@mongeralab.bsky.social
Developmental biologist at UCL Multicellular Morphogenesis Lab http://zebrafishucl.org/mongera-lab
Cover of the December 1996 issue of Development that describes the results of The Big Screen.
With more than 2.1k citations, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the CNV Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts π§ͺ
29.11.2025 06:29 β π 12 π 3 π¬ 1 π 0
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Thought I was being really novel when I designed and 3D printed this mold for zebrafish transplants based on the microinjection one, but found out today it already existsβ¦
Bottom: my PLA mold thatβs bent from warm agarose
Top: a very kind (more robust looking) gift from @mongeralab.bsky.social
Cell type-independent timekeeping gene modules enable embryonic stage prediction in zebrafish https://www.biorxiv.org/content/10.1101/2025.11.12.688039v1
13.11.2025 20:34 β π 7 π 4 π¬ 0 π 1Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
12.11.2025 15:35 β π 8 π 6 π¬ 0 π 0
How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework?
We propose to think along Marr's 3 levels: computational problem, algorithm, implementation
Check out our review:
arxiv.org/abs/2510.24536
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RTπ
π About our lab: renew.science/principal_in...
π PhD position: jobportal.ku.dk/phd/?show=15...
π§ͺ Postdoc position: jobportal.ku.dk/videnskabeli...
π¨ Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! π£π¬
This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!
www.findaphd.com/phds/project... π§ͺ
Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI
31.10.2025 11:24 β π 17 π 8 π¬ 0 π 1
Happy birthday to #LaskerLaureate Christiane NΓΌsslein-Volhard! She identified 120 genes involved in specifying embryonic pattern development.
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM π§ͺ
ΓgΓ¦tis byrjun
Sigur Ros
1999
We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...
10.10.2025 11:48 β π 4 π 8 π¬ 1 π 0Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.
More here: elifesciences.org/reviewed-pre...
Super cool! Looking forward to trying this reporter!
26.09.2025 11:26 β π 1 π 0 π¬ 0 π 0So nice!
22.09.2025 09:54 β π 1 π 0 π¬ 0 π 0@ucl-cdb.bsky.social @ucl.ac.uk @ucllifesciences.bsky.social @wellcometrust.bsky.social
11.09.2025 12:26 β π 0 π 0 π¬ 0 π 0π£Our project, βMechanometabolic Control of Vertebrate Limb Elongation,β has been funded by Wellcome!
Over the next 8 years, weβll collaborate with @manningresearch.bsky.social and Nathalie Agarβs group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!π
Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFΞ² Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...
10.08.2025 14:16 β π 15 π 5 π¬ 0 π 0Nice!
08.08.2025 09:39 β π 0 π 0 π¬ 0 π 0
Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology βοΈπ§¬
π September 1-3, 2025
π Steigenberger Hotel de Saxe, Dresden
Register now (Deadline 31 July 2025): engineering-life-dresden.de
After 15 years of controversy, @science.org retracts βarsenic lifeβ paper
24.07.2025 18:16 β π 60 π 19 π¬ 1 π 6Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1
22.07.2025 20:31 β π 3 π 3 π¬ 0 π 0Great thread by @amichaut.bsky.social
20.07.2025 12:09 β π 1 π 0 π¬ 0 π 0Check out this thread I wrote for @epimechfc.bsky.social β¬οΈ
20.07.2025 09:11 β π 23 π 6 π¬ 0 π 1Congratulations @clementrodier.bsky.social @frankschnorrer.bsky.social et al!
10.07.2025 16:11 β π 2 π 0 π¬ 1 π 0
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
10.07.2025 10:16 β π 99 π 42 π¬ 5 π 5
Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
So cool, Brent!
07.07.2025 08:02 β π 1 π 0 π¬ 1 π 0
SAVE THE DATE!! #2026SDB
π§ͺπ§¬π¬π§«π
(Never been to Vegas π Exciting!!)
Group photo from the Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism Workshop Held at Buxted Park, East Sussex, UK 22-25 June 2025
The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism
Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-DumΓ©nil, Victoria Sanz-Moreno and Giorgio Scita.
#Workshop #Biology #CellBiology #Community #Collaboration #Research
