Susanne Kooistra

Beyond the nuclear border: single-cell analysis of in situ sequenced human brain tissue using cellular features - Communications Biology Investigating the suitability of different strategies for transcript allocation, including nuclear borders, expanded nuclear borders, and post-run immunostaining masks, for in situ sequencing data gen...

I'm very happy to share that our work describing a geospatial approach to allocating transcripts for single cell spatial transcriptomics (in human brains) using the 10x Xenium platform is now out in @commsbio.nature.com! @barteggen.bsky.social @kooistrasm.bsky.social

www.nature.com/articles/s42...

Dear Roman. We got the samples from the Netherlands Brain Bank. Unfortunately they do not register the specific sampling location for MS cases. So I am afraid we don't have that information.

Special Issue: Glial omics: Unraveling mechanisms in health and disease: Glia: Vol 73, No 3 Glia is the top neurobiology journal for research into glial cells (also called gliocytes or neuroglia). Articles cover all aspects of glial cell biology in health and disease.

#GliaPapers #GliaSpecialIssue
SPECIAL COVER

SPECIAL ISSUE: Glial omics: unraveling mechanisms in health and disease
onlinelibrary.wiley.com/toc/10981136...

Editorial Unboxing “Omics” in Glial Biology to Understand Neurological Disease here - onlinelibrary.wiley.com/doi/10.1002/...

#GliaPapers #GliaSpecial2025 REVIEW

@kooistrasm.bsky.social, @lschirmer.bsky.social

Multiple sclerosis: glial cell diversity in time and space
onlinelibrary.wiley.com/doi/10.1002/...

Thanks Lucas! Was great to work on this together.

Multiple Sclerosis: Glial Cell Diversity in Time and Space Glial cells and their subtypes are key drivers of lesion progression in multiple sclerosis with roles in both tissue damage and repair depending on the surrounding tissue environment and the function....

Happy holidays with a new review about what glial cells are doing in MS patholoy featuring latest developments and tools, thanks @kooistrasm.bsky.social for teaming up and putting this together - have fun reading: onlinelibrary.wiley.com/doi/10.1002/...

go.bsky.app/Lyzro3M

!WELCOME!

thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.

apologies for missing many of you - please do reply to get added

and remember to repost so the newbies can find us!

This is so helpful. Just joined and was wondering how I would find everyone. This was the very first post i saw😃. Would love to be added