Tom Fardon

I stole this response from that thread on TwittX, but it’s too good not to share. The tower is clearly a brotherhood of Nod reference.

This was not uncommon in the shipyard areas of Glasgow and Dundee.

My #BTSWinter2024 experience, starting and finishing back in Dundee.

Travel home from #BTSWinter2024. Long days, jam packed with great people doing great work in the Respiratory world. Saw a lot of old friends, too many to mention. Good conference, would recommend. 5 stars.

@tasha_rupani finishing up the transforming services session. Great to have so many people in the room. #BTSWinter2024 has been a buzz all week.

Self promotion post. Thanks for the invite #BTSWinter2024

Karl Staples faces everyone’s nightmare scenario on stage - “Ah, this is the wrong slide set”. Battling on @BTSWinter2024

➡️ Do not prescribe short-acting beta2 agonists to people of any age with asthma without a concomitant prescription of an ICS. [BTS/NICE/SIGN 2024]

Safety, pharmacokinetics, and early bactericidal activity of quabodepistat in combination with delamanid, bedaquiline, or both in adults with pulmonary tuberculosis: a randomised, active-controlled, o... In this 14-day trial, quabodepistat plus delamanid plus bedaquiline, a novel three-drug combination, appeared to be safe, well tolerated, and provided robust early bactericidal activity in adults with...

First data of a quabodepistat containing novel regimen for drug-susceptible TB
🆕️✨️OL RCT
Safety, pharmacokinetics, and early bactericidal activity of quabodepistat in combination with delamanid, bedaquiline, or both in adults with pulmonary TB #idsky #tbsky
www.thelancet.com/journals/lan...

I have similar feelings every time I go to conference, those of sonder, and Douglas Adams' Total Perspective Vortex.

Professor Quint - has she brought her glasses? #BTSWinter2024

I asked your question. The answer was that the normal range is not very variable, 0.4-0.5. So go with your local ULN.

Cervical Cancer Mortality Among US Women Younger Than 25 Years This study examines trends in cervical cancer mortality in US women aged younger than 25 years before and after the introduction of human papillomavirus vaccines.

The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...

Asthma guidelines session begins. #BTSWinter2024.

A Rob Horne shaped hole in the Asthma Guideline Implementation session at #BTSWinter2024. His dulcet tones waft over the Churchill Auditorium, still.

And why 50?

This is the problem, as you say. Ours is 0.01-0.4. But we use 0.3 for some Biologics and 0.15 for others. Uncertainty leads to these non-decisions. There’s nuance here, and it’s hard when the phenotypes are so different. I’ll ask the question. To me, >0.4 is abnormal.

Gráinne D’Ancona suggesting SABAs should be a controlled drug???? #BTSWinter2024 there’s more nuance to the SABA-free future.

I can try! “Above lab normal range” was suggested at one point. I’ll interrogate the ringleaders.

Never prescribed it. (TBF it wasn’t SMC approved)

People didn’t stop their atrovent/combo vent when they started the Spiriva: they went into urinary retention, I recall.

Shared decision making in the new asthma guidelines. #BTSWinter2024

There was one NIV machine in the RIE in 2001, in a big wooden box. So it had just snuck in. I’ll give you LAMA, now I think of it. I think Spiriva came in around 2002…?

Implementing guidelines, changing behaviours. Translating trials to patients. Lynn Elsey. #BTSWinter2024. Rob Horne currently awol - put up a flare?

@Prof Alice Turner in the distance there - NRAP quality improvement work. Prevention. Earlier accurate diagnosis. Self management. Timely access to optimal care. Reassuringly close to RCAPS. #BTSWinter2024

NRAP data deep-dives at #BTSWinter2024. Apologies for the crap photo - but only 23% patients with COPD exacerbations (presumably) admitted to a resp ward? And less than half seen by a resp specialist post-take? Eye-opening stuff.

NRAP session at #BTSWinter2024. We can’t do this in Scotland, for various reasons. But there must be a great deal to learn here for what we do. Or should be doing.

Neil Greening: "There have been no new treatments for COPD during my career". Me neither, Neil. #BTSWinter2024

I tell the med students the same chat, about clinics, etc.

#BTSWinter2024 kicks off now. Biologics in COPD.