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Joe Beckwith

@jsbeckwith.bsky.social

Spectroscopist, microscopist, pessimist. SRA in the Cambridge Chemistry Department. Science and/or nonsense. Occasionally a post about personal matters, instantly regretted. he/him | πŸ³οΈβ€πŸŒˆ

517 Followers  |  280 Following  |  29 Posts  |  Joined: 21.09.2023  |  1.8935

Latest posts by jsbeckwith.bsky.social on Bluesky

Presumably you could become motion sick just from walking, at that rate

04.12.2025 21:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Sorry how is roller coasters even close to most surprising

04.12.2025 21:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Your Party's new slogan "It's Your Party, so cry if you want to"

29.11.2025 20:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

rich dudes got freakier after butlers fell out of fashion, like say what you will about having domestic servants but clearly it was some sort of moderating force on old rich dudes having a fancy man follow you around saying shit like "oh dear sir, that wouldn't be very becoming"

29.11.2025 06:43 β€” πŸ‘ 7328    πŸ” 1132    πŸ’¬ 90    πŸ“Œ 139

Thrilled to see our recent preprint on tipping points in neurodegeneration highlighted on Alzforum!
Read it here: www.alzforum.org/news/researc.... Many thanks to Jessica Shugart for the engaging coverage, and to everyone involved in this exciting project at the @ukdri.ac.uk and elsewhere!

17.11.2025 22:44 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Large-scale visualization of Ξ±-synuclein oligomers in Parkinson’s disease brain tissue - Nature Biomedical Engineering An optical detection and analysis platform quantifies aggregate density, distribution and size in fluorescently labelled post-mortem human brain tissue.

www.nature.com/articles/s41...

It's out at last! Work that I was totally privileged to be a part of led by @becs-andrews.bsky.social, with @jcbreiter.bsky.social @stevethechemist.bsky.social and funded by @asapresearch.parkinsonsroadmap.org

01.10.2025 16:35 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026" March 15-20 2026, Les Houches, France

Please share: The application for Les Houches is open (until Oct 31)

fluorescenceleshouches.wordpress.com

*This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!*

PS: no fees this year, you just need to get there, that's all!

12.09.2025 09:03 β€” πŸ‘ 26    πŸ” 22    πŸ’¬ 0    πŸ“Œ 1

I am finding the fact that "is it acceptable and proportional to call for trans women to be assaulted in public" is now a subject of public debate in the UK really very upsetting.

03.09.2025 14:21 β€” πŸ‘ 381    πŸ” 95    πŸ’¬ 5    πŸ“Œ 1
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease Parkinson's disease (PD) is characterised by insoluble Ξ±-synuclein (Ξ±Syn) aggregates in Lewy bodies (LBs) within the substantia nigra, with cortical pathology appearing as the disease progresses. Late...

Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease.

www.biorxiv.org/content/10.1...

Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi

01.09.2025 09:14 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1
Postdoctoral Research Associate in Single-Molecule Imaging and Super-Resolution Microscopy (Fixed Term) | Yusuf Hamied Department of Chemistry Fixed-term: The funds for this post are available for 2 years in the first instance. Fixed-term: The funds for this post are available for 2 years in the first instance. Applications are invited for a...

Single-Molecule Friends! Just 10 more days to apply for an exciting joint postdoc with @KlenermanLab, feel free to research out www.ch.cam.ac.uk/job/52425

01.09.2025 08:22 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1

28.08.2025 16:15 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Lovely bit of business this wordplay

19.08.2025 20:43 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Postdoctoral Research Associate in Single-Molecule Imaging and Super-Resolution Microscopy (Fixed Term) Fixed-term: The funds for this post are available for 2 years in the first instance. Fixed-term: The funds for this post are available for 2 years in the first instance. Applications are invited for

Build microscopes, solve immunology (kinda)... come and work with us! We have an exciting collaborative postdoc position in the group. www.cam.ac.uk/jobs/postdoc...

14.08.2025 10:41 β€” πŸ‘ 0    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Cool work from a cool lab!

12.08.2025 19:36 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...

09.07.2025 17:56 β€” πŸ‘ 13    πŸ” 14    πŸ’¬ 1    πŸ“Œ 0
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Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).

Please apply and/or repost!

jobs.unige.ch/www/wd_porta...

07.07.2025 14:05 β€” πŸ‘ 57    πŸ” 50    πŸ’¬ 0    πŸ“Œ 1

Why have I done this ridiculous pose

27.06.2025 09:10 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited to share some recent work tracking the 3D movement of individual molecules inside the organelles of living cells (πŸ’‘+ 🦠 + βš½οΈπŸ’¨) with the best team @joechambers.bsky.social
@jamesdmanton.bsky.social
@jsbeckwith.bsky.social @dgershlick.bsky.social @stevethechemist.bsky.social

10.06.2025 15:52 β€” πŸ‘ 12    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology.
Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available.

