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Robert Screaton

@roblab.bsky.social

scientist. regeneration. mitochondria. diabetes. cancer. views my own.

222 Followers  |  67 Following  |  81 Posts  |  Joined: 08.02.2024  |  1.4139

Latest posts by roblab.bsky.social on Bluesky

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Join us in Toronto, July 13โ€“16 for the inaugural International Conference on Neurogenesis & Repair!
Featuring keynote Jeffrey Macklis (Harvard) + global speakers.
13 competitive short talks, poster sessions, and separate trainee awards.
Earlyโ€‘bird deadline: March 31.

31.01.2026 23:11 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Queued up in the ๐Ÿ‡จ๐Ÿ‡ฆ National Graduate Course in #Islet Biology and #Diabetes today: experts @chrisadoucette.bsky.social and @theodoreds.bsky.social who will be discussing our current knowledge (and gaps!) on how #insulin actually gets out of a beta cell! Glucose coupling, circadian effects, and more!

28.01.2026 16:33 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸงฌWhat if #betacells arenโ€™t all the same?
Professor Andrew Pospisilik shares new epigenetic evidence that could reshape our understanding of #diabetes and #heterogeneity - from beta cell subtypes to #obesity endotypes.
๐Ÿ“บWatch now:๐Ÿ”— easd-elearning.eu/episode/359/...

21.01.2026 12:44 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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This week FRIDAY JAN23 at NOON CST we are thrilled to welcome @glim2016.bsky.social from @umontreal.ca @crchum.bsky.social to the pharmacology seminar series speak "Can we identify 14-3-3 zeta inhibitors to treat type 1 #diabetes" @dream-diabetes.bsky.social Join us Via ZOOM: 660 7073 7150 PW:594459

21.01.2026 02:34 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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a woman wearing sunglasses and a blue shirt is making a funny face and saying `` no autographs please '' . ALT: a woman wearing sunglasses and a blue shirt is making a funny face and saying `` no autographs please '' .

Today in the ๐Ÿ‡จ๐Ÿ‡ฆ National Grad course in #Islet Biology and #Diabetes we welcome superstars Cristina Nostro and @yassiag.bsky.social to discuss the latest on using #stemcell derived islet cells as a strategy to treat (cure?) #T1D!

21.01.2026 16:36 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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For ~century, weโ€™ve asked: why do proliferating cells ferment glucose even when O2 is around? Iโ€™m thrilled to share our latest work @natmetabolism.nature.com, led by @thebiokimist.bsky.social. By leveraging conditional essentiality in HPLM, we propose a provocative new answer to this classic Q. ๐Ÿงต

16.01.2026 16:26 โ€” ๐Ÿ‘ 55    ๐Ÿ” 27    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 2

Will be discussing science communication today in the ๐Ÿ‡จ๐Ÿ‡ฆ National #Islet and Diabetes graduate course - using the #betacell secretion coupling debate as a case study! @utoronto.ca

14.01.2026 17:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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a man in front of a microphone with the words we 're back on his face Alt: Neil deGrasse Tyson in front of a microphone mouthing the words "We're Back"

The 6th Annual ๐Ÿ‡จ๐Ÿ‡ฆ National Graduate Course in #Islet Biology and #Diabetes hosted at @utoronto.ca kicks off today with 21 students and 30 outstanding lecturers from around the world. Today Drs. Wicklow and Gerstein will talk about #T2D and GDM in indigenous populations and the latest on #remission.

07.01.2026 17:32 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Study shows that neonatal #betacells sense gut microbiota-derived #bileacids via #FXR, limiting their development. Declining postnatal beta cell FXR expression allows normal neonatal beta cell growth and reduces #diabetes risk link.springer.com/article/10.1...

22.12.2025 16:40 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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(please share) Immediate #postdoc job opening in the Millman lab at WashU Med (St. Louis, MO).

Want to develop next-generation pancreatic islets for the study and treatment of diabetes? Email your CV to apply

sites.wustl.edu/millmanlab/

19.12.2025 20:25 โ€” ๐Ÿ‘ 22    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Limitations in PPARฮฑ-dependent mitochondrial programming restrain the differentiation of human stem cell-derived ฮฒ cells - Nature Communications Here they show that PPARฮฑ-dependent mitochondrial programming promotes the differentiation of pluripotent stem cell-derived ฮฒ cells. Targeting mitochondria has the potential to improve ฮฒ cell replacem...

Lietzke et al. demonstrate that pluripotent stem cell-derived ฮฒ cells exhibit reduced oxidative and mitochondrial fatty acid metabolism compared to primary human islets, which is related to limitations in key mitochondrial transcriptional networks. ๐Ÿงช
#PancSky

www.nature.com/articles/s41...

12.12.2025 09:52 โ€” ๐Ÿ‘ 5    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Download our large database of postdoc fellowships in all fields of research.

Database freely available to all; 281 fellowships.

Download here: research.jhu.edu/rdt/funding-...

13.12.2025 13:38 โ€” ๐Ÿ‘ 87    ๐Ÿ” 68    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 4
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Spatial and morphological organization of mitochondria in neurons across a connectome Neuronal function depends on mitochondria, but little is known about their organization across neurons. Using an electron microscopy Drosophila connectome, we uncovered quantitative rules governing th...

Spatial and morphological organization of mitochondria in neurons across a connectome | Science www.science.org/doi/10.1126/...

11.12.2025 19:26 โ€” ๐Ÿ‘ 13    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Our Novo Nordisk Research Chair in Equitable Care of Diabetes and Related Conditions, Dr. Baiju Shah, was interviewed about the importance of including diverse populations in research. Check out this video podcast from the T2D Network and @kristalamb.bsky.social!

www.youtube.com/watch?v=SGIG...

