This @alsassociation.bsky.social grant will support critical preclinical studies needed for our IND filing and help validate our identified biomarkers—to identify patients likely to respond to treatment.
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What makes this particularly promising is that our therapeutic approach has shown potential to:
• Reduce key ALS disease markers
• Enhance neuronal survival
• Work across multiple forms of ALS, including both genetic and sporadic cases, particularly C9orf72
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Our focus? A novel brain-penetrant CSF1R inhibitor that reprograms microglia—the brain's immune cells—from harmful to protective states.
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Exciting news! Modulo Bio has secured a $500k research grant from @alsassociation.bsky.social's Lawrence and Isabel Barnett Drug Development Program to advance our groundbreaking work in ALS and FTD treatment.
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Senior Lecturer and UK DRI Group Leader at King's College London | Epigenetic regulation in neurodegenerative diseases | https://www.kcl.ac.uk/people/sarah-marzi
Developmental neurobiologist, microglia, neuroimmune and immunovascular interactions, environment.
Group leader at CIRB, Collège de France, CNRS
Neuroscientist, in love with microglia (and cycling). Views are my own
Postdoc at Mancuso Lab | VIB, Belgium.
Microglia, CRISPR, AD & some single-cell bioinformagic 🧫🐭🔬
Scientist wannabe.
Postdoc @ VIB CMN UAntwerp & VIB CBD KU Leuven / Microglia, synapses, TurboID, and AD
Stem cell biologist using iPSCs to model neuroinflammation and Alzheimer’s disease at the New York Stem Cell Foundation. Previously: PhD @EdinburghUni, RA @CambridgeUni, MSc @BristolUni. she/her
Postdoc in Talbot Lab at Oxford Motor Neuron Disease Centre @mndoxford.bsky.social and Junior Research Fellow at Kellogg College Oxford, using iPSC models to research microglia-motor neuron interactions in ALS/MND.
MD/PhD. Neuroscientist and Neuroradiologist. On a journey to apply cell biology to new ways of imaging the brain. Alzheimer's disease researcher. President of the Portuguese Society for Neuroscience 🧠
Ph.D student in the Looger lab at UC San Diego.
Alzheimer, APOE, Actin, Txn factors, Immune, Tau, miRs, Drugs | Single cell & Spatial omics, Proteomics, QTL | ASO, RNAi, AAV | Mouse, iPSC, Drosophila, Zebrafish | Microglia, Astrocytes, Oligodendrocytes https://medicine.iu.edu/faculty/41977/kim-jungsu
Neuroscientist, Assistant Research Professor @IUSM Stark Neurosciences Research Institute
ARUK-RAD Fellow at the University of Dundee. I use proteomics to understand how microglia contribute to Alzheimer's Disease. GK for TNT Netball Club.
Professor of neuroscience at U. Bordeaux, France. Neuroimmunology enthusiast exploring how nutrients influence microglia-neuron crosstalk.
Assistant Professor, Biomedical Engineering at UAB I Alumna @Duke BME @curamdevices l Bridging Neuro-engineering and glycans I she/her I Views my own https://glycans4regeneration.com/
neuro nerd. aspiring artist. UIowa PhD - Pharmacology. Interested in neuro-immune interactions in the spinal cord. my opinions are my own. they/them
She/her • PhD candidate at Baylor College of Medicine studying neuroinflammation and lysosomal dysfunction • Interested in all things glia • 🧪🇲🇽 #LatinxInSTEM #firstgen #BLM
MCU / AP in Physiology in Sorbonne Université Paris France 👩🔬👩👧👦
Interested in how sex hormones shape the brain and behaviours #glia #endocrinedisruptors #neurons
Professor of Cell Biology, University of Seville. Microglia, Mitochondria and Endoplasmic Reticulum
PI @ CIID, Heidelberg, and @DZIF. Mom of two and scientist in love with nuclear architecture - NPC- RNA processing, metabolic switches in infected immune blood and brain cells 🧬🔬🧬🦠🧫
