Drosophila as a model system to understand #collagen IV-related genetic disease. Learn how fly genetics and exploding brain tissue can inform on #ECM defects and pathological mechanisms. Team effort led by a very talented recent PhD graduate, Angus Nichols. doi.org/10.1016/j.ma...

Drosophila Genetic Database The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...

Super-resolution imaging in whole cells and tissues via DNA-PAINT on a spinning disk confocal with optical photon reassignment - Nature Communications Zaza and colleagues demonstrate that DNA-PAINT on a spinning disk confocal microscope with optical photon reassignment enables high-resolution imaging across large fields and imaging depths, resolving...

Great new DNA/Q-Paint method published by our @ucl colleague Sabrina Simoncelli - lucky to have been part of it! Check out the Ecadherin and collagenIV imaging in the fly retina at up to 15micron depth www.nature.com/articles/s41...

Another collagen IV paper on the "to read" list...
new review just out in the journal #matrix_biology
"The life cycle of type IV collagen" by David Sherwood
www.sciencedirect.com/science/arti...

Curious about collagen??
There is an amazing program for the Collagen Gordon in New Hampshire this year.
We have ample speaker slots reserved for abstract submissions.

Come and join us!

www.grc.org/collagen-con...
July 6 - 11, 2025

www.grc.org/collagen-grs...
July 5 - 6, 2025

Doug,Rachel,Alex

Please add your reading list! Our shiny collagen IV paper is out now😎 Enjoy beautiful red and green images! Yes, I MUST do molecular characterization of this "beauty" collagen IV... My TO-DO list is too much😅

A reminder to colleagues interested in Cell-Matrix adhesion & anything ECM related that registration is now open for the Fibronectin, Integrins & related molecules Gordon Research Conference. Incredible list speakers! incredible location! it will 🔥 🔥 🔥 Please join us! www.grc.org/fibronectin-...

A membrane proximal actin probe (MPAct) in fly macrophages unveils an actin cortex interconnected with the lamellar network. The homeostatic balance of these two actin networks is coordinated by the cortical-regulator, Moesin. Amazing work from @besaizsanchez.bsky.social and team.
rdcu.be/d8Yxr

For anyone interested in #extracellularmatrix. From fundamental questions in #DevBio to alterations in disease using interdisciplinary approaches across model organisms. And in an amazing research environment in Manchester (with some occasional fun in London 😀)!

Only 3 days left to apply! Postdoc positions available in the Röper lab at the University of Cambridge!
@PDN_Cambridge
Discover the role that supracellular cytoskeletal assemblies and crosstalk play in sculpting organs in Drosophila or human organoids in culture!
Links below!

📣 Everything you always wanted to know about the #ECM (but were afraid to ask). Join me at @themeshwork.bsky.social seminar series in December to learn about the latest developments of the #Matrisome project @matrisome.bsky.social! Sign up here forms.gle/W3QFUheh9hf5... and help us spread the word!