Big congrats to the entire Kaessmann lab for this spectacular achievement and beautiful insights. It was a great honour to contribute to this study and to host Ioannis in our lab, an absolutely brilliant scientist. Evolution of genomic enhancers controlling neuronal cell types is just too cool..
29.01.2026 19:36 β π 17 π 1 π¬ 2 π 0
We are thrilled that our study on the evolution of gene regulation in mammalian cerebellum development β led by @ioansarr.bsky.social, @marisepp.bsky.social and @tyamadat.bsky.social, in collaboration with @steinaerts.bsky.social β is now out in @ScienceMagazine! www.science.org/doi/10.1126/...
29.01.2026 19:23 β π 87 π 35 π¬ 3 π 6
This is figure 1, which shows AlphaGenome model architecture, training regimes and comprehensive evaluation performance.
A paper in Nature presents AlphaGenome, a deep learning model that can predict the function of long DNA sequences, up to one million base pairs. The tool can predict how DNA sequence variations affect different biological processes. go.nature.com/4t5JQa7 𧬠π§ͺ
28.01.2026 23:29 β π 36 π 21 π¬ 0 π 0
𧬠Only one month until the 2nd meeting on early embryogenesis & epigenetics. #Embryo2026
Barbara Treutlein (@ethz.ch) will speak about her work reconstructing human brain development with organoids and single-cell technologies!
More information: www.molgen.mpg.de/embryo2026
13.01.2026 14:13 β π 7 π 4 π¬ 0 π 0
An expanded registry of candidate cis-regulatory elements - Nature
The existing ENCODE registry of candidate human and mouse cis-regulatory elements is expanded with the addition of new ENCODE data, integrating new functional data as well as new cell and tissue types...
Our paper on the newest version of the Registry of candidate cis-Regulatory Elements (cCREs) is out π§¬
Huge thanks to the many collaborators, experimentalists, analysts and software developers who made this work possible β truly a team effort!
A "meme-torial" of the science is coming soon π
07.01.2026 18:47 β π 56 π 31 π¬ 1 π 2
Now out: The new ENCODE registry of candidate cis-regulatory elements (π/πΆ)
Major consortium effort, led by @moorejille.bsky.social - stay tuned for her "meme-torial"
www.nature.com/articles/s41...
@berkeleylab.lbl.gov @biosci.lbl.gov
07.01.2026 21:44 β π 27 π 10 π¬ 1 π 0
Excited to share our final accepted version of the CiFi method out today: www.nature.com/articles/s41...
08.12.2025 17:55 β π 51 π 16 π¬ 1 π 1
If you are planning to attend the Mutational Scanning Symposium (and companion workshops!) we recommend that you register as soon as possible to secure your spot!
βΉοΈ www.mss2026.org
Keynotes! @mehurles.bsky.social @maitreya.bsky.social
#VariantEffect26 #Symposium #Workshop #RegisterNow
24.11.2025 14:31 β π 5 π 2 π¬ 0 π 1
"We thank the reviewers for their helpful suggestions"
23.11.2025 11:19 β π 185 π 18 π¬ 2 π 1
IMPRS-BAC #gradschool: Our new groupleader @sedonamurphy.bsky.social has an open PhD project in her lab. Topic: Spatial feedback between epigenetic regulation and chromatin regulation. Apply by Jan 7, 2026!
π www.molgen.mpg.de/5091778/Murp...
18.11.2025 16:05 β π 19 π 11 π¬ 0 π 0
Ten days left to apply to be a @crick.ac.uk Early Career Group Leader
Closing date 27th November
www.crick.ac.uk/careers-stud...
17.11.2025 11:55 β π 60 π 58 π¬ 0 π 0
π’ Speaker showcase for our 2nd Meeting #Embryo2026 π§¬Vincent Pasque @pasquelab.bsky.social from @kuleuvenuniversity.bsky.social will speak about his work on modelling early human embryogenesis with naΓ―ve pluripotent stem cells.
More informationπ
www.molgen.mpg.de/embryo2026
14.11.2025 14:59 β π 10 π 3 π¬ 0 π 0
We were very happy to welcome this amazing group of early-career researchers as part of the @Falling Walls Science Summit in Berlin! Special thanks to @annaamonaco.bsky.social (Mundlos Lab) and @matthewkraushar.bsky.social for hosting the group and providing an in-depth tour of their labs!
11.11.2025 10:06 β π 9 π 3 π¬ 0 π 0
Thrilled to start my Group Leader adventure with these and other great scientists!
06.11.2025 20:11 β π 60 π 11 π¬ 5 π 0
Three new research groups joining the MPIMG
We are excited to welcome @fueyoraquel.bsky.social, @sedonamurphy.bsky.social, and @jmstein.bsky.social as new group leaders at our institute!
Read more about their work:
--> www.molgen.mpg.de/2025-10-31-n...
All three are recruiting in the IMPRS PhD Call!
--> www.molgen.mpg.de/IMPRSPhDproj...
06.11.2025 16:00 β π 41 π 10 π¬ 0 π 3
π§¬π’ We look forward to welcoming Jacob Hanna from the Weizmann Institute of Science as part of our speaker lineup for the #Embryo2026 meeting!
More information π
www.molgen.mpg.de/embryo2026
05.11.2025 12:31 β π 5 π 2 π¬ 0 π 0
ποΈAbstract Deadline Extended
to December 1st, 2025!
#VariantEffect26
βΉοΈhttps://www.mss2026.org
03.11.2025 14:30 β π 5 π 4 π¬ 0 π 0
The IMPRS-BAC call is open until January! Interested in applying to the graduate school? Here are ten tips for a successfull application! β¬
Check out our projects and apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
#IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
28.10.2025 10:51 β π 4 π 4 π¬ 0 π 0
SharePic for the contribution of Eileen Furlong from EMBL for the 2nd Meeting on Early embryogenesis & epigenetics organized by the Max Planck Institute for Molecular Genetics in Berlin with support by the Weizmann Institute for Science. The SharePic features the portrait of Eileen and the title of her contritbution "Genome regulation during embryogenesis: Going loopy about enhancer regulation".
π’𧬠Next in the speaker line-up for #Embryo2026 is @eileen-furlong.bsky.social from @embl.org who will present her research on
"Genome regulation during embryogenesis: Going loopy about enhancer regulation"
Register until Oct 31! π
www.molgen.mpg.de/embryo2026
Supported by the Weizmann Institute
24.10.2025 11:13 β π 12 π 5 π¬ 0 π 0
Enhancer activation from transposable elements in extrachromosomal DNA - Nature Cell Biology
Kraft, Murphy, Jones et al. identify extrachromosomal DNA (ecDNA)-interacting elements (EIEs) enriched for transposable elements within ecDNA in colorectal cancer cells. They show that EIE 14 integrat...
Delighted to share our new study in @natcellbio.nature.com showing that the unique epigenetic landscape of ecDNA can enable the oncogenic enhancer activation of transposable elements! This was a great collaboration with @katerinakraft.bsky.social and @sedonamurphy.bsky.social. tinyurl.com/mwfbu4w4
21.10.2025 14:42 β π 9 π 2 π¬ 1 π 1
π’Speaker showcase for our 2nd Meeting #Embryo2026 π§¬
@jamesbriscoe.bsky.social from @crick.ac.uk will speak on
The Dynamics of Neural Tube Formation
More information on www.molgen.mpg.de/embryo2026
17.10.2025 08:22 β π 9 π 2 π¬ 0 π 0
Our November 2025 issue is now live: go.nature.com/4hlXnVx
Topics include: the impact of structural variation on the 3D genome in disease; single-cell DNA sequencing of somatic mutations; the role of transcription compartments in gene regulation; synonymous mutations and their consequences
15.10.2025 11:54 β π 6 π 2 π¬ 1 π 0
Super excited about first Shendure/Baker Lab collaboration & preprint on a multiplex sequencing-based strategy for screening de novo proteome editors in mammalian cells. Kudos to the brilliant Chase Suiter (not here) & @greenahn.bsky.social on the work! Preprint here:
www.biorxiv.org/content/10.1...
14.10.2025 18:44 β π 97 π 33 π¬ 0 π 0
Hello Boston! The lab is delighted to be at #ASHG25π§¬
Check out our talks over the next few days - all unpublished stories.
Kicking things off is @michaelherger.bsky.social presenting "Saturation mutagenesis of 37 human splicing factor genes with pooled prime editing". Today @2pm, Rm205abc
Also π
15.10.2025 14:42 β π 15 π 5 π¬ 1 π 0
π§¬Founded in 1948, the American Society of Human Genetics (ASHG) is the primary professional membership organization for #humangenetics specialists worldwide.
www.ashg.org
Assistant Prof. @ UMass Chan: studying gene regulation with multi-omic data and comp methods
www.moore-lab.org
enthusiast of transposable elements, genetic conflicts, small RNAs, Drosophila, and funky germline biology
running a lab at IMBA, Vienna BioCenter
https://www.oeaw.ac.at/imba/research/julius-brennecke
Biologist. Chromosomes | dinoflagellates | birds. Happy in academia! Umass Chan Medical School, HHMI
http://www.dekkerlab.org
How do molecules and cells create life? Follow @biozentrum.unibas.ch for the latest news on research & education.
Postdoctoral researcher at @radaiglesiaslab.bsky.social | Developmental genomics | Prelighter (The Company of Biologists) | Artistic & Creative | Passionate about visual storytelling and design
Stem cell and developmental biologist, Professor @ University of Leuven, Belgium. #Pluripotency #Epigenetics
Group leader at Institut Jacques Monod. When I say "epigenetics" what I really mean is "DNA methylation".
www.maximgreenberglab.com
Group leader at the Max Planck Institute for Molecular Genetics π¬π§¬π§ͺπ§«ππ€. Former UCSF, MPI Freiburg, Bilkent Uni & METU. Diversity is power.
https://www.molgen.mpg.de/Genome-Regulation/Bulut-Karslioglu-lab
Director of Program Operations (Variant Effects Portfolio) CMAP, CAVA and the Atlas of Variant Effects Alliance | she/her π³οΈβπ
https://fowlerlab.gs.washington.edu/people
https://brotmanbaty.org/research/atlas-of-variant-effects
Developmental Biologist working at the Francis Crick Institute. Neural tube, morphogens, and gene regulatory networks. Editor-in-chief, Development.
London Β· briscoelab.org
Doudna Lab at UC Berkeley, Innovative Genomics Institute founder, CRISPR co-inventor and Nobel laureate innovativegenomics.org/
Senior editor @science.org. Molecular biology, #DNA, #RNA, #gene regulation, #epigenetics, nuclear biology, #chromatin biology, 3D #genome, #synbio, #CRISPR and gene editing, other bacterial immune systems, and #AI in all these
Group Leader at Max Planck Institute of Molecular Genetics
https://www.molgen.mpg.de/fueyo-lab
Gene regulation | Transposons | Human embryo development
HFSP promotes and supports international, cutting-edge, and interdisciplinary research focused on the life sciences. This page shows the latest news from HFSP and other items of interest to the scientific community.
Palestinian Stem Cell Scientist. Palestinian and LQBTQ+ rights advocate. #Arab&BlackLivesMatter #EndOccupation #FreePalestine #PeaceNOW #CeasefireNOW #BringThemHomeNow! Personal account.
Evodevo biologist, juggling mum, retired dive instructor.
Scientist in transit. Meet me @College-de-France ParisπͺπΊ or @Arollaπ¨π#InHoxWeTrust #GesamtNaturWerk. Et Ce Fut Tout.
Chromatin and cryoEM afficionada. Still a fan of crystallography. Avid Colorado hiker. Will call out ugly nucleosome cartoons. Come for the science, stay for the mountain pictures and snark. Opinions and snark are my own.
Group leader @Bar Ilan University. Interested in sex determination, stem cells and 3D genome organisation. Head of the BIU transgenic unit. ERC StG 2022. Mom of 4.