! Please share widely !

05.06.2025 20:35 β€” πŸ‘ 31    πŸ” 27    πŸ’¬ 2    πŸ“Œ 4
Photophysics and Photochemistry Group Early Career Meeting 2025

www.rsc.org/events/detai...

Come to this meeting magnificently organised by @rsc-photochem.bsky.social! Abstract deadline May 30, conference is 26–27 June in London, and I am baffled and happy to be an invited speaker alongside some really great people.

#photochem #photophysics #microscopy

01.05.2025 10:40 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Section 28 was "the law" too - that doesn't change the fact that the people who supported it were doing so out of bigotry.

22.04.2025 19:42 β€” πŸ‘ 485    πŸ” 176    πŸ’¬ 6    πŸ“Œ 2
Someone holding a sign saying: Respect existence or expect resistance.

Someone holding a sign saying: Respect existence or expect resistance.

Parents holding up a sign saying: "this mum says trans rights are human rights" and "our beautiful daughter is trans."

Parents holding up a sign saying: "this mum says trans rights are human rights" and "our beautiful daughter is trans."

Someone holding a sign saying "you can't legislate us out of existence."

Someone holding a sign saying "you can't legislate us out of existence."

Someone holding a sign saying "i love my trans self. I love my trans friends."

Someone holding a sign saying "i love my trans self. I love my trans friends."

Today, thousands gathered across the country - from Hastings to London to Glasgow - to say: we will always stand with trans people.

Trans rights are human rights. πŸ³οΈβ€βš§οΈ

19.04.2025 15:44 β€” πŸ‘ 1663    πŸ” 543    πŸ’¬ 18    πŸ“Œ 12
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🚨We have a 4-year ERC-funded PhD position available in the beautiful city of Leuven, Belgium, for building artificial nanomachines in lipid membranes.

Check out the details and apply here: www.kuleuven.be/personeel/jo...

Feel free to email me for more information!

18.04.2025 15:55 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Microscopy setup protocols A collection of Protocols and Tutorials covering a range of microscopy approaches, and including the build of microscopy setups and the use of microscopy ...

Today we share our Collection on protocols describing how to build and operate a broad variety of microscopy setups.

Let us know which one is your favourite microscope?

πŸ§ͺ πŸ”¬

17.04.2025 09:32 β€” πŸ‘ 22    πŸ” 11    πŸ’¬ 1    πŸ“Œ 2

A fringe group of bigoted weirdos have dragged British media, government, and law into their hateful obsession with trans people. Grim, depressing, and dangerous. Everyone with power in the UK who's played along should be ashamed of themselves.

16.04.2025 10:15 β€” πŸ‘ 998    πŸ” 328    πŸ’¬ 4    πŸ“Œ 7

Hi all---I sadly cannot make it to #FOM2025, would anybody want to take my registration? Feel free to ping me on here/forward to possibly interested people.

01.04.2025 14:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
PlayerOne cooled CMOS camera The Sony STARVIS and STARVIS2 image sensors are back-illuminated, have high QE and low readnoise (where STARVIS2 increases full well depth over STARVIS). Even though these sensors are marketed towards...

Just had the pleasure to experiment with a camera targeting the astronomy market, but offering great value for microscopy. Cooled, low noise (<1.5 e read-noise), high QE cameras that work with Micro-Manager can be bought for ~$1k: nicost.github.io/microscope-t...

29.03.2025 00:56 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Molecular Kinetics in Condensed Phases A guide to the theoretical and computational toolkits for the modern study of molecular kinetics in condensed phases Molecular Kinetics in Condensed Phases: Theory, Simulation and Analysis puts the fo...

www.google.com/books/editio...

perhaps?

21.03.2025 21:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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NEUBIAS Pasteur course on Bioimage Analysis - 2025 - Research Topics The exact schedule is still being finalized. Here is a description of the course content. Both tracks of the course have a specific focus onΒ hands-on and interactive tutorials. They are meant t...

Do you want to learn #BioimageAnalysis? Do you want to strengthen your skills?

We're thrilled to announce the #NEUBIAS Pasteur Course on Bioimage Analysis - May 2025! in @pasteur.fr Paris!

research.pasteur.fr/en/course/ne...

Details are on the page linked here, some info below πŸ‘‡

11.03.2025 14:08 β€” πŸ‘ 25    πŸ” 17    πŸ’¬ 2    πŸ“Œ 4
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Microscope objectives can be confusing, and detailed specs (or even basic properties) are often hard to find. Here's an introductory resource to help new builders and instrument designers with the basics. It's a work in progress so feedback is appreciated:

amsikking.github.io/microscope_o...

25.02.2025 17:06 β€” πŸ‘ 37    πŸ” 14    πŸ’¬ 1    πŸ“Œ 4

@jsbeckwith is following 20 prominent accounts