Ale Mongera

We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...

Super cool! Looking forward to trying this reporter!

So nice!

@ucl-cdb.bsky.social @ucl.ac.uk @ucllifesciences.bsky.social @wellcometrust.bsky.social

📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉

Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...

Nice!

Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬

📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden

Register now (Deadline 31 July 2025): engineering-life-dresden.de

After 15 years of controversy, Science retracts ‘arsenic life’ paper Science has retracted a 2010 paper describing a strain of bacteria that purportedly substituted arsenic for phosphorus, an element present in all known life. Science/AAAS Fifteen years after publis…

After 15 years of controversy, @science.org retracts ‘arsenic life’ paper

Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1

Great thread by @amichaut.bsky.social

Check out this thread I wrote for @epimechfc.bsky.social ⬇️

Congratulations @clementrodier.bsky.social @frankschnorrer.bsky.social et al!

SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...

Universality in the Mechanical Behavior of Vertex Models for Biological Tissues A systematic comparison of diverse cell packing models reveals shared mechanical rules that govern how tissues stiffen, yield, and reorganize---shedding light on the physical logic behind morphogenesi...

Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...

So cool, Brent!

SAVE THE DATE!! #2026SDB
🧪🧬🔬🧫🎉
(Never been to Vegas 😂 Exciting!!)

Group photo from the Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism Workshop Held at Buxted Park, East Sussex, UK 22-25 June 2025

The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism

Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.

#Workshop #Biology #CellBiology #Community #Collaboration #Research

A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1

Beautiful work as always from the @bhamlalab.bsky.social ! Flamingoes use swirling flows to trap and catch preys!

📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

The Coming Out of a Transgender Scientist "I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

The role of extracellular matrix viscoelasticity in development and disease - npj Biological Physics and Mechanics npj Biological Physics and Mechanics - The role of extracellular matrix viscoelasticity in development and disease

Thrilled to share our new review article!
“The role of extracellular matrix viscoelasticity in development and disease” written together with Olivia Courbot is now published in npj Biological Physics and Mechanics. www.nature.com/articles/s44...
#ECM #Mechanobiology #DevelopmentalBiology

Amen

Curious about how percolation theory enable understanding the impact of mechanical heterogeneity in model breast cancer cells check this by Leo Camillo Chiara and joseph #giavazzi, #Voituriez
doi.org/10.21203/rs....

Adhesion-driven tissue rigidification triggers epithelial cell polarity The active regulation of tissue material properties via phase transitions is central in morphogenesis. Transitions abruptly occur at critical points in diverse control parameters, including cell densi...

🔗 You can read the full story here:
www.biorxiv.org/content/10.1...
#DevBio #Mechanobiology #Biophysics

A computational pipeline for spatial mechano-transcriptomics - Nature Methods The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.

🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...

Beautiful work, congratulations !!

Extracellular volume expansion drives vertebrate axis elongation Michaut et al. show that presomitic mesoderm explants autonomously elongate by a graded increase of the extracellular volume. Explant elongation mainly depends on cell activity and little on prolifera...

Extracellular volume expansion drives vertebrate axis elongation: Current Biology www.cell.com/current-biol...