohertyinst.bsky.social
04.12.2025 02:51 β π 2 π 0 π¬ 0 π 1
Clarity Initiative
Clinical Literature Appraisal and Research education in InfecTious diseases
A group of ID clinical researchers passionate about clinical research and evidence appraisal has just launched the CLARITY initiative (clarityinitiative.org), which aims to improve the generation and interpretation of evidence in ID and Microbiology.
30.11.2025 23:39 β π 17 π 11 π¬ 1 π 0
Orthopedic infections doc.
Neonatologist and Professor of Newborn Medicine, Mercy Hospital for Women and The University of Melbourne, Melbourne, Australia | Co-PI of @platipus.bsky.social
Perinatal adaptive platform trial to improve outcomes of preterm birth
Website: platipustrial.org
Emergency physician and statistician; Bayesian adaptive and platform trial clinical trial design and implementation; Senior Statistical Editor at @jama.com.
ID doc & Antibiotic Steward β’
β’ Clinical trials and #FOAMed believer β’
Now on @shorten2trial.bsky.social
#AMSsky #IDSky #AMR
Hospital Virgen del RocΓo β’ Seville, Spain πͺπΈ
ID physician in Melbourne, Australia.
Clinical Microbiologist. Women's infection health, urology, antimicrobial stewardship, diagnostics.
Associate Editor @ CMI Communications.
The Peter Doherty Institute for Infection and Immunity is a joint-venture between The University of Melbourne and The Royal Melbourne Hospital. Research includes #HIV, #hepatitis, #malaria, #influenza #COVID19 & more.
www.doherty.edu.au
WikiGuidelines is a collaborative effort to transform how clinical guidelines are constructed. We seek to incorporate humility of uncertainty into guidelines.
wikiguidelines.org
The Lancet Infectious Diseases is the leading clinical infectious diseases journal for peer-reviewed research and review, comment, and news.
π https://www.thelancet.com/journals/laninf/home
The Lancet Microbe is an #OpenAccess journal publishing innovative and practice-changing research and opinion in clinical #microbiology
π thelancet.com/journals/lanmic/home
Professor of Paediatric Infection, University of Liverpool. Sepsis, antimicrobial stewardship, biomarker-guided trials in infection, paediatric early warning scores, health inequalities. Personal views.
ID PharmD π
BCPS, BCIDP, FCCP, FIDSA, FIDP, FMSHP π
Alllllll the letters π«£
OPAT, NTM, outpatient ID, double spacing, friendship bracelets & Taylor Swift π«Ά
ID clinician scientist. AHD, TB, diagnostics. Runner, father, husband
Prof @cambridgebiosci.bsky.social Connecting pathogen evolution with public health outcomes. #Shigella and #AMR enthusiast. Views own. http://gen.cam.ac.uk/baker-group also www.pdu.gen.cam.ac.uk also @pducambridge.bsky.social
Infectious Diseases MD at NYU
#IDSky
Formerly fellow at WCM
Antibiotic Steward | Amateur Classicist
Pronomina: is/eius/ei/eum/eo
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