Effective targeting of PDGFRA-altered high-grade glioma with avapritinib
PDGFRA is commonly altered in pediatric HGG. Mayr etย al. report that the PDGFRA/KIT
inhibitor avapritinib demonstrates on-target activity, brain penetrance, and survival
benefit in pre-clinical H3K27M...
Thrilled to share our work with Mariella Filbin, Johannes Gojo and Carl Koschmann, now published in @cp-cancercell.bsky.social We present a translational approach identifying the PDGFRA inhibitor avapritinib as a novel targeted treatment for pHGG with PDGFRA alterations www.cell.com/cancer-cell/...
13.03.2025 15:30 โ ๐ 8 ๐ 2 ๐ฌ 1 ๐ 0
Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma
Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...
First ๐ฆ post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A ๐งต
08.01.2025 17:13 โ ๐ 132 ๐ 40 ๐ฌ 3 ๐ 8
Would love to be added as well. Thank you!
19.11.2024 13:40 โ ๐ 1 ๐ 0 ๐ฌ 1 ๐ 0
Associate Professor of Neurology, Harvard Medical School/ Massachusetts General Hospital
The ASCI is a nonprofit honor society of physician-scientists. Founded in 1908, the Society is home to over 3,000 members active across academic medicine and industry.
https://the-asci.org
Chief Editor of Nature Biomedical Engineering. Ph.D. Previously at Nature Methods. @rita_strack on the place formerly known as twitter.
Neurobiologist studying retinal development and regeneration. @IRCM @UdeMontreal @McGill U. Proud dad of an amazing transgender boy. LGBTQ+ ally.
https://orcid.org/0000-0003-4655-9048
Assistant Professor, investigating how the brain generates skilled movements.
(she/her)
Public transport and bicycle enthusiast
Views are my own
Neuroscientist by day ๐ฌ๐งซ Sassy, queer immigrant all the time ๐ณ๏ธโ๐๐ฎ๐น He/they
Postdoc in the Liddelow lab @NYULH previously found @HSCRB @StanleyCentre
The wanderer. The clown. The chairman.
President and CEO, @alleninstitute.org
Opinions are my own.
Aging lab @Stanford. Our interests include mechanisms of aging, brain aging and rejuvenation, neural stem cell aging, genetics of lifespan and suspended animation in killifish
Independent expert voice of biomedical and health research in the UK, fostering good health for all supported by the best research.
Visit https://bit.ly/acmedsci for more info.
Obesity and neurodegeneration researcher and entrepreneur discovering new treatments using iPSC and mouse models.
A monthly reviews journal covering exciting developments in all areas of neuroscience.
Studying how balance develops, functions, and fails at NYU Langone. http://www.schoppiklab.com .
"And worse I may be yet: the worst is not so long as we can say, 'This is the worst.โโ -- King Lear (Act IV Scene I)
A film about Ben Barres a transgender neuroscientist, who fought for women, LGBTQ+ and the marginalized in stem join us https://askthequestionmovie.com
Psychiatry | AI | Cancer Neuroscience ๐ง MD Anderson | Heidelberg
Cancer Neuroscience Heidelberg is funded by the European Center for Neurooncology (EZN) - Dietmar Hopp Stiftung
I study neuro-glia-immune interactions in brain and gut with my wonderful lab in UKDRI at UCL
Stanford, cell cycle, RB, cancer, SCLC, mouse models
Official Bluesky account of Stanford Neurology & Neurological Sciences Department, Stanford University, California #Neurology ๐ง