π The revised version of CORNETO, our unified Python framework for knowledge-driven network inference from omics data, is published in peer reviewed form
π Paper: www.nature.com/articles/s42...
π News & Views: www.nature.com/articles/s42...
π» Code: corneto.org
π§΅ Thread π
22.07.2025 15:23 β π 61 π 29 π¬ 1 π 1
We are writing to all the Chancellorship candidates of Cambridge University asking them to commit to the creation of University Ombudsman
The Ombudsman would investigate violations of free speech, victimisation because of protected beliefs & characteristics, as well as other serious abuses
21.06.2025 18:25 β π 4 π 5 π¬ 0 π 0
Wyn is a dedicated academic with over 20 years of teaching and service to Cambridge. Not a celebrity, billionaire, or titled figure β he is one of us. A principled scholar with deep integrity, Neil has consistently championed the interests of students and staff alike.
19.06.2025 14:33 β π 3 π 1 π¬ 0 π 1
An enormous honour! Thank you @embo.org and @helloeacr.bsky.social!
This talk was only possible because of the amazing talent of @caldaslab.bsky.social and past #Caldasians!
19.06.2025 12:12 β π 13 π 6 π¬ 0 π 0
Excellent last keynote presentation by @carloscaldas1960.bsky.social highlighting recent key work from the @caldaslab.bsky.social Itβs a privilege to have completed my PhD in such a remarkable research lab! Excited for the forthcoming publicationsβstay tuned! @helloeacr.bsky.social #EACR2025
20.06.2025 08:19 β π 5 π 3 π¬ 0 π 0
Amazing presentation delivered by @masina_riccardo @helloeacr.bsky.social ! He presented our project using PDTCs as high-throughput drug screens, and it was selected as a proffered paper! @caldaslab.bsky.social
18.06.2025 22:02 β π 3 π 2 π¬ 0 π 0
@carloscaldas1960.bsky.social and the Caldasians will always #KeepResearchCurious and never stop doing good science!
#EACR2025
@helloeacr.bsky.social
18.06.2025 18:48 β π 15 π 4 π¬ 1 π 0
What a great day! @helloeacr.bsky.social and Caldasians assemble ! πͺπ»π
18.06.2025 00:28 β π 2 π 0 π¬ 0 π 0
snDNAseq of 40,000 cells from 140 tumors from #METABRIC. @mauriziocallari.bsky.social and @sc10021.bsky.social will soon write a major papers from this work! @caldaslab.bsky.social continues to produce outstanding science!
17.06.2025 23:03 β π 11 π 5 π¬ 0 π 1
@allanlui.bsky.social has discovered a synthetic lethal hit for ER+ breast cancer driven by ZNF703 amplification! Major stuff! @caldaslab.bsky.social walking the walk!
17.06.2025 23:06 β π 8 π 5 π¬ 0 π 1
The amazing @caldaslab.bsky.social is rocking #EACR2025! @helloeacr.bsky.social
17.06.2025 09:47 β π 13 π 4 π¬ 0 π 0
π§ decoupler 2.0.6 is out thanks to @paubadiam.bsky.socialβ¬, now as a core @scverse.bsky.social package scverse.org
This release includes a streamlined API aligned with scverse standards, updated vignettes, and a new one on pseudotime enrichment analysis π
decoupler.readthedocs.io/en/latest/
12.06.2025 06:36 β π 35 π 7 π¬ 0 π 2
@helloeacr.bsky.social #EACR2025 @caldaslab.bsky.social
17.06.2025 14:51 β π 3 π 0 π¬ 0 π 0
Such a beautiful project and a pleasure to work with @nguyenlab.bsky.social ! Please share and post our recent work @cp-cellreports.bsky.social from the @caldaslab.bsky.social and Rueda Lab!
12.05.2025 14:58 β π 4 π 0 π¬ 0 π 0
βBluesky has wonβ.
Please retweetβ¦ π
28.03.2025 08:13 β π 174 π 57 π¬ 3 π 4
YouTube video by Pathology Mini Tutorials
Prof I O Ellis - Major Breakthroughs in Breast Cancer Prognostification Over The Past 40 years:
I would have never had the career I have had if it was not for Ian Ellis! He is in nearly all of my major papers. #METABRIC is in great part thanks to him! @caldaslab.bsky.social celebrates an amazing breast pathologist and unique colleague! Thank you, Ian!!
youtu.be/tft8ass_IZs?...
28.03.2025 12:15 β π 4 π 3 π¬ 0 π 0
Congrats @timcoorens.bsky.social ! Beautiful work!
21.03.2025 18:08 β π 1 π 0 π¬ 1 π 0
The somatic mutation landscape of normal gastric epithelium - Nature
Whole-gene sequencing of microdissected gastric glands from individuals with and without gastric cancer reveals distinct patterns of somatic mutations and provides insights into influen...
The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our @nature.com paper:
www.nature.com/articles/s41...
20.03.2025 14:58 β π 40 π 16 π¬ 3 π 1
Really nice to hear about your work there!
14.03.2025 09:19 β π 1 π 0 π¬ 0 π 0
Proudly Caldasian! :)
13.03.2025 18:53 β π 2 π 1 π¬ 0 π 0
π€‘π€‘π€‘
11.03.2025 14:39 β π 4 π 2 π¬ 0 π 0
See you next week! We will host very exciting speakers! Donβt miss it!
27.02.2025 12:33 β π 0 π 0 π¬ 0 π 0
I am proud to be giving a keynote lecture at #EACR2025! I am very grateful to be presenting some of the seminal work done by the truly amazing @caldaslab.bsky.social, including unpublished work and our future scientific plans focusing on tumor ecosystems.
25.02.2025 13:55 β π 9 π 3 π¬ 0 π 0
Congratulations Dr Daniel Guerrero-Romero!! It is fantastic to see another PhD out of @caldaslab.bsky.social! This one on the mathematics of breast cancer xenograft growth.
04.02.2025 09:24 β π 8 π 4 π¬ 1 π 0
I feel very privilege not only for accomplished this but also for having the opportunity to learn and meet new people with wonderful backgrounds! Thanks for everything all of you! π
04.02.2025 08:53 β π 2 π 0 π¬ 0 π 0
And obviously the amazing Florian Markowetz for hosting me into his lab and let me being part of his group!
04.02.2025 08:53 β π 4 π 2 π¬ 1 π 0
Of course all this could have not been possible without the supervision of Oscar M Rueda and @carloscaldas1960.bsky.social ! So thank you again for giving me the opportunity to do a PhD with both of you!
04.02.2025 08:53 β π 1 π 0 π¬ 1 π 0
Engineering cells to understand their decisions
ESPOD Fellow @ebi.embl.org & @sangerinstitute.bsky.social
(Saez-Rodriguez & Parts)
lingering scientist @crick.ac.uk (Briscoe)
Head of Cancer computational biology group @ VHIO
Stanford & UoBristol postdoc, UDC PhD. RepunantiΓ±o
Evolution, cancer, immunology, math(s)
Ursula Zoellner Professor of Cancer Research
University of Cambridge
blundelllab.com
Computational Biologist, Head of research @ebi.embl.org, part-time
Heidelberg University, codirector DREAM challenges. For group's activities, see @saezlab.bsky.social
He/him. Computational Biologist. Lead multi-omic data analysis and integration with mechanistic prior knowledge in complex diseases @saezlab.bsky.social
Opinions are my own
Oncologist-Scientist @ Princess Margaret Cancer Centre & University of Toronto π¨π¦
Transcriptional plasticity, functional clonal heterogeneity, cancer stem cells π§¬π¬π§«
lvnguyenlab.ca
Chair, Computational BIology and Medicine Program, Princess Margaret Cancer Centre, University Health Network.
Associate Professor, Medical Biophysics, University of Toronto.
Disclosures: https://github.com/michaelmhoffman/disclosure/
The mission of the American Association for Cancer Research (AACR) is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research.
Leading biomedical #openaccess journal, bridging the gap between basic and clinical research. Part of The Lancet Discovery Science. IF=9.7
π https://www.thelancet.com/journals/ebiom/home
Bren Professor of Computational Biology @Caltech.edu. Blog at http://liorpachter.wordpress.com. Posts represent my views, not my employer's. #methodsmatter
π¨π¬ Putting cancer in context π¬π¨
Systems breast cancer pathology Lab at @cruk-ci.bsky.social @cancerresearchuk.bsky.social @cambridge-uni.bsky.social
Group Leader at Peter MacCallum Cancer Centre. Genomics, organoids, ovarian cancer
Account of the Saez-Rodriguez lab at EMBL-EBI and Heidelberg University. We integrate #omics data with mechanistic molecular knowledge into #opensource #ML methods
Website: https://saezlab.org/
GitHub: https://github.com/saezlab/
Cancer genetics at Imperial College London
- working on #breastcancer and #coloncancer, and a mix and match of cool side projects
βRetiredβ academic scientist, breast cancer genomics, University of Cambridge
Professor, Statistical learning in molecular medicine. Director Oslo Centre for Biostatistics and Epidemiology @ocbe.bsky.social, @uio.no & Oslo University Hospital. Posting in my own capacity. (Bio)statistics, climate breakdown, train journeys.