01.12.2025 20:25 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Insulin production is sustained during DNA damage-mediated senescence in adult human beta cells - Diabetologia Aims/hypothesis Residual pancreatic beta cells in type 1 diabetes show reduced insulin production but the mechanisms remain unclear. Beta cells undergo stress responses during type 1 diabetes, includi...

How is #insulin production affected in residual beta cells in type 1 #diabetes? Prรฉfontaine et al show unexpectedly that stressed senescent beta cells continue to produce mature insulin in the context of type 1 diabetes #DiabetesResearch #T1D #Islets link.springer.com/article/10.1... ๐Ÿ”“

26.11.2025 12:34 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Islet Biologists in ๐Ÿ‡จ๐Ÿ‡ฆ ๐Ÿ† @cirtn.bsky.social

26.11.2025 03:45 โ€” ๐Ÿ‘ 17    ๐Ÿ” 9    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine.

If you think the world doesnโ€™t need Basic Science, or that somehow Science has failed you, think again.

#sciencematters

25.11.2025 01:40 โ€” ๐Ÿ‘ 3510    ๐Ÿ” 1025    ๐Ÿ’ฌ 88    ๐Ÿ“Œ 43
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Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress - Diabetologia Aims/hypothesis Accumulation of islet amyloid polypeptide (IAPP) and amyloid formation is associated with beta cell dysfunction and cell death in human islets and may also contribute to graft failure ...

Bri2 BRICHOS domain inhibits cytotoxic IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress. #T1D #SC-islets #CellTherapy
link.springer.com/article/10.1... ๐Ÿ”“

21.11.2025 12:51 โ€” ๐Ÿ‘ 7    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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๐Ÿ—จ๏ธ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)

11.11.2025 12:52 โ€” ๐Ÿ‘ 62    ๐Ÿ” 34    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2

A future star in ๐Ÿ‡จ๐Ÿ‡ฆ diabetes research

14.11.2025 17:27 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Diabetes in four dialects: a global call for equity across lived, loved, learned and laboured experiences - Diabetologia Diabetologia -

Diabetologia supports this yearโ€™s #WorldDiabetesDay focus on diabetes and well-being. Well-being is key to peopleโ€™s lived experiences of diabetes around the world, and we were honoured to explore this through the voices of PLWD in our recent special issue link.springer.com/article/10.1...

14.11.2025 09:08 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2

๐ŸŽ‰Very excited to share our new work on senescence and insulin processing now out in @DiabetologiaJnl link.springer.com/article/10.100โ€ฆ
Fantastic effort by my @dream-diabetes.bsky.social trainees, along with @yichunchen.bsky.social @bruceverchere.bsky.social
@cirtn.bsky.social

14.11.2025 03:33 โ€” ๐Ÿ‘ 17    ๐Ÿ” 7    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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During the workday, people living with #diabetes may need time for blood sugar checks, insulin and breaks.

Remember:
๐Ÿ’ฌAsk how you can support.
๐Ÿ‘‚Listen to what they need, or do not need, from you.
๐Ÿ™…โ€โ™€๏ธBlaming and shaming is never helpful.

Learn more๐Ÿ”—bit.ly/4844grn #WorldDiabetesDay

14.11.2025 10:20 โ€” ๐Ÿ‘ 68    ๐Ÿ” 28    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Happening TODAY! Join us in 500 JBRC for the 7th Annual DREAM Trainee Lectureship, where Dr. Hertzel Gerstein (@mcmasteruniversity.bsky.social) will present on "Type 2 Diabetes Remission: The Quest" from 12 - 1 p.m. Don't miss this! @chrimanitoba.bsky.social @um-radyfhs.bsky.social

14.11.2025 15:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Can we prevent Type 1 Diabetes in Canada? Join the CanScreen T1D Symposium at @diabetescanada.bsky.social's preconference!

๐Ÿ“… Nov 26, 2025 | ๐Ÿ•’ 2:45 - 4:15 PM | ๐Ÿ“ Toronto
โœ… Screening, prevention, family insights, and how to get involved

๐Ÿ”— Register: bit.ly/4nyxy79
#Diabetes #Type1Diabetes #Symposium

31.10.2025 17:37 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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What a gem from @dudinlab.bsky.social @gautamdey.bsky.social @centriolelab.bsky.social in Cell! Expansion microscopy atlas of >200 eukaryotes comparing cytoskeletal architectures revealing structures not seen before. Stunning visualisation! Exactly the kind of transformative cell biology we need.

31.10.2025 17:43 โ€” ๐Ÿ‘ 137    ๐Ÿ” 55    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1
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Discover MyRoad, a platform supported by CIHR, offering research training & mentorship in #obesity, #diabetes & #cardiometabolic #diseases. New opportunities this fall include cohort training, travel awards & more. ๐ŸŽ“โœˆ๏ธ
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca

02.09.2025 18:46 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

this is why we put a runner on second

28.10.2025 06:01 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

but the dodgers are better ๐Ÿ˜›

25.10.2025 05:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The Dome is going to collapse.

After Addison Barger hit the first pinch-hit home run in World Series history, Alejandro Kirk just went yard. Theyโ€™ve scored 9 in the 6th.

Itโ€™s 11-2 #BlueJays

25.10.2025 02:37 โ€” ๐Ÿ‘ 315    ๐Ÿ” 38    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 2

@roblab is following 20 prominent accounts