Vassilis Papalazarou

I'm deeply honoured to receive the BACR/AstraZeneca Young Scientist Frank Rose Award in recognition of my cancer research.
Grateful to @thebacr.bsky.social @astra-zeneca.bsky.social ‬ #Mentors & #Colleagues whose support has shaped this journey.

My reflections👇
🔗 www.bacr.org.uk/news/2025-ba...

Exciting work, very happy to see it published! Huge congrats @gounismichalis.bsky.social and team! 😀

1/ Beyond thrilled to see my #PhD work now published in @jcb.org
A short thread (🧵) for #metastasis #metabolism #ExtracellularVesicles (EVs) aficionados

In Memoriam: Wolfenson, Giannone, and Schwartz recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025. rupress.org/jcb/article/...

Cellular and organismal function of choline metabolism - Nature Metabolism

REVIEW | Kıvanç Birsoy, Monther Abu-Remaileh and colleagues @rockefelleruniv.bsky.social, @stanford.edu

The authors provide a broad overview of choline metabolism, its cellular handling, and how it impacts physiology and pathology.

https://bit.ly/3WPCPM2

Huge congrats Martha, well deserved!!! 🥳☺️

🔔🧪 I'm deeply saddened by the passing of Michael Sheetz, a true pioneer in #mechanobiology.
I'll always cherish our lovely times in NYC, Singapore, Zurich, and Sydney. My heartfelt condolences to his family and friends in this difficult time.
So long, Mike 🥺😔

Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers in metazoans Branched actin networks nucleated by the Arp2/3 complex play critical roles in various cellular processes, from cell migration to intracellular transport. However, when activated by WISH/DIP/SPIN90 fa...

Arp2/3 nucleates bidirectional linear actin filaments when activated by SPIN90 !!! www.biorxiv.org/content/10.1...

A multimodal imaging pipeline to decipher cell-specific metabolic functions and tissue microenvironment dynamics Nature Protocols - Evaluating the metabolic organization of complex tissue microenvironments is useful for understanding cellular function within tissues. This protocol describes a multimodal...

Our new imaging protocol in @natureportfolio.bsky.social provides a unique way to study metabolic interactions in the tumour microenvironment. #ImmunoSky

Read it here - rdcu.be/d7WGO

doi.org/10.1038/s415...

Thanks to my collaborators: @kreuzaler.bsky.social @crick.ac.uk
@cancergrand.bsky.social

YouTube video by Francis Crick Institute How Does Cancer Hack Our Cells? - with Gerard Evan

What is cancer and why is it so difficult to treat?

Crick group leader Gerard Evan explains why we get cancer and how he and other scientists are working to unravel this complex disease.

www.youtube.com/watch?v=i8gP...

If the UK wants to lead in AI, it must fund more PhDs Universities are the cornerstone of the country’s reputation as a global research hub but the business model is in crisis

If the UK wants to lead in AI, it must fund more PhDs.
Or in medicine. Or in Chemistry. Or anything.

www.ft.com/content/a656...

132. Why Britain Isn’t A “Science Superpower” The Rest Is Money · Episode

Our director Paul Nurse chatted to Robert Peston and Steph McGovern on The Rest is Money about science funding this week.

Paul discussed what it will take for the UK to become a ‘Science Superpower,’ as well as his story of discovering his own genetic history.

open.spotify.com/episode/6kxv...

This is always my favorite scientific event of the year! Super exciting science and the best vibes. Really looking forward to CMSW again this year :)

Hi all, our lab will soon recruit a PhD student working within a very exciting MSCA Horizon Doctoral network working on ageing, UNION, which gathers some fantastic scientists. Please apply if your profile fits our project (see attached advert).
Looking forward to working with you!

Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet Morrison and colleagues show long-chain fatty acid oxidation has context-dependent effects on hematopoietic stem cells (HSCs). It is dispensable for HSC function in young mice. It becomes necessary for normal HSC function and hematopoiesis in older mice. A high-fat diet increases fatty acid oxidation, and this impairs HSC function.

Congrats to Salma Merchant for Cell Stem Cell paper: the effects of fatty acid oxidation in hematopoietic stem cells are context dependent. FAO is not necessary in young HSCs, but becomes necessary during aging, and is deleterious when upregulated by a high fat diet.
www.cell.com/cell-stem-ce...

I took a break from work to protect my health. This should be more accepted in academia Better support structures would “lead to a more inclusive, productive, and humane workplace for everyone,” this physician-scientist writes

I applaud this, and I had to do something similar recently. Don't forget, we are only humans

I took a break from work to protect my health. This should be more accepted in academia

www.science.org/content/arti...

The AI revolution is running out of data. What can researchers do? AI developers are rapidly picking the Internet clean to train large language models such as those behind ChatGPT. Here’s how they are trying to get around the problem.

The sad realistion that someone will have to do experiments at some point....damn it

"The AI revolution is running out of data. What can researchers do?"

www.nature.com/articles/d41...