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Sophie Goldsmith

@sophie0g.bsky.social

๐Ÿซ๐ŸซงPhD student working with forebrain organoids & microglia to study FTD | Wray Lab, UCL ๐Ÿงซ๐Ÿง  & coordinate the GENFI participant engagement board! https://www.justgiving.com/page/sophie-goldsmith-3

303 Followers  |  364 Following  |  9 Posts  |  Joined: 06.11.2024  |  1.759

Latest posts by sophie0g.bsky.social on Bluesky

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A rare eye #Cancer which may have otherwise been missed, has been detected in a newborn baby enrolled in @genomicsengland.bsky.social WGS study: The Generation Study. Sophie Goldsmith writes in BioNews:
www.progress.org.uk/rare-eye-can...

#Cancer #EyeCancer #Gene #genomics #genetics #Genome #DNA

27.10.2025 18:18 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Super excited to be running the London Landmarks Half next April for The National Brain Appeal ๐Ÿง ๐Ÿƒ๐Ÿผโ€โ™€๏ธ just set up my just giving page - any donations / sharing my page would be FAB โญ๏ธ

www.justgiving.com/page/sophie-...

14.08.2025 15:26 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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What a treat to share a walkies and a BBQ with my colleagues.

The rain in the background caught us on the way home. But thatโ€™s normal for a British bbq, right?

21.07.2025 19:23 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Feat. @sophie0g.bsky.social presenting her organoid work! ๐Ÿง 

09.07.2025 20:38 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Thrilled to share that I passed my PhD upgrade viva yesterday!Extremely grateful for all the support Iโ€™ve had from my supervisors & team who have helped me get to this point & a big thank you to my upgrade panel for the insightful feedback & discussion. ๐Ÿงซ๐Ÿง  @selinawray.bsky.social

26.06.2025 11:00 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

New paper from the lab, under the leadership of @celarber.bsky.social !

21.06.2025 09:22 โ€” ๐Ÿ‘ 34    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Super exciting that The Brain at Rest is out! Was a huge privilege to be Joeโ€™s research assistant for this book, searching through all the research papers & learning so much in the process! Huge thank you to Joe for this opportunity to help out on such a fab project! Go give it a read โ˜บ๏ธ

19.06.2025 16:25 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Had a fantastic time at the FTDUK conference yesterday in Edinburgh โญ๏ธ๐Ÿง so many brilliant talks - exciting to hear about the cutting edge FTD research & clinical trials underway!

31.05.2025 09:20 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Webinars โ€“ GENFI

A recording of the talks will be available on the GENFI website in the coming weeks๐Ÿ˜€ watch the talks from last year here: www.genfi.org/participate/...

14.04.2025 12:41 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Was a huge pleasure to co-host the 2nd GENFI Participant Webinar on Friday! Nearly 100 attendees and a fantastic lineup of speakersโ€”thank you to everyone who joined and to all the speakers for their brilliant talks! Followed by a hugely informative participant engagement board roundtable!

14.04.2025 12:38 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Fab first day at the Stem Cell Models of Neurodegeneration conference in Edinburgh! ๐Ÿง  #SCMND So many exciting talks, and I really enjoyed presenting my poster with the work from the first year of my PhD! Looking forward to the rest of the conference! ๐Ÿงซ๐Ÿง 

26.03.2025 21:42 โ€” ๐Ÿ‘ 12    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This was so powerful - few of us can imagine the reality of having a family devastated by familial FTD - and the response of Jordan/Cian to their own risk is incredibly inspiring. Find them in instagram/TikTok as the FTD Brothers and follow their storyโ€ฆ!

25.02.2025 10:02 โ€” ๐Ÿ‘ 13    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
A Woman With a Rare Gene Mutation Fights to Avoid Her Motherโ€™s Fate (Gift Article) A mutant gene is coming to steal Linde Jacobsโ€™s mind. Can she find a way to stop it?


Hello BlueSky. One of our cofounders, Linde Jacobs, is profiled in The New York Times today. Itโ€™s a moving snapshot of what an FTD family goes through. Help us fight for therapies that can cure dementia for under 60s. #ftd #aftd #dementia #tau #alzheimers #mapt

www.nytimes.com/2024/12/22/h...

22.12.2024 14:57 โ€” ๐Ÿ‘ 138    ๐Ÿ” 29    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 8
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Getting some final images before going on Xmas break! ๐Ÿงซ๐ŸŽ„GFAP & Nestin staining in forebrain organoids using whole mount ICC ๐Ÿง 

19.12.2024 17:33 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Lab holiday photo 2024 โ˜บ๏ธโ˜บ๏ธ

Feat. @celarber.bsky.social @sophie0g.bsky.social @lecrawf0.bsky.social and many more not in the bluesky yet :)

12.12.2024 18:17 โ€” ๐Ÿ‘ 25    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Fantastic talk yesterday from @bowleslab.bsky.social discussing tau & iPSC models ๐Ÿง ๐Ÿงซ & was lovely to meet you after! โ˜บ๏ธ

27.11.2024 09:52 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Excited to share the lab's recent publication. Granulins are critical for lysosome function and brain health to prevent neurodegeneration. Our data suggest that granulin peptides could be used to treat frontotemporal dementia (FTD), Parkinsonโ€™s disease, Alzheimerโ€™s disease.
t.co/pN28kabjIA

21.11.2024 20:48 โ€” ๐Ÿ‘ 18    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

๐Ÿง  130 people now in this UK Dementia Starter Pack! ๐Ÿง 
๐Ÿ“ˆ (50 more than 2 days ago!) ๐Ÿ“ˆ

A great mix of Profs/PIs/Post-docs/PhDs/Technicians.

Please re-post so it can reach a wider audience as I'm sure there are more of us out there โ˜บ๏ธ๐Ÿฆ‹
go.bsky.app/S6FfsTp

21.11.2024 14:08 โ€” ๐Ÿ‘ 37    ๐Ÿ” 28    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 0
Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia - Acta Neuropathologica Mutations in ITM2B cause familial British, Danish, Chinese, and Korean dementias. In familial British dementia (FBD), a mutation in the stop codon of the ITM2B gene (also known as BRI2) causes a C-ter...

Very happy to share our paper on Familial British Dementia (FBD) which is online today!

Using patient iPSC,we show the amyloidogenic peptide in this disease -ABri -is mainly produced by microgliaโ€ฆ

Never heard of FBD? You wonโ€™t be the only oneโ€ฆ explainer incoming!

link.springer.com/article/10.1...

15.11.2024 12:53 โ€” ๐Ÿ‘ 123    ๐Ÿ” 18    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 3

